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Journal Articles

Suppression of Extracellular Vesicle VEGF-C–mediated Lymphangiogenesis and Pancreatic Cancer Early Dissemination By a Selective HDAC1/2 Inhibitor

Chu-An Wang, Chien-Feng Li, Rho-Chi Huang, Yo-Hua Li, Jing-Ping Liou, Shaw-Jenq Tsai

Mol Cancer Ther (2021) 20 (9): 1550–1560.

DOI: https://doi.org/10.1158/1535-7163.MCT-20-0963

Published: 01 September 2021

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Includes: Supplementary data

Journal Articles

C/EBPβ/AEP Signaling Regulates the Oxidative Stress in Malignant Cancers, Stimulating the Metastasis

Kecheng Lei, Seong Su Kang, Eun Hee Ahn, Chun Chen, Jianming Liao, Xia Liu, Hua Li, Laura E. Edgington-Mitchell, Lingjing Jin, Keqiang Ye

Mol Cancer Ther (2021) 20 (9): 1640–1652.

DOI: https://doi.org/10.1158/1535-7163.MCT-21-0019

Published: 01 September 2021

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Includes: Supplementary data

Journal Articles

Preclinical Development of MGC018, a Duocarmycin-based Antibody–drug Conjugate Targeting B7-H3 for Solid Cancer

Mol Cancer Ther (2020) 19 (11): 2235–2244.

DOI: https://doi.org/10.1158/1535-7163.MCT-20-0116

Published: 03 November 2020

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Includes: Multimedia, Supplementary data

Journal Articles

Pathway-Specific Genome Editing of PI3K/mTOR Tumor Suppressor Genes Reveals that PTEN Loss Contributes to Cetuximab Resistance in Head and Neck Cancer

Hiroki Izumi, Zhiyong Wang, Yusuke Goto, Toshinori Ando, Xingyu Wu, Xuefeng Zhang, Hua Li, Daniel E. Johnson, Jennifer R. Grandis, J. Silvio Gutkind

Mol Cancer Ther (2020) 19 (7): 1562–1571.

DOI: https://doi.org/10.1158/1535-7163.MCT-19-1036

Published: 02 July 2020

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Includes: Supplementary data

Journal Articles

Amplification of the Mutation-Carrying BRCA2 Allele Promotes RAD51 Loading and PARP Inhibitor Resistance in the Absence of Reversion Mutations

Pyoung Hwa Park, Tomomi M. Yamamoto, Hua Li, Allen L. Alcivar, Bing Xia, Yifan Wang, Andrea J. Bernhardy, Kristen M. Turner, Andrew V. Kossenkov, Zachary L. Watson, Kian Behbakht, Silvia Casadei, Elizabeth M. Swisher, Paul S. Mischel, Neil Johnson, Benjamin G. Bitler

Mol Cancer Ther (2020) 19 (2): 602–613.

DOI: https://doi.org/10.1158/1535-7163.MCT-17-0256

Published: 06 February 2020

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Includes: Supplementary data

Journal Articles

Development of MGD007, a gpA33 x CD3-Bispecific DART Protein for T-Cell Immunotherapy of Metastatic Colorectal Cancer

Mol Cancer Ther (2018) 17 (8): 1761–1772.

DOI: https://doi.org/10.1158/1535-7163.MCT-17-1086

Published: 31 July 2018

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Includes: Supplementary data

Journal Articles

Abstract A39: PI3K inhibition in preclinical models of HNSCC

Matthew Louis Hedberg, Hua Li, Yan Zeng, Jennifer Rubin Grandis

Mol Cancer Ther (2015) 14 (7_Supplement): A39.

DOI: https://doi.org/10.1158/1538-8514.PI3K14-A39

Published: 06 July 2015

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Journal Articles

Abstract C246: SH-4-54, a novel small-molecule inhibitor of STAT3, demonstrates significant anti-tumor activity against multiple myeloma.

Zhi Hua Li, Sina Haftchenary, Danielle Croucher, Patrick T. Gunning, Suzanne Trudel

Mol Cancer Ther (2013) 12 (11_Supplement): C246.

DOI: https://doi.org/10.1158/1535-7163.TARG-13-C246

Published: 01 November 2013

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Journal Articles

Abstract A260: BP-4-018, a novel inhibitor of STATs demonstrates anti-myeloma activity in preclinical models: Therapeutic implications of targeting aberrant STAT3 signaling in multiple myeloma.

Danielle C. Croucher, Zhi Hua Li, Brent DG Page, Ellen Wei, Patrick T. Gunning, Suzanne Trudel

Mol Cancer Ther (2013) 12 (11_Supplement): A260.

DOI: https://doi.org/10.1158/1535-7163.TARG-13-A260

Published: 01 November 2013

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Journal Articles

Comparing Histone Deacetylase Inhibitor Responses in Genetically Engineered Mouse Lung Cancer Models and a Window of Opportunity Trial in Patients with Lung Cancer

Tian Ma, Fabrizio Galimberti, Cherie P. Erkmen, Vincent Memoli, Fadzai Chinyengetere, Lorenzo Sempere, Jan H. Beumer, Bean N. Anyang, William Nugent, David Johnstone, Gregory J. Tsongalis, Jonathan M. Kurie, Hua Li, James DiRenzo, Yongli Guo, Sarah J. Freemantle, Konstantin H. Dragnev, Ethan Dmitrovsky

Mol Cancer Ther (2013) 12 (8): 1545–1555.

DOI: https://doi.org/10.1158/1535-7163.MCT-12-0933

Published: 08 August 2013

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Includes: Supplementary data

Journal Articles

Abstract A201: The potent STAT3/5 inhibitor, BP-1–102, demonstrates significant antitumor activity against Waldenstrom macroglobulinemia.

