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George C. Prendergast
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Journal Articles

The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria

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Christopher W. Schultz, Grace A. McCarthy, Teena Nerwal, Avinoam Nevler, James B. DuHadaway, Matthew D. McCoy, Wei Jiang, Samantha Z. Brown, Austin Goetz, Aditi Jain, Valerie S. Calvert, Vikalp Vishwakarma, Dezhen Wang, Ranjan Preet, Joel Cassel, Ross Summer, Hoora Shaghaghi, Yves Pommier, Simone A. Baechler, Michael J. Pishvaian, Talia Golan, Charles J. Yeo, Emanuel F. Petricoin, George C. Prendergast, Joseph Salvino, Pankaj K. Singh, Dan A. Dixon, Jonathan R. Brody
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (11): 2166–2176.
https://doi.org/10.1158/1535-7163.MCT-20-0652
Published: 01 November 2021
View articletitled, The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria
Open the PDF for The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria in another window
Includes: Supplementary data
Journal Articles

Expression Signatures of the Lipid-Based Akt Inhibitors Phosphatidylinositol Ether Lipid Analogues in NSCLC Cells

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Chunyu Zhang, Abdel G. Elkahloun, Hongling Liao, Shannon Delaney, Barbara Saber, Betsy Morrow, George C. Prendergast, M. Christine Hollander, Joell J. Gills, Phillip A. Dennis
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (7): 1137–1148.
https://doi.org/10.1158/1535-7163.MCT-10-1028
Published: 06 July 2011
View articletitled, Expression Signatures of the Lipid-Based Akt Inhibitors Phosphatidylinositol Ether Lipid Analogues in NSCLC Cells
Open the PDF for Expression Signatures of the Lipid-Based Akt Inhibitors Phosphatidylinositol Ether Lipid Analogues in NSCLC Cells in another window
Includes: Supplementary data
Journal Articles

Zinc Protoporphyrin IX Stimulates Tumor Immunity by Disrupting the Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase

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Richard Metz, James B. DuHadaway, Sonja Rust, David H. Munn, Alexander J. Muller, Mario Mautino, George C. Prendergast
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (6): 1864–1871.
https://doi.org/10.1158/1535-7163.MCT-10-0185
Published: 09 June 2010
View articletitled, Zinc Protoporphyrin IX Stimulates Tumor Immunity by Disrupting the Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase
Open the PDF for Zinc Protoporphyrin IX Stimulates Tumor Immunity by Disrupting the Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase in another window
Includes: Supplementary data
Journal Articles

Reversion of RhoC GTPase-induced Inflammatory Breast Cancer Phenotype by Treatment with a Farnesyl Transferase Inhibitor

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Kenneth L. van Golen, LiWei Bao, Melinda M. DiVito, ZhiFen Wu, George C. Prendergast, Sofia D. Merajver
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2002) 1 (8): 575–583.
Published: 01 June 2002
View articletitled, Reversion of RhoC GTPase-induced Inflammatory Breast Cancer Phenotype by Treatment with a Farnesyl Transferase Inhibitor
Open the PDF for Reversion of RhoC GTPase-induced Inflammatory Breast Cancer Phenotype by Treatment with a Farnesyl Transferase Inhibitor in another window