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Journal Articles

Pathogenesis and Systemic Treatment of Hepatocellular Carcinoma: Current Status and Prospects

Wanting Lei, Kexun Zhou, Ye Lei, Qiu Li, Hong Zhu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther OF1–OF17.
https://doi.org/10.1158/1535-7163.MCT-24-0403
Published: 05 November 2024
View article titled, Pathogenesis and Systemic Treatment of Hepatocellular Carcinoma: Current Status and Prospects
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Journal Articles

Inhibition of AKT Sensitizes Cancer Cells to Antineoplastic Drugs by Downregulating Flap Endonuclease 1

Hong Zhu, Congye Wu, Ting Wu, Wen Xia, Shusheng Ci, Weiru He, Yilan Zhang, Lulu Li, Shiying Zhou, Jing Zhang, Ashlin M. Edick, Anna Zhang, Fei-Yan Pan, Zhigang Hu, Lingfeng He, Zhigang Guo
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12): 2407–2420.
https://doi.org/10.1158/1535-7163.MCT-18-1215
Published: 02 December 2019
View article titled, Inhibition of AKT Sensitizes Cancer Cells to Antineoplastic Drugs by Downregulating Flap Endonuclease 1
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Includes: Supplementary data
Journal Articles

CT-707, a Novel FAK Inhibitor, Synergizes with Cabozantinib to Suppress Hepatocellular Carcinoma by Blocking Cabozantinib-Induced FAK Activation

Dan-Dan Wang, Ying Chen, Zi-Bo Chen, Fang-Jie Yan, Xiao-Yang Dai, Mei-Dan Ying, Ji Cao, Jian Ma, Pei-Hua Luo, Yong-Xin Han, Yong Peng, Ying-Hui Sun, Hui Zhang, Qiao-Jun He, Bo Yang, Hong Zhu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (12): 2916–2925.
https://doi.org/10.1158/1535-7163.MCT-16-0282
Published: 01 December 2016
View article titled, CT-707, a Novel FAK Inhibitor, Synergizes with Cabozantinib to Suppress Hepatocellular Carcinoma by Blocking Cabozantinib-Induced FAK Activation
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Includes: Supplementary data
Journal Articles

Abstract B155: The E3 ubiquitin protein ligase MDM2 dictates all-trans retinoic acid induced osteoblastic differentiation of osteosarcoma cells by modulating the degradation of RARα

Meidan Ying, Qian Zhou, Xuejing Shao, Ji Cao, Hong Zhu, Bo Yang, Qiaojun He
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): B155.
https://doi.org/10.1158/1535-7163.TARG-15-B155
Published: 01 December 2015
View article titled, Abstract B155: The E3 ubiquitin protein ligase MDM2 dictates all-trans retinoic acid induced osteoblastic differentiation of osteosarcoma cells by modulating the degradation of RARα
Journal Articles

Tirapazamine Sensitizes Hepatocellular Carcinoma Cells to Topoisomerase I Inhibitors via Cooperative Modulation of Hypoxia-Inducible Factor-1α

Tian-Yu Cai, Xiao-Wen Liu, Hong Zhu, Ji Cao, Jun Zhang, Ling Ding, Jian-Shu Lou, Qiao-Jun He, Bo Yang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2014) 13 (3): 630–642.
https://doi.org/10.1158/1535-7163.MCT-13-0490
Published: 09 March 2014
View article titled, Tirapazamine Sensitizes Hepatocellular Carcinoma Cells to Topoisomerase I Inhibitors via Cooperative Modulation of Hypoxia-Inducible Factor-1α
Open the PDF for Tirapazamine Sensitizes Hepatocellular Carcinoma Cells to Topoisomerase I Inhibitors via Cooperative Modulation of Hypoxia-Inducible Factor-1α in another window
Includes: Supplementary data
Journal Articles

Synergistic Antitumor Activity of Gemcitabine and ABT-737 In Vitro and In Vivo through Disrupting the Interaction of USP9X and Mcl-1

Chong Zhang, Tian-yu Cai, Hong Zhu, Liu-qing Yang, Hai Jiang, Xiao-wu Dong, Yong-zhou Hu, Neng-ming Lin, Qiao-jun He, Bo Yang
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (7): 1264–1275.
https://doi.org/10.1158/1535-7163.MCT-10-1091
Published: 06 July 2011
View article titled, Synergistic Antitumor Activity of Gemcitabine and ABT-737 <em>In Vitro and In Vivo</em> through Disrupting the Interaction of USP9X and Mcl-1
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Includes: Supplementary data
Journal Articles

The Superparamagnetic Nanoparticles Carrying the E1A Gene Enhance the Radiosensitivity of Human Cervical Carcinoma in Nude Mice

Liang-Fang Shen, Jia Chen, Shan Zeng, Rong-Rong Zhou, Hong Zhu, Mei-Zuo Zhong, Ruo-Jing Yao, Hong Shen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (7): 2123–2130.
https://doi.org/10.1158/1535-7163.MCT-09-1150
Published: 07 July 2010
View article titled, The Superparamagnetic Nanoparticles Carrying the <em>E1A</em> Gene Enhance the Radiosensitivity of Human Cervical Carcinoma in Nude Mice
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Journal Articles

Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins

Min Huang, Ze-Hong Miao, Hong Zhu, Yu-Jun Cai, Wei Lu, Jian Ding
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (6): 1440–1449.
https://doi.org/10.1158/1535-7163.MCT-07-2116
Published: 19 June 2008
View article titled, Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins
Open the PDF for Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins in another window
Includes: Supplementary data
Journal Articles

MFTZ-1, an actinomycetes subspecies–derived antitumor macrolide, functions as a novel topoisomerase II poison

Cheng-Ying Xie, Hong Zhu, Li-Ping Lin, Ze-Hong Miao, Mei-Yu Geng, Yu-Jun Cai, Yi Chen, Hua-Jun Zhao, Hai-Bin Luo, Xiong-Wen Zhang, Li-Ming Fan, Yue-Mao Shen, Jian Ding
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11): 3059–3070.
https://doi.org/10.1158/1535-7163.MCT-07-0014
Published: 19 November 2007
View article titled, MFTZ-1, an actinomycetes subspecies–derived antitumor macrolide, functions as a novel topoisomerase II poison
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Journal Articles

R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II

Hong Zhu, Min Huang, Fan Yang, Yi Chen, Ze-Hong Miao, Xu-Hong Qian, Yu-Fang Xu, Yu-Xin Qin, Hai-Bin Luo, Xu Shen, Mei-Yu Geng, Yu-Jun Cai, Jian Ding
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (2): 484–495.
https://doi.org/10.1158/1535-7163.MCT-06-0584
Published: 16 February 2007
View article titled, R16, a novel amonafide analogue, induces apoptosis and G<sub>2</sub>-M arrest via poisoning topoisomerase II
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