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James B. DuHadaway
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Journal Articles

The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria

Christopher W. Schultz, Grace A. McCarthy, Teena Nerwal, Avinoam Nevler, James B. DuHadaway, Matthew D. McCoy, Wei Jiang, Samantha Z. Brown, Austin Goetz, Aditi Jain, Valerie S. Calvert, Vikalp Vishwakarma, Dezhen Wang, Ranjan Preet, Joel Cassel, Ross Summer, Hoora Shaghaghi, Yves Pommier, Simone A. Baechler, Michael J. Pishvaian, Talia Golan, Charles J. Yeo, Emanuel F. Petricoin, George C. Prendergast, Joseph Salvino, Pankaj K. Singh, Dan A. Dixon, Jonathan R. Brody
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (11): 2166–2176.
https://doi.org/10.1158/1535-7163.MCT-20-0652
Published: 01 November 2021
View article titled, The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria
Open the PDF for The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria in another window
Includes: Supplementary data
Journal Articles

Zinc Protoporphyrin IX Stimulates Tumor Immunity by Disrupting the Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase

Richard Metz, James B. DuHadaway, Sonja Rust, David H. Munn, Alexander J. Muller, Mario Mautino, George C. Prendergast
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (6): 1864–1871.
https://doi.org/10.1158/1535-7163.MCT-10-0185
Published: 09 June 2010
View article titled, Zinc Protoporphyrin IX Stimulates Tumor Immunity by Disrupting the Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase
Open the PDF for Zinc Protoporphyrin IX Stimulates Tumor Immunity by Disrupting the Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase in another window
Includes: Supplementary data