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James Barsoum
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Journal Articles

Ganetespib, a Unique Triazolone-Containing Hsp90 Inhibitor, Exhibits Potent Antitumor Activity and a Superior Safety Profile for Cancer Therapy

Weiwen Ying, Zhenjian Du, Lijun Sun, Kevin P. Foley, David A. Proia, Ronald K. Blackman, Dan Zhou, Takayo Inoue, Noriaki Tatsuta, Jim Sang, Shuxia Ye, Jamie Acquaviva, Luisa Shin Ogawa, Yumiko Wada, James Barsoum, Keizo Koya
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (2): 475–484.
https://doi.org/10.1158/1535-7163.MCT-11-0755
Published: 08 February 2012
View article titled, Ganetespib, a Unique Triazolone-Containing Hsp90 Inhibitor, Exhibits Potent Antitumor Activity and a Superior Safety Profile for Cancer Therapy
Open the PDF for Ganetespib, a Unique Triazolone-Containing Hsp90 Inhibitor, Exhibits Potent Antitumor Activity and a Superior Safety Profile for Cancer Therapy in another window
Includes: Supplementary data
Journal Articles

Abstract B199: In vitro and in vivo efficacy of the novel Hsp90 inhibitor STA‐9090 and its synergy with paclitaxel

Weiwen Ying, Ronald K. Blackman, Dinesh Chimmanamada, Zhenjian Du, Kevin P. Foley, Suqin He, Takayo Inoue, David James, Jane Kepros, Tim Korbut, Luisa Shin Ogawa, Cong Peng, Teresa Przewloka, David Proia, Jim Sang, Donald Smith, Noriaki Tatsuta, Chin‐Yu Yang, Chaohua Zhang, Haili Zhang, Shijie Zhang, Shaoguang Li, James Barsoum
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): B199.
https://doi.org/10.1158/1535-7163.TARG-09-B199
Published: 10 December 2009
View article titled, Abstract B199: <em>In vitro</em> and <em>in vivo</em> efficacy of the novel Hsp90 inhibitor STA‐9090 and its synergy with paclitaxel
Journal Articles

Abstract C91: Pharmacodynamic analysis of the Hsp90 inhibitor STA‐9090 in a lung cancer xenograft model supports an infrequent dosing schedule in the clinic

Kevin P. Foley, Takeshi Shimamura, Ron K. Blackman, Christa L. Borgman, Takayo Inoue, Tim Korbut, David Proia, Jim Sang, Luisa Shin Ogawa, Don Smith, Noriaki Tatsuta, Chaohua Zhang, Haili Zhang, Weiwen Ying, Geoffrey I. Shapiro, James Barsoum
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): C91.
https://doi.org/10.1158/1535-7163.TARG-09-C91
Published: 10 December 2009
View article titled, Abstract C91: Pharmacodynamic analysis of the Hsp90 inhibitor STA‐9090 in a lung cancer xenograft model supports an infrequent dosing schedule in the clinic
Journal Articles

Abstract C11: The oxidative stress inducer elesclomol requires copper chelation for its anticancer activity

Masazumi Nagai, Nha Vho, Elena Kostik, Suqin He, Jane Kepros, Luisa S. Ogawa, Takayo Inoue, Ronald K. Blackman, Yumiko Wada, James Barsoum
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): C11.
https://doi.org/10.1158/1535-7163.TARG-09-C11
Published: 10 December 2009
View article titled, Abstract C11: The oxidative stress inducer elesclomol requires copper chelation for its anticancer activity
Journal Articles

Elesclomol induces cancer cell apoptosis through oxidative stress

Jessica R. Kirshner, Suqin He, Vishwasenani Balasubramanyam, Jane Kepros, Chin-Yu Yang, Mei Zhang, Zhenjian Du, James Barsoum, John Bertin
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (8): 2319–2327.
https://doi.org/10.1158/1535-7163.MCT-08-0298
Published: 21 August 2008
View article titled, Elesclomol induces cancer cell apoptosis through oxidative stress
Open the PDF for Elesclomol induces cancer cell apoptosis through oxidative stress in another window
Includes: Supplementary data
Journal Articles

STA-4783 induces apoptosis and enhances the anticancer activity of paclitaxel through induction of oxidative stress

Jessica Kirshner, Zhenjian Du, Jane Kepros, Vish Balasubramanyam, Suqin He, Mei Zhang, Chin-Yu Yang, Kevin Foley, James Barsoum, John Bertin
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): B274.
Published: 01 November 2007
View article titled, STA-4783 induces apoptosis and enhances the anticancer activity of paclitaxel through induction of oxidative stress
Journal Articles

The oxidative stress inducer STA-4783 enhances the in vivo efficacy of multiple anti-cancer therapies in mouse tumor models

Kevin Foley, John Bertin, Kwan Chan, Amy Hutchings, Takayo Inoue, Jessica Kirshner, Timothy Korbut, Long Li, Robert Mihalek, Patricia Rao, Jim Sang, Don Smith, Noriaki Tatsuta, Chaohua Zhang, Dan Zhou, James Barsoum
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): A290.
Published: 01 November 2007
View article titled, The oxidative stress inducer STA-4783 enhances the <em>in vivo</em> efficacy of multiple anti-cancer therapies in mouse tumor models