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Journal Articles

Abstract LB_C13: Development of BLX-3030, a potent, selective, orally available CDK9i shows promise in Pancreatic Ductal Adenocarcinoma (PDAC) models

Kyle Medley, Zhaoliang Li, Chenyu Lin, Yesenia Barrera-Millan, Lynne Kelley, Haiyong Han, Hariprasad Vankayalapati, David J Bearss

Mol Cancer Ther (2023) 22 (12_Supplement): LB_C13.

https://doi.org/10.1158/1535-7163.TARG-23-LB_C13

Published: 01 December 2023

View articletitled, Abstract LB_C13: Development of BLX-3030, a potent, selective, orally available CDK9i shows promise in Pancreatic Ductal Adenocarcinoma (PDAC) models

Journal Articles

Abstract LBA024: IL-36γ induces immune infiltration and suppresses tumor growth in a syngeneic mouse model for pancreatic cancer

Kuntal Halder, Daniel D Von Hoff, Haiyong Han

Mol Cancer Ther (2021) 20 (12_Supplement): LBA024.

https://doi.org/10.1158/1535-7163.TARG-21-LBA024

Published: 01 December 2021

View articletitled, Abstract LBA024: IL-36γ induces immune infiltration and suppresses tumor growth in a syngeneic mouse model for pancreatic cancer

Journal Articles

Abstract A142: Drug combination screen to identify novel synergy with Minnelide

Nanyun Tang, Chris Sereduk, Ashok Saluja, Mohana Velagapudi, Haiyong Han, Daniel D Von Hoff, Hongwei Holly Yin

Mol Cancer Ther (2019) 18 (12_Supplement): A142.

https://doi.org/10.1158/1535-7163.TARG-19-A142

Published: 01 December 2019

View articletitled, Abstract A142: Drug combination screen to identify novel synergy with Minnelide

Journal Articles

Abstract A099: Acoustic Cluster Therapy enhances the efficacy of chemotherapeutic regimens in patient-derived xenograft mouse models for pancreatic ductal adenocarcinoma

Serina Ng, Andrew Healey, Svein Kvåle, Spiros Kotopoulis, Daniel D Von Hoff, Per Christian Sontum, Haiyong Han

Mol Cancer Ther (2019) 18 (12_Supplement): A099.

https://doi.org/10.1158/1535-7163.TARG-19-A099

Published: 01 December 2019

View articletitled, Abstract A099: Acoustic Cluster Therapy enhances the efficacy of chemotherapeutic regimens in patient-derived xenograft mouse models for pancreatic ductal adenocarcinoma

Journal Articles

Abstract LB-A28: Super-enhancer signatures of pancreatic ductal adenocarcinoma and associated fibroblasts

Shaimaa Hussein, Pawan Noel, Kenian Chen, Lauren Metang, Daniel Von Hoff, Haiyong Han, Yin Lin

Mol Cancer Ther (2018) 17 (1_Supplement): LB-A28.

https://doi.org/10.1158/1535-7163.TARG-17-LB-A28

Published: 01 January 2018

View articletitled, Abstract LB-A28: Super-enhancer signatures of pancreatic ductal adenocarcinoma and associated fibroblasts

Journal Articles

Abstract LB-B27: Novel antitumor agent GZ17-6.02 exerts discrete effects on transcriptional regulation in pancreatic cancer cells and cancer associated fibroblasts

Emily Rodela, Pawan Noel, Shaimaa Hussein, Yin C. Lin, Daniel D. Von Hoff, Haiyong Han

Mol Cancer Ther (2018) 17 (1_Supplement): LB-B27.

https://doi.org/10.1158/1535-7163.TARG-17-LB-B27

Published: 01 January 2018

View articletitled, Abstract LB-B27: Novel antitumor agent GZ17-6.02 exerts discrete effects on transcriptional regulation in pancreatic cancer cells and cancer associated fibroblasts

Journal Articles

Abstract C138: Targeting macropinocytosis in pancreatic cancer

James Hunt, Serina Ng, Clifford Whatcott, Daniel D. Von Hoff, Haiyong Han

Mol Cancer Ther (2015) 14 (12_Supplement_2): C138.

https://doi.org/10.1158/1535-7163.TARG-15-C138

Published: 01 December 2015

View articletitled, Abstract C138: Targeting macropinocytosis in pancreatic cancer

Journal Articles

Abstract B213: Isolation of muscle fatigue substance(s) with antitumor activities.

Ruben M. Munoz, Haiyong Han, Daniel D. Von Hoff, Stanley Hoffman

Mol Cancer Ther (2011) 10 (11_Supplement): B213.

https://doi.org/10.1158/1535-7163.TARG-11-B213

Published: 12 November 2011

View articletitled, Abstract B213: Isolation of muscle fatigue substance(s) with antitumor activities.

