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Journal Articles

Abstract B126: AG-881, a brain penetrant, potent, pan-mutant IDH (mIDH) inhibitor for use in mIDH solid and hematologic malignancies

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Katharine Yen, Zenon Konteatis, Zhihua Sui, Erin Artin, Lenny Dang, Kimberly Straley, Erica Tobin, Carl Campos, Hua Yang, Raj Nagaraja, Yue Chen, Hyeryun Kim, Camelia Gliser, Brandon Nicolay, Andrew Olaharski, Lee Silverman, Scott Biller, Shinsan M. Su, Ingo Mellinghoff, Janeta Popovici-Muller
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): B126.
https://doi.org/10.1158/1535-7163.TARG-17-B126
Published: 01 January 2018
View articletitled, Abstract B126: AG-881, a brain penetrant, potent, pan-mutant IDH (mIDH) inhibitor for use in mIDH solid and hematologic malignancies
Journal Articles

The BTK Inhibitor Ibrutinib (PCI-32765) Overcomes Paclitaxel Resistance in ABCB1- and ABCC10-Overexpressing Cells and Tumors

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Hui Zhang, Atish Patel, Yi-Jun Wang, Yun-Kai Zhang, Rishil J. Kathawala, Long-Hui Qiu, Bhargav A. Patel, Li-Hua Huang, Suneet Shukla, Dong-Hua Yang, Suresh V. Ambudkar, Li-Wu Fu, Zhe-Sheng Chen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (6): 1021–1030.
https://doi.org/10.1158/1535-7163.MCT-16-0511
Published: 01 June 2017
View articletitled, The BTK Inhibitor Ibrutinib (PCI-32765) Overcomes Paclitaxel Resistance in ABCB1- and ABCC10-Overexpressing Cells and Tumors
Open the PDF for The BTK Inhibitor Ibrutinib (PCI-32765) Overcomes Paclitaxel Resistance in ABCB1- and ABCC10-Overexpressing Cells and Tumors in another window
Includes: Supplementary data
Journal Articles

Dual PI3K/mTOR Inhibitors, GSK2126458 and PKI-587, Suppress Tumor Progression and Increase Radiosensitivity in Nasopharyngeal Carcinoma

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Tongxin Liu, Quanquan Sun, Qi Li, Hua Yang, Yuqin Zhang, Rong Wang, Xiaoshan Lin, Dong Xiao, Yawei Yuan, Longhua Chen, Wei Wang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (2): 429–439.
https://doi.org/10.1158/1535-7163.MCT-14-0548
Published: 09 February 2015
View articletitled, Dual PI3K/mTOR Inhibitors, GSK2126458 and PKI-587, Suppress Tumor Progression and Increase Radiosensitivity in Nasopharyngeal Carcinoma
Open the PDF for Dual PI3K/mTOR Inhibitors, GSK2126458 and PKI-587, Suppress Tumor Progression and Increase Radiosensitivity in Nasopharyngeal Carcinoma in another window
Includes: Supplementary data
Journal Articles

p37 from Mycoplasma hyorhinis promotes cancer cell invasiveness and metastasis through activation of MMP-2 and followed by phosphorylation of EGFR

Free
Manman Gong, Lin Meng, Beihai Jiang, Jianzhi Zhang, Hua Yang, Jian Wu, Chengchao Shou
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (3): 530–537.
https://doi.org/10.1158/1535-7163.MCT-07-2191
Published: 17 March 2008
View articletitled, p37 from Mycoplasma hyorhinis promotes cancer cell invasiveness and metastasis through activation of MMP-2 and followed by phosphorylation of EGFR
Open the PDF for p37 from Mycoplasma hyorhinis promotes cancer cell invasiveness and metastasis through activation of MMP-2 and followed by phosphorylation of EGFR in another window
Journal Articles

Preclinical evaluation of MLN4924, the first small molecule inhibitor of NEDD8-activating enzyme (NAE) for the treatment of cancer

Free
Teresa Soucy, Peter Smith, Michael Milhollen, Allison Berger, Barbara Davis, Hua Yang, Anya Lublinsky, Julie Zhang, Tary Traore, Usha Narayanan, Jie Yu, James Garnsey, James Gavin, Gabriel Weatherhead, Courtney Cullis, Edward Olhava, Stepan Vyskocil, Mark Rolfe, Steven Langston
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): B280.
Published: 01 November 2007
View articletitled, Preclinical evaluation of MLN4924, the first small molecule inhibitor of NEDD8-activating enzyme (NAE) for the treatment of cancer