1-10 of 10
Ignacio Garrido-Laguna
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract P223: Phase 1, first-in-human, dose-escalation, safety, pharmacokinetic, and pharmacodynamic study of oral TP-3654, a PIM kinase inhibitor, in patients with advanced solid tumors

Ignacio Garrido-Laguna, Patrick M. Dillon, Sujan Kabir, Jian Mei, Mark L. Wade, Huyuan Yang, Carl Stapinski, Jason M. Foulks, Steven L. Warner, Clifford Whatcott, Claudia Lebedinsky, Siqing Fu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12_Supplement): P223.
DOI: https://doi.org/10.1158/1535-7163.TARG-21-P223
Published: 01 December 2021
View article
Journal Articles

Genomically Driven Tumors and Actionability across Histologies: BRAF-Mutant Cancers as a Paradigm

Michelle L. Turski, Smruti J. Vidwans, Filip Janku, Ignacio Garrido-Laguna, Javier Munoz, Richard Schwab, Vivek Subbiah, Jordi Rodon, Razelle Kurzrock
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2016) 15 (4): 533–547.
DOI: https://doi.org/10.1158/1535-7163.MCT-15-0643
Published: 05 April 2016
View article
PDF
Journal Articles

A Pilot Clinical Study of Treatment Guided by Personalized Tumorgrafts in Patients with Advanced Cancer

Manuel Hidalgo, Elizabeth Bruckheimer, N.V. Rajeshkumar, Ignacio Garrido-Laguna, Elizabeth De Oliveira, Belen Rubio-Viqueira, Steven Strawn, Michael J. Wick, James Martell, David Sidransky
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (8): 1311–1316.
DOI: https://doi.org/10.1158/1535-7163.MCT-11-0233
Published: 08 August 2011
View article
PDF
Includes: Supplementary data
Journal Articles

PIK3CA Mutations in Patients with Advanced Cancers Treated with PI3K/AKT/mTOR Axis Inhibitors

Filip Janku, Apostolia M. Tsimberidou, Ignacio Garrido-Laguna, Xuemei Wang, Rajyalakshmi Luthra, David S. Hong, Aung Naing, Gerald S. Falchook, John W. Moroney, Sarina A. Piha-Paul, Jennifer J. Wheler, Stacy L. Moulder, Siqing Fu, Razelle Kurzrock
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (3): 558–565.
DOI: https://doi.org/10.1158/1535-7163.MCT-10-0994
Published: 08 March 2011
View article
PDF
Includes: Supplementary data
Journal Articles

Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer

Maria C. Villarroel, N.V. Rajeshkumar, Ignacio Garrido-Laguna, Ana De Jesus-Acosta, Siân Jones, Anirban Maitra, Ralph H. Hruban, James R. Eshleman, Alison Klein, Daniel Laheru, Ross Donehower, Manuel Hidalgo
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (1): 3–8.
DOI: https://doi.org/10.1158/1535-7163.MCT-10-0893
Published: 10 January 2011
View article
PDF
Journal Articles

Abstract A243: SCH727965, a novel potent cyclin dependent kinase inhibitor, inhibits pancreatic tumor growth and Ras‐mediated tumorigenic signaling

Anjali Mishra, Georg Feldmann, Ignacio Garrido‐Laguna, Tikva Dadon, Christopher J. Strock, Rajat Bannerji, Manuel Hidalgo, Anirban Maitra, Barry D. Nelkin
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): A243.
DOI: https://doi.org/10.1158/1535-7163.TARG-09-A243
Published: 10 December 2009
View article
Journal Articles

Abstract A251: MK‐1775, a potent Wee1 inhibitor, synergizes with gemcitabine to achieve tumor regressions in pancreatic tumor xenografts

N.V. Rajeshkumar, Elizabeth De Oliveira, Niki A. Ottenhof, Ignacio Garrido‐Laguna, Maria C. Villarroel, James Watters, Tim Demuth, David Brooks, Shinji Mizuarai, Hiroshi Hirai, Anirban Maitra, Manuel Hidalgo
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): A251.
DOI: https://doi.org/10.1158/1535-7163.TARG-09-A251
Published: 10 December 2009
View article
Journal Articles

Abstract B134: PIK3CA mutations in patients with advanced cancers treated in phase I clinical trials

Filip Janku, Ignacio Garrido‐Laguna, David S. Hong, Apostolia M. Tsimberidou, Aung Naing, Gerald S. Falchook, Jennifer J. Wheler, Stacy L. Moulder, Siqing Fu, Sarina Piha‐Paul, Razelle Kurzrock
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): B134.
DOI: https://doi.org/10.1158/1535-7163.TARG-09-B134
Published: 10 December 2009
View article
Journal Articles

Abstract C246: nab®‐paclitaxel targets tumor stroma and results, combined with gemcitabine, in high efficacy against pancreatic cancer models

Anirban Maitra, N.V. Rajeshkumar, Michelle Rudek, Ignacio Garrido‐Laguna, Daniel Laheru, Jose Iglesias, Neil Desai, Daniel D. Von Hoff, Manuel Hidalgo
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): C246.
DOI: https://doi.org/10.1158/1535-7163.TARG-09-C246
Published: 10 December 2009
View article
Journal Articles

Abstract PR-4: From mice to men: Guiding cancer treatment through Personalized Tumorgraft™ models results in prolonged clinical responses in patients with refractory advanced cancers and discovery of novel predictive biomarkers

Manuel Hidalgo, Steven J. Strawn, Michael Wick, N.V. Rajeshkumar, Ignacio Garrido‐Laguna, David Sidransky, Elizabeth M. Bruckheimer
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): PR-4.
DOI: https://doi.org/10.1158/1535-7163.TARG-09-PR-4
Published: 10 December 2009
View article