Journal Articles

Abstract B152: Modulating the activity of nerve growth factor (NGF) and its receptors tropomyosin-related kinase A (TRKA) and p75 neurotrophin receptor (p75NTR) in perineural invasion (PNI) in pancreatic cancer.

Aditi A. Bapat, Ruben M. Munoz, Saaiqa Maredia, Daniel D. Von Hoff, Haiyong Han

Mol Cancer Ther (2011) 10 (11_Supplement): B152.

https://doi.org/10.1158/1535-7163.TARG-11-B152

Published: 12 November 2011

View articletitled, Abstract B152: Modulating the activity of nerve growth factor (NGF) and its receptors tropomyosin-related kinase A (TRKA) and p75 neurotrophin receptor (p75NTR) in perineural invasion (PNI) in pancreatic cancer.

Journal Articles

Abstract A30: Integrated analysis of genomic data and annotations in cancer research

Carolyn V. Ustach, Haiyong Han, Seungchan Kim, Galen Hostetter, Caroline H. Diep, Manuel Hidalgo, Michael Barret, Johnathan J. Keats, Daniel Von Hoff, Christopher Kingsley

Mol Cancer Ther (2009) 8 (12_Supplement): A30.

https://doi.org/10.1158/1535-7163.TARG-09-A30

Published: 10 December 2009

View articletitled, Abstract A30: Integrated analysis of genomic data and annotations in cancer research

Journal Articles

Abstract B170: Downregulation of Yes‐associated protein 1 (YAP1) expression reduces cell proliferation and clonogenicity of pancreatic cancer cells

Caroline H. Diep, Kelly Zucker, Aprill Watanabe, Galen Hostetter, Ruben Munoz, Daniel D. Von Hoff, Haiyong Han

Mol Cancer Ther (2009) 8 (12_Supplement): B170.

https://doi.org/10.1158/1535-7163.TARG-09-B170

Published: 10 December 2009

View articletitled, Abstract B170: Downregulation of Yes‐associated protein 1 (YAP1) expression reduces cell proliferation and clonogenicity of pancreatic cancer cells

Journal Articles

Abstract B225: Use of RNAi to identify targets for further improving the antitumor activity of gemcitabine and nab‐paclitaxel combination therapy in patients with advanced pancreatic cancer

Lifang Xie, Yu Zhao, Daniel Von Hoff, Haiyong Han

Mol Cancer Ther (2009) 8 (12_Supplement): B225.

https://doi.org/10.1158/1535-7163.TARG-09-B225

Published: 10 December 2009

View articletitled, Abstract B225: Use of RNAi to identify targets for further improving the antitumor activity of gemcitabine and nab‐paclitaxel combination therapy in patients with advanced pancreatic cancer

Journal Articles

Enhanced targeting with heterobivalent ligands

Liping Xu, Josef Vagner, Jatinder Josan, Ronald M. Lynch, David L. Morse, Brenda Baggett, Haiyong Han, Eugene A. Mash, Victor J. Hruby, Robert J. Gillies

Mol Cancer Ther (2009) 8 (8): 2356–2365.

https://doi.org/10.1158/1535-7163.MCT-08-1183

Published: 14 August 2009

View articletitled, Enhanced targeting with heterobivalent ligands

Includes: Supplementary data

Journal Articles

UA62784, a novel inhibitor of centromere protein E kinesin-like protein

Meredith C. Henderson, Yeng-Jeng Y. Shaw, Hong Wang, Haiyong Han, Laurence H. Hurley, Gary Flynn, Robert T. Dorr, Daniel D. Von Hoff

Mol Cancer Ther (2009) 8 (1): 36–44.

https://doi.org/10.1158/1535-7163.MCT-08-0789

Published: 12 January 2009

View articletitled, UA62784, a novel inhibitor of centromere protein E kinesin-like protein

Includes: Supplementary data

Journal Articles

Gene expression profiling-based identification of cell-surface targets for developing multimeric ligands in pancreatic cancer

Yoganand Balagurunathan, David L. Morse, Galen Hostetter, Vijayalakshmi Shanmugam, Phillip Stafford, Sonsoles Shack, John Pearson, Maria Trissal, Michael J. Demeure, Daniel D. Von Hoff, Victor J. Hruby, Robert J. Gillies, Haiyong Han

Mol Cancer Ther (2008) 7 (9): 3071–3080.

https://doi.org/10.1158/1535-7163.MCT-08-0402

Published: 11 September 2008

View articletitled, Gene expression profiling-based identification of cell-surface targets for developing multimeric ligands in pancreatic cancer

Includes: Supplementary data

Journal Articles

Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells

Bret Stephens, Haiyong Han, Galen Hostetter, Michael J. Demeure, Daniel D. Von Hoff

Mol Cancer Ther (2008) 7 (1): 202–210.

https://doi.org/10.1158/1535-7163.MCT-07-0542

Published: 17 January 2008

View articletitled, Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells

Journal Articles

Flow-cytometric isolation of neoplastic clones in clinical carcinomas coupled with aCGH enables profiling of novel and previously undetectable genomic aberrations.

