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Javier Martín-Broto
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Journal Articles

Predictive Value of MRP-1 in Localized High-Risk Soft Tissue Sarcomas: A Translational Research Associated to ISG-STS 1001 Randomized Phase III Trial

Javier Martin-Broto, Maria Lopez-Alvarez, David S. Moura, Rafael Ramos, Paola Collini, Cleofe Romagosa, Silvia Bagué, Salvatore L. Renne, Marta Barisella, Valerie Velasco, Jean-Michel Coindre, Daniel Lopez-Lopez, Joaquin Dopazo, Marco Gambarotti, Luca Braglia, Domenico Franco Merlo, Emanuela Palmerini, Silvia Stacchiotti, Vittorio L. Quagliuolo, Antonio Lopez-Pousa, Giovanni Grignani, Jean-Yves Blay, Antonella Brunello, Antonio Gutierrez, Claudia Valverde, Nadia Hindi, Angelo Paolo Dei Tos, Piero Picci, Paolo G. Casali, Alessandro Gronchi
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12): 2539–2552.
https://doi.org/10.1158/1535-7163.MCT-21-0315
Published: 03 December 2021
View article titled, Predictive Value of MRP-1 in Localized High-Risk Soft Tissue Sarcomas: A Translational Research Associated to ISG-STS 1001 Randomized Phase III Trial
Open the PDF for Predictive Value of MRP-1 in Localized High-Risk Soft Tissue Sarcomas: A Translational Research Associated to ISG-STS 1001 Randomized Phase III Trial in another window
Includes: Supplementary data
Journal Articles

Olaratumab-induced Biomarker Modulation in Sarcomas—Response

Javier Martín-Broto, Patrick M. Peterson, Gerard J. Oakley, Matteo Ceccarelli, Robin L. Jones
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (10): 2094.
https://doi.org/10.1158/1535-7163.MCT-21-0497
Published: 01 October 2021
View article titled, Olaratumab-induced Biomarker Modulation in Sarcomas—Response
Open the PDF for Olaratumab-induced Biomarker Modulation in Sarcomas—Response in another window
Journal Articles

Circulating Tumor Cells and Biomarker Modulation with Olaratumab Monotherapy Followed by Olaratumab plus Doxorubicin: Phase Ib Study in Patients with Soft-Tissue Sarcoma

Javier Martín-Broto, Antonio López Pousa, Andrew S. Brohl, Brian A. Van Tine, Benjamin Powers, Silvia Stacchiotti, Jean-Yves Blay, James S. Hu, Gerard J. Oakley, III, Hong Wang, Anna M. Szpurka, Donna E. Levy, Gary Mo, Matteo Ceccarelli, Robin L. Jones
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2021) 20 (1): 132–141.
https://doi.org/10.1158/1535-7163.MCT-20-0441
Published: 05 January 2021
View article titled, Circulating Tumor Cells and Biomarker Modulation with Olaratumab Monotherapy Followed by Olaratumab plus Doxorubicin: Phase Ib Study in Patients with Soft-Tissue Sarcoma
Open the PDF for Circulating Tumor Cells and Biomarker Modulation with Olaratumab Monotherapy Followed by Olaratumab plus Doxorubicin: Phase Ib Study in Patients with Soft-Tissue Sarcoma in another window
Includes: Supplementary data
Journal Articles

Disruption of TCF/β-Catenin Binding Impairs Wnt Signaling and Induces Apoptosis in Soft Tissue Sarcoma Cells

Esther Martinez-Font, Irene Felipe-Abrio, Silvia Calabuig-Fariñas, Rafael Ramos, Josefa Terrasa, Oliver Vögler, Regina Alemany, Javier Martín-Broto, Antònia Obrador-Hevia
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (6): 1166–1176.
https://doi.org/10.1158/1535-7163.MCT-16-0585
Published: 01 June 2017
View article titled, Disruption of TCF/β-Catenin Binding Impairs Wnt Signaling and Induces Apoptosis in Soft Tissue Sarcoma Cells
Open the PDF for Disruption of TCF/β-Catenin Binding Impairs Wnt Signaling and Induces Apoptosis in Soft Tissue Sarcoma Cells in another window
Includes: Supplementary data
Journal Articles

MRP1 Overexpression Determines Poor Prognosis in Prospectively Treated Patients with Localized High-Risk Soft Tissue Sarcoma of Limbs and Trunk Wall: An ISG/GEIS Study

Javier Martin-Broto, Antonio M. Gutierrez, Rafael F. Ramos, José A. Lopez-Guerrero, Stefano Ferrari, Silvia Stacchiotti, Piero Picci, Silvia Calabuig, Paola Collini, Marco Gambarotti, Silvia Bague, Angelo P. Dei Tos, Elena Palassini, Pablo Luna, Josefina Cruz, Ricardo Cubedo, Javier Martinez-Trufero, Andres Poveda, Paolo G. Casali, Antonio Fernandez-Serra, Antonio Lopez-Pousa, Alessandro Gronchi
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2014) 13 (1): 249–259.
https://doi.org/10.1158/1535-7163.MCT-13-0406
Published: 13 January 2014
View article titled, MRP1 Overexpression Determines Poor Prognosis in Prospectively Treated Patients with Localized High-Risk Soft Tissue Sarcoma of Limbs and Trunk Wall: An ISG/GEIS Study
Open the PDF for MRP1 Overexpression Determines Poor Prognosis in Prospectively Treated Patients with Localized High-Risk Soft Tissue Sarcoma of Limbs and Trunk Wall: An ISG/GEIS Study in another window