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Gabriel N. Hortobagyi
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Journal Articles

Tumor-Infiltrating Lymphocytes and PD-L1 Expression in Pre- and Posttreatment Breast Cancers in the SWOG S0800 Phase II Neoadjuvant Chemotherapy Trial

Free
Vasiliki Pelekanou, William E. Barlow, Zeina A. Nahleh, Brad Wasserman, Ying-Chun Lo, Marie-Kristin von Wahlde, Daniel Hayes, Gabriel N. Hortobagyi, Julie Gralow, Debu Tripathy, Peggy Porter, Borbala Szekely, Christos Hatzis, David L. Rimm, Lajos Pusztai
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (6): 1324–1331.
https://doi.org/10.1158/1535-7163.MCT-17-1005
Published: 31 May 2018
View articletitled, Tumor-Infiltrating Lymphocytes and PD-L1 Expression in Pre- and Posttreatment Breast Cancers in the SWOG S0800 Phase II Neoadjuvant Chemotherapy Trial
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Journal Articles

Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases

Free
Kazuharu Kai, Kimie Kondo, Xiaoping Wang, Xuemei Xie, Mary K. Pitner, Monica E. Reyes, Angie M. Torres-Adorno, Hiroko Masuda, Gabriel N. Hortobagyi, Chandra Bartholomeusz, Hideyuki Saya, Debu Tripathy, Subrata Sen, Naoto T. Ueno
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12): 2687–2699.
https://doi.org/10.1158/1535-7163.MCT-15-0096
Published: 06 December 2015
View articletitled, Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases
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Includes: Supplementary data
Journal Articles

Bisphosphorylated PEA-15 Sensitizes Ovarian Cancer Cells to Paclitaxel by Impairing the Microtubule-Destabilizing Effect of SCLIP

Free
Xuemei Xie, Chandra Bartholomeusz, Ahmed A. Ahmed, Anna Kazansky, Lixia Diao, Keith A. Baggerly, Gabriel N. Hortobagyi, Naoto T. Ueno
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (6): 1099–1111.
https://doi.org/10.1158/1535-7163.MCT-12-0737
Published: 09 June 2013
View articletitled, Bisphosphorylated PEA-15 Sensitizes Ovarian Cancer Cells to Paclitaxel by Impairing the Microtubule-Destabilizing Effect of SCLIP
Open the PDF for Bisphosphorylated PEA-15 Sensitizes Ovarian Cancer Cells to Paclitaxel by Impairing the Microtubule-Destabilizing Effect of SCLIP in another window
Includes: Supplementary data
Journal Articles

Targeting the IKKβ/mTOR/VEGF Signaling Pathway as a Potential Therapeutic Strategy for Obesity-Related Breast Cancer

Free
Chun-Te Chen, Yi Du, Hirohito Yamaguchi, Jung-Mao Hsu, Hsu-Ping Kuo, Gabriel N. Hortobagyi, Mien-Chie Hung
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (10): 2212–2221.
https://doi.org/10.1158/1535-7163.MCT-12-0180
Published: 09 October 2012
View articletitled, Targeting the IKKβ/mTOR/VEGF Signaling Pathway as a Potential Therapeutic Strategy for Obesity-Related Breast Cancer
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Includes: Supplementary data
Journal Articles

Dual Targeting of Tumor Angiogenesis and Chemotherapy by Endostatin–Cytosine Deaminase–Uracil Phosphoribosyltransferase

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Chun-Te Chen, Hirohito Yamaguchi, Hong-Jen Lee, Yi Du, Heng-Huan Lee, Weiya Xia, Wen-Hsuan Yu, Jennifer L. Hsu, Chia-Jui Yen, Hui-Lung Sun, Yan Wang, Edward T.H. Yeh, Gabriel N. Hortobagyi, Mien-Chie Hung
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (8): 1327–1336.
https://doi.org/10.1158/1535-7163.MCT-10-1117
Published: 08 August 2011
View articletitled, Dual Targeting of Tumor Angiogenesis and Chemotherapy by Endostatin–Cytosine Deaminase–Uracil Phosphoribosyltransferase
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Includes: Supplementary data
Journal Articles