Michael Barrett, Alex Robeson, Jeffrey Kiefer, Quick Que, Holly Yin, David Azorsa, Antonio Jimenez, Manuel Hidalgo, Elizabeth Stephan, Kathleen Delgiorno, Michael Demeure, Haiyong Han, Jeffrey Trent, Daniel Von Hoff, Spyro Mousses

Mol Cancer Ther (2007) 6 (11_Supplement): B176.

Published: 01 November 2007

View articletitled, Flow-cytometric isolation of neoplastic clones in clinical carcinomas coupled with aCGH enables profiling of novel and previously undetectable genomic aberrations.

Journal Articles

Evaluation of EP300 expression and mutations in pancreatic cancer

Bret Stephens, Tyler Vovos, Manuel Hidalgo, Daniel Von Hoff, Haiyong Han

Mol Cancer Ther (2007) 6 (11_Supplement): C281.

Published: 01 November 2007

View articletitled, Evaluation of EP300 expression and mutations in pancreatic cancer

Journal Articles

Inhibition of XIAP expression sensitizes pancreatic cancer cells to gemcitabine

Caroline Diep, Daniel Von Hoff, Haiyong Han

Mol Cancer Ther (2007) 6 (11_Supplement): A190.

Published: 01 November 2007

View articletitled, Inhibition of XIAP expression sensitizes pancreatic cancer cells to gemcitabine

Journal Articles

PRL-1 and PRL-2 regulate stress induced Erk and Akt phosphorylation in pancreatic cancer cells

Haiyong Han, Bret Stephens, Daniel Von Hoff

Mol Cancer Ther (2007) 6 (11_Supplement): C258.

Published: 01 November 2007

View articletitled, PRL-1 and PRL-2 regulate stress induced Erk and Akt phosphorylation in pancreatic cancer cells

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Abstract LB_C13: Development of BLX-3030, a potent, selective, orally available CDK9i shows promise in Pancreatic Ductal Adenocarcinoma (PDAC) models

Abstract LBA024: IL-36γ induces immune infiltration and suppresses tumor growth in a syngeneic mouse model for pancreatic cancer

Abstract A142: Drug combination screen to identify novel synergy with Minnelide

Abstract A099: Acoustic Cluster Therapy enhances the efficacy of chemotherapeutic regimens in patient-derived xenograft mouse models for pancreatic ductal adenocarcinoma

Abstract LB-A28: Super-enhancer signatures of pancreatic ductal adenocarcinoma and associated fibroblasts

Abstract LB-B27: Novel antitumor agent GZ17-6.02 exerts discrete effects on transcriptional regulation in pancreatic cancer cells and cancer associated fibroblasts

Abstract C138: Targeting macropinocytosis in pancreatic cancer

Abstract B213: Isolation of muscle fatigue substance(s) with antitumor activities.

Abstract B152: Modulating the activity of nerve growth factor (NGF) and its receptors tropomyosin-related kinase A (TRKA) and p75 neurotrophin receptor (p75NTR) in perineural invasion (PNI) in pancreatic cancer.

Abstract A30: Integrated analysis of genomic data and annotations in cancer research

Abstract B170: Downregulation of Yes‐associated protein 1 (YAP1) expression reduces cell proliferation and clonogenicity of pancreatic cancer cells

Abstract B225: Use of RNAi to identify targets for further improving the antitumor activity of gemcitabine and nab‐paclitaxel combination therapy in patients with advanced pancreatic cancer

Enhanced targeting with heterobivalent ligands

UA62784, a novel inhibitor of centromere protein E kinesin-like protein

Gene expression profiling-based identification of cell-surface targets for developing multimeric ligands in pancreatic cancer

Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells

Flow-cytometric isolation of neoplastic clones in clinical carcinomas coupled with aCGH enables profiling of novel and previously undetectable genomic aberrations.

Evaluation of EP300 expression and mutations in pancreatic cancer

Inhibition of XIAP expression sensitizes pancreatic cancer cells to gemcitabine

PRL-1 and PRL-2 regulate stress induced Erk and Akt phosphorylation in pancreatic cancer cells

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