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Journal Articles

Abstract LB_C12: Alisertib and pembrolizumab in Rb-deficient head and neck squamous cell carcinomas (HNSCC)

Faye M Johnson, Madison P O'Hara, J Jack Lee, Yun Qing, Hai Tran, Soma Ghosh, Lacin Yapindi, Peixin Jiang, Alexandre Reuben, George Blumenschein, Jagannadha Sastry

Mol Cancer Ther (2023) 22 (12_Supplement): LB_C12.

https://doi.org/10.1158/1535-7163.TARG-23-LB_C12

Published: 01 December 2023

View article titled, Abstract LB_C12: Alisertib and pembrolizumab in Rb-deficient head and neck squamous cell carcinomas (HNSCC)

Journal Articles

JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non–Small Cell Lung Cancer

Kazuhiko Shien, Vassiliki A. Papadimitrakopoulou, Dennis Ruder, Carmen Behrens, Li Shen, Neda Kalhor, Juhee Song, J. Jack Lee, Jing Wang, Ximing Tang, Roy S. Herbst, Shinichi Toyooka, Luc Girard, John D. Minna, Jonathan M. Kurie, Ignacio I. Wistuba, Julie G. Izzo

Mol Cancer Ther (2017) 16 (10): 2234–2245.

https://doi.org/10.1158/1535-7163.MCT-17-0148

Published: 02 October 2017

View article titled, JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non–Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

TP53 Alterations Correlate with Response to VEGF/VEGFR Inhibitors: Implications for Targeted Therapeutics

Jennifer J. Wheler, Filip Janku, Aung Naing, Yali Li, Bettzy Stephen, Ralph Zinner, Vivek Subbiah, Siqing Fu, Daniel Karp, Gerald S. Falchook, Apostolia M. Tsimberidou, Sarina Piha-Paul, Roosevelt Anderson, Danxia Ke, Vincent Miller, Roman Yelensky, J. Jack Lee, David Hong, Razelle Kurzrock

Mol Cancer Ther (2016) 15 (10): 2475–2485.

https://doi.org/10.1158/1535-7163.MCT-16-0196

Published: 02 October 2016

View article titled, <em>TP53</em> Alterations Correlate with Response to VEGF/VEGFR Inhibitors: Implications for Targeted Therapeutics

Includes: Supplementary data

Journal Articles

Abstract A76: Prospective evaluation of two-phase NGS platform coupled to active precision oncology decision support in the therapeutic management of patients with advanced cancers

Kenna R. Shaw, Scott Kopetz, Vijaykumar Holla, Beate C. Litzenburger, Walter Kinyua, Blessy Sajan, J. Jack Lee, Russell Broaddus

Mol Cancer Ther (2015) 14 (12_Supplement_2): A76.

https://doi.org/10.1158/1535-7163.TARG-15-A76

Published: 01 December 2015

View article titled, Abstract A76: Prospective evaluation of two-phase NGS platform coupled to active precision oncology decision support in the therapeutic management of patients with advanced cancers

Journal Articles

Triple-Negative Breast Cancer Patients Treated at MD Anderson Cancer Center in Phase I Trials: Improved Outcomes with Combination Chemotherapy and Targeted Agents

Prasanth Ganesan, Stacy Moulder, J. Jack Lee, Filip Janku, Vicente Valero, Ralph G. Zinner, Aung Naing, Siqing Fu, Apostolia M. Tsimberidou, David Hong, Bettzy Stephen, Philip Stephens, Roman Yelensky, Funda Meric-Bernstam, Razelle Kurzrock, Jennifer J. Wheler

Mol Cancer Ther (2014) 13 (12): 3175–3184.

https://doi.org/10.1158/1535-7163.MCT-14-0358

Published: 04 December 2014

View article titled, Triple-Negative Breast Cancer Patients Treated at MD Anderson Cancer Center in Phase I Trials: Improved Outcomes with Combination Chemotherapy and Targeted Agents

Includes: Supplementary data

Journal Articles

Target-Based Therapeutic Matching in Early-Phase Clinical Trials in Patients with Advanced Colorectal Cancer and PIK3CA Mutations

Prasanth Ganesan, Filip Janku, Aung Naing, David S. Hong, Apostolia M. Tsimberidou, Gerald S. Falchook, Jennifer J. Wheler, Sarina A. Piha-Paul, Siqing Fu, Vanda M. Stepanek, J. Jack Lee, Rajyalakshmi Luthra, Michael J. Overman, E. Scott Kopetz, Robert A. Wolff, Razelle Kurzrock

Mol Cancer Ther (2013) 12 (12): 2857–2863.

https://doi.org/10.1158/1535-7163.MCT-13-0319-T

Published: 05 December 2013

View article titled, Target-Based Therapeutic Matching in Early-Phase Clinical Trials in Patients with Advanced Colorectal Cancer and <em>PIK3CA</em> Mutations