Danielle C. Croucher, Victor H. Jimenez-Zepeda, Brent DG Page, Zhi Hua Li, Ellen Wei, James Turkson, Patrick T. Gunning, Suzanne Trudel

Mol Cancer Ther (2011) 10 (11_Supplement): A201.

DOI: https://doi.org/10.1158/1535-7163.TARG-11-A201

Published: 12 November 2011

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Journal Articles

Abstract A125: Silencing Stat3 signaling in human cancers: Identifying potent small molecule inhibitors of Stat3 function.

Brent D. G. Page, Xialoei Zhang, Jennifer Atkinson, Zhi Hua Li, Aaron D. Schimmer, Suzanne Trudel, James Turkson, Patrick T. Gunning

Mol Cancer Ther (2011) 10 (11_Supplement): A125.

DOI: https://doi.org/10.1158/1535-7163.TARG-11-A125

Published: 12 November 2011

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Journal Articles

Radiosensitization of Head and Neck Squamous Cell Carcinoma by a SMAC-Mimetic Compound, SM-164, Requires Activation of Caspases

Jie Yang, Donna McEachern, Wenyan Li, Mary A. Davis, Hua Li, Meredith A. Morgan, Longchuan Bai, Jonathan T. Sebolt, Haiying Sun, Theodore S. Lawrence, Shaomeng Wang, Yi Sun

Mol Cancer Ther (2011) 10 (4): 658–669.

DOI: https://doi.org/10.1158/1535-7163.MCT-10-0643

Published: 06 April 2011

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Includes: Supplementary data

Journal Articles

Abstract C180: A novel bispecific platform for potent redirected killing of B‐cell lymphoma

Paul A. Moore, Ling Huang, Jonah Rainey, Wenjun Zhang, Steve Burke, Yinhua Yang, Sergey Gorlatov, Hua Li, Ralph Alderson, Nadine Tuallion, Ezio Bonvini, Syd Johnson

Mol Cancer Ther (2009) 8 (12_Supplement): C180.

DOI: https://doi.org/10.1158/1535-7163.TARG-09-C180

Published: 10 December 2009

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Journal Articles

A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1α

Shan Hua Li, Dong Hoon Shin, Yang-Sook Chun, Myung Kyu Lee, Myung-Suk Kim, Jong-Wan Park

Mol Cancer Ther (2008) 7 (12): 3729–3738.

DOI: https://doi.org/10.1158/1535-7163.MCT-08-0074

Published: 15 December 2008

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Includes: Supplementary data

Journal Articles

Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas

Wenhua Piao, Yu Wang, Yasushi Adachi, Hiroyuki Yamamoto, Rong Li, Arisa Imsumran, Hua Li, Tadateru Maehata, Masanori Li, Yoshiaki Arimura, Choon-Taek Lee, Yasuhisa Shinomura, David P. Carbone, Kohzoh Imai

Mol Cancer Ther (2008) 7 (6): 1483–1493.

DOI: https://doi.org/10.1158/1535-7163.MCT-07-2395

Published: 19 June 2008

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Journal Articles

p16 Gene therapy: A potentially efficacious modality for nasopharyngeal carcinoma

Andrew Wing Cheong Lee, Jian-Hua Li, Willa Shi, Anna Li, Emily Ng, Ta-Jen Liu, Henry J. Klamut, Fei-Fei Liu

Mol Cancer Ther (2003) 2 (10): 961–969.

Published: 24 October 2003

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NARROW

Suppression of Extracellular Vesicle VEGF-C–mediated Lymphangiogenesis and Pancreatic Cancer Early Dissemination By a Selective HDAC1/2 Inhibitor

C/EBPβ/AEP Signaling Regulates the Oxidative Stress in Malignant Cancers, Stimulating the Metastasis

Preclinical Development of MGC018, a Duocarmycin-based Antibody–drug Conjugate Targeting B7-H3 for Solid Cancer

Pathway-Specific Genome Editing of PI3K/mTOR Tumor Suppressor Genes Reveals that PTEN Loss Contributes to Cetuximab Resistance in Head and Neck Cancer

Amplification of the Mutation-Carrying BRCA2 Allele Promotes RAD51 Loading and PARP Inhibitor Resistance in the Absence of Reversion Mutations

Development of MGD007, a gpA33 x CD3-Bispecific DART Protein for T-Cell Immunotherapy of Metastatic Colorectal Cancer

Abstract A39: PI3K inhibition in preclinical models of HNSCC

Abstract C246: SH-4-54, a novel small-molecule inhibitor of STAT3, demonstrates significant anti-tumor activity against multiple myeloma.

Abstract A260: BP-4-018, a novel inhibitor of STATs demonstrates anti-myeloma activity in preclinical models: Therapeutic implications of targeting aberrant STAT3 signaling in multiple myeloma.

Comparing Histone Deacetylase Inhibitor Responses in Genetically Engineered Mouse Lung Cancer Models and a Window of Opportunity Trial in Patients with Lung Cancer

Abstract A201: The potent STAT3/5 inhibitor, BP-1–102, demonstrates significant antitumor activity against Waldenstrom macroglobulinemia.

Abstract A125: Silencing Stat3 signaling in human cancers: Identifying potent small molecule inhibitors of Stat3 function.

Radiosensitization of Head and Neck Squamous Cell Carcinoma by a SMAC-Mimetic Compound, SM-164, Requires Activation of Caspases

Abstract C180: A novel bispecific platform for potent redirected killing of B‐cell lymphoma

A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1α

Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas

p16 Gene therapy: A potentially efficacious modality for nasopharyngeal carcinoma

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