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Journal Articles

PCA062, a P-cadherin Targeting Antibody–Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin–expressing Malignancies

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Qing Sheng, Joseph A. D'Alessio, Daniel L. Menezes, Christopher Karim, Yan Tang, Angela Tam, Suzanna Clark, Chi Ying, Anu Connor, Keith G. Mansfield, Jean-Michel Rondeau, Majid Ghoddusi, Felipe C. Geyer, Jane Gu, Margaret E. McLaughlin, Rick Newcombe, GiNell Elliot, William R. Tschantz, Sylvie Lehmann, Christie P. Fanton, Kathy Miller, Thomas Huber, Katherine G. Rendahl, Ursula Jeffry, Nancy K. Pryer, Emma Lees, Paul Kwon, Judith A. Abraham, Jason S. Damiano, Tinya J. Abrams
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (7): 1270–1282.
https://doi.org/10.1158/1535-7163.MCT-20-0708
Published: 01 July 2021
View articletitled, PCA062, a P-cadherin Targeting Antibody–Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin–expressing Malignancies
Open the PDF for PCA062, a P-cadherin Targeting Antibody–Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin–expressing Malignancies in another window
Includes: Supplementary data
Journal Articles

Distinct Transcriptional Programming Drive Response to MAPK Inhibition in BRAFV600-Mutant Melanoma Patient-Derived Xenografts

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Tianshu Feng, Javad Golji, Ailing Li, Xiamei Zhang, David A. Ruddy, Daniel P. Rakiec, Felipe C. Geyer, Jane Gu, Hui Gao, Juliet A. Williams, Darrin D. Stuart, Matthew J. Meyer
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12): 2421–2432.
https://doi.org/10.1158/1535-7163.MCT-19-0028
Published: 02 December 2019
View articletitled, Distinct Transcriptional Programming Drive Response to MAPK Inhibition in BRAFV600-Mutant Melanoma Patient-Derived Xenografts
Open the PDF for Distinct Transcriptional Programming Drive Response to MAPK Inhibition in BRAFV600-Mutant Melanoma Patient-Derived Xenografts in another window
Includes: Supplementary data