Includes: Supplementary data

Journal Articles

Elevated Cyclin D1 Expression Is Predictive for a Benefit from TPF Induction Chemotherapy in Oral Squamous Cell Carcinoma Patients with Advanced Nodal Disease

Lai-Ping Zhong, Dong-Wang Zhu, William N. William, Jr, Ying Liu, Jie Ma, Cheng-Zhe Yang, Xiao Yang, Li-Zhen Wang, Jiang Li, Jeffrey N. Myers, J. Jack Lee, Chen-Ping Zhang, Zhi-Yuan Zhang

Mol Cancer Ther (2013) 12 (6): 1112–1121.

https://doi.org/10.1158/1535-7163.MCT-12-1013

Published: 09 June 2013

View article titled, Elevated Cyclin D1 Expression Is Predictive for a Benefit from TPF Induction Chemotherapy in Oral Squamous Cell Carcinoma Patients with Advanced Nodal Disease

Includes: Supplementary data

Journal Articles

Abstract B161: PIK3CA mutations H1047R are associated with response to PI3K/AKT/mTOR signaling pathway inhibitors in early-phase clinical trials.

Filip Janku, Aung Naing, Vanda T. Stepanek, Gerald S. Falchook, David S. Hong, Apostolia M. Tsimberidou, Siqing Fu, J. Jack Lee, Rajyalakshmi Luthra, Jennifer J. Wheler, Razelle Kurzrock

Mol Cancer Ther (2011) 10 (11_Supplement): B161.

https://doi.org/10.1158/1535-7163.TARG-11-B161

Published: 12 November 2011

View article titled, Abstract B161: PIK3CA mutations H1047R are associated with response to PI3K/AKT/mTOR signaling pathway inhibitors in early-phase clinical trials.

Journal Articles

Serum Signature of Hypoxia-Regulated Factors Is Associated with Progression after Induction Therapy in Head and Neck Squamous Cell Cancer

Mol Cancer Ther (2010) 9 (6): 1755–1763.

https://doi.org/10.1158/1535-7163.MCT-09-1047

Published: 09 June 2010

View article titled, Serum Signature of Hypoxia-Regulated Factors Is Associated with Progression after Induction Therapy in Head and Neck Squamous Cell Cancer

Journal Articles

Angiogenesis in non-small cell lung cancer (NSCLC): Gender differences in tumor and circulating angiogenic factors

Emer Hanrahan, Ludmila Prudkin, Heather Yan Lin, Carmen Behrens, Erminia Massarelli, Matthew Herynk, Danny Du, Marie Wislez, Jonathan Kurie, Roy Herbst, J. Jack Lee, Ignacio Wistuba, John Heymach

Mol Cancer Ther (2007) 6 (11_Supplement): A24.

Published: 01 November 2007

View article titled, Angiogenesis in non-small cell lung cancer (NSCLC): Gender differences in tumor and circulating angiogenic factors

Journal Articles

Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion

Anne S. Tsao, Dandan He, Babita Saigal, Suyu Liu, J. Jack Lee, Srinivasa Bakkannagari, Nelson G. Ordonez, Waun Ki Hong, Ignacio Wistuba, Faye M. Johnson

Mol Cancer Ther (2007) 6 (7): 1962–1972.

https://doi.org/10.1158/1535-7163.MCT-07-0052

Published: 09 July 2007

View article titled, Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion

NARROW

Abstract LB_C12: Alisertib and pembrolizumab in Rb-deficient head and neck squamous cell carcinomas (HNSCC)

JAK1/STAT3 Activation through a Proinflammatory Cytokine Pathway Leads to Resistance to Molecularly Targeted Therapy in Non–Small Cell Lung Cancer

TP53 Alterations Correlate with Response to VEGF/VEGFR Inhibitors: Implications for Targeted Therapeutics

Abstract A76: Prospective evaluation of two-phase NGS platform coupled to active precision oncology decision support in the therapeutic management of patients with advanced cancers

Triple-Negative Breast Cancer Patients Treated at MD Anderson Cancer Center in Phase I Trials: Improved Outcomes with Combination Chemotherapy and Targeted Agents

Target-Based Therapeutic Matching in Early-Phase Clinical Trials in Patients with Advanced Colorectal Cancer and PIK3CA Mutations

Elevated Cyclin D1 Expression Is Predictive for a Benefit from TPF Induction Chemotherapy in Oral Squamous Cell Carcinoma Patients with Advanced Nodal Disease

Abstract B161: PIK3CA mutations H1047R are associated with response to PI3K/AKT/mTOR signaling pathway inhibitors in early-phase clinical trials.

Serum Signature of Hypoxia-Regulated Factors Is Associated with Progression after Induction Therapy in Head and Neck Squamous Cell Cancer

Angiogenesis in non-small cell lung cancer (NSCLC): Gender differences in tumor and circulating angiogenic factors

Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion

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