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Gordon W. Gribble
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Journal Articles

The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis

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Karen Liby, Candice C. Black, Darlene B. Royce, Charlotte R. Williams, Renee Risingsong, Mark M. Yore, Xi Liu, Tadashi Honda, Gordon W. Gribble, William W. Lamph, Thomas A. Sporn, Ethan Dmitrovsky, Michael B. Sporn
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (5): 1251–1257.
https://doi.org/10.1158/1535-7163.MCT-08-0023
Published: 15 May 2008
View articletitled, The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis
Open the PDF for The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis in another window
Journal Articles

Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities

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Karen Liby, Tadashi Honda, Charlotte R. Williams, Renee Risingsong, Darlene B. Royce, Nanjoo Suh, Albena T. Dinkova-Kostova, Katherine K. Stephenson, Paul Talalay, Chitra Sundararajan, Gordon W. Gribble, Michael B. Sporn
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (7): 2113–2119.
https://doi.org/10.1158/1535-7163.MCT-07-0180
Published: 09 July 2007
View articletitled, Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities
Open the PDF for Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities in another window
Journal Articles

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes

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Melinda S. Yates, Masafumi Tauchi, Fumiki Katsuoka, Kathleen C. Flanders, Karen T. Liby, Tadashi Honda, Gordon W. Gribble, Delinda A. Johnson, Jeffrey A. Johnson, Neal C. Burton, Tomás R. Guilarte, Masayuki Yamamoto, Michael B. Sporn, Thomas W. Kensler
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (1): 154–162.
https://doi.org/10.1158/1535-7163.MCT-06-0516
Published: 19 January 2007
View articletitled, Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes
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Journal Articles

The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-κB activation through direct inhibition of IκB kinase β

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Mark M. Yore, Karen T. Liby, Tadashi Honda, Gordon W. Gribble, Michael B. Sporn
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (12): 3232–3239.
https://doi.org/10.1158/1535-7163.MCT-06-0444
Published: 15 December 2006
View articletitled, The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-κB activation through direct inhibition of IκB kinase β
Open the PDF for The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-κB activation through direct inhibition of IκB kinase β in another window
Journal Articles

A Novel Indolocarbazole, ICP-1, Abrogates DNA Damage-induced Cell Cycle Arrest and Enhances Cytotoxicity: Similarities and Differences to the Cell Cycle Checkpoint Abrogator UCN-01

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Alan Eastman, Ethan A. Kohn, Mary Kay Brown, Joerg Rathman, Mark Livingstone, David H. Blank, Gordon W. Gribble
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2002) 1 (12): 1067–1078.
Published: 01 October 2002
View articletitled, A Novel Indolocarbazole, ICP-1, Abrogates DNA Damage-induced Cell Cycle Arrest and Enhances Cytotoxicity: Similarities and Differences to the Cell Cycle Checkpoint Abrogator UCN-01
Open the PDF for A Novel Indolocarbazole, ICP-1, Abrogates DNA Damage-induced Cell Cycle Arrest and Enhances Cytotoxicity: Similarities and Differences to the Cell Cycle Checkpoint Abrogator UCN-01 in another window
Journal Articles

Identification of a Novel Synthetic Triterpenoid, Methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, That Potently Induces Caspase-mediated Apoptosis in Human Lung Cancer Cells

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Kevin B. Kim, Reuben Lotan, Ping Yue, Michael B. Sporn, Nanjoo Suh, Gordon W. Gribble, Tadashi Honda, Gen Sheng Wu, Waun Ki Hong, Shi-Yong Sun
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2002) 1 (3): 177–184.
Published: 01 January 2002
View articletitled, Identification of a Novel Synthetic Triterpenoid, Methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, That Potently Induces Caspase-mediated Apoptosis in Human Lung Cancer Cells
Open the PDF for Identification of a Novel Synthetic Triterpenoid, Methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, That Potently Induces Caspase-mediated Apoptosis in Human Lung Cancer Cells in another window