PI3K Pathway Mutations and PTEN Levels in Primary and Metastatic Breast Cancer

Free
Ana M. Gonzalez-Angulo, Jaime Ferrer-Lozano, Katherine Stemke-Hale, Aysegul Sahin, Shuying Liu, Juan A. Barrera, Octavio Burgues, Ana M. Lluch, Huiqin Chen, Gabriel N. Hortobagyi, Gordon B. Mills, Funda Meric-Bernstam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (6): 1093–1101.
https://doi.org/10.1158/1535-7163.MCT-10-1089
Published: 08 June 2011
View articletitled, PI3K Pathway Mutations and PTEN Levels in Primary and Metastatic Breast Cancer
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Journal Articles

Silencing Kinase-Interacting Stathmin Gene Enhances Erlotinib Sensitivity by Inhibiting Ser10 p27 Phosphorylation in Epidermal Growth Factor Receptor–Expressing Breast Cancer

Free
Dongwei Zhang, Ana M. Tari, Ugur Akar, Banu K. Arun, Tiffany A. LaFortune, Rene Nieves-Alicea, Gabriel N. Hortobagyi, Naoto T. Ueno
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (11): 3090–3099.
https://doi.org/10.1158/1535-7163.MCT-10-0362
Published: 09 November 2010
View articletitled, Silencing Kinase-Interacting Stathmin Gene Enhances Erlotinib Sensitivity by Inhibiting Ser10 p27 Phosphorylation in Epidermal Growth Factor Receptor–Expressing Breast Cancer
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Includes: Supplementary data
Journal Articles

Development of Candidate Genomic Markers to Select Breast Cancer Patients for Dasatinib Therapy

Free
Stacy Moulder, Kai Yan, Fei Huang, Kenneth R. Hess, Cornelia Liedtke, Feng Lin, Christos Hatzis, Gabriel N. Hortobagyi, W. Fraser Symmans, Lajos Pusztai
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (5): 1120–1127.
https://doi.org/10.1158/1535-7163.MCT-09-1117
Published: 09 May 2010
View articletitled, Development of Candidate Genomic Markers to Select Breast Cancer Patients for Dasatinib Therapy
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Includes: Supplementary data
Journal Articles

Targeting p70S6K Prevented Lung Metastasis in a Breast Cancer Xenograft Model

Free
Ugur Akar, Bulent Ozpolat, Kapil Mehta, Gabriel Lopez-Berestein, Dongwei Zhang, Naoto T. Ueno, Gabriel N. Hortobagyi, Banu Arun
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (5): 1180–1187.
https://doi.org/10.1158/1535-7163.MCT-09-1025
Published: 09 May 2010
View articletitled, Targeting p70S6K Prevented Lung Metastasis in a Breast Cancer Xenograft Model
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Journal Articles

Activity of lapatinib is independent of EGFR expression level in HER2-overexpressing breast cancer cells

Free
Dongwei Zhang, Ashutosh Pal, William G. Bornmann, Fumiyuki Yamasaki, Francisco J. Esteva, Gabriel N. Hortobagyi, Chandra Bartholomeusz, Naoto T. Ueno
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (7): 1846–1850.
https://doi.org/10.1158/1535-7163.MCT-08-0168
Published: 21 July 2008
View articletitled, Activity of lapatinib is independent of EGFR expression level in HER2-overexpressing breast cancer cells
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Journal Articles

Sensitivity of breast cancer cells to erlotinib depends on cyclin-dependent kinase 2 activity

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Fumiyuki Yamasaki, Dongwei Zhang, Chandra Bartholomeusz, Tamotsu Sudo, Gabriel N. Hortobagyi, Kaoru Kurisu, Naoto T. Ueno
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (8): 2168–2177.
https://doi.org/10.1158/1535-7163.MCT-06-0514
Published: 15 August 2007
View articletitled, Sensitivity of breast cancer cells to erlotinib depends on cyclin-dependent kinase 2 activity
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Journal Articles

AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model

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I-Fen Chen, Fu Ou-Yang, Jen-Yu Hung, Jaw-Ching Liu, Hongying Wang, Shao-Chun Wang, Ming-Feng Hou, Gabriel N. Hortobagyi, Mien-Chie Hung
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (1): 1–7.
https://doi.org/10.1158/1535-7163.MCT-05-0310
Published: 23 January 2006
View articletitled, AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model
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