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Frank Speleman
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Journal Articles

Functional Analysis of the p53 Pathway in Neuroblastoma Cells Using the Small-Molecule MDM2 Antagonist Nutlin-3

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Tom Van Maerken, Ali Rihani, Daniel Dreidax, Sarah De Clercq, Nurten Yigit, Jean-Christophe Marine, Frank Westermann, Anne De Paepe, Jo Vandesompele, Frank Speleman
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (6): 983–993.
https://doi.org/10.1158/1535-7163.MCT-10-1090
Published: 08 June 2011
View articletitled, Functional Analysis of the p53 Pathway in Neuroblastoma Cells Using the Small-Molecule MDM2 Antagonist Nutlin-3
Open the PDF for Functional Analysis of the p53 Pathway in Neuroblastoma Cells Using the Small-Molecule MDM2 Antagonist Nutlin-3 in another window
Includes: Supplementary data
Journal Articles

The Quassinoid Derivative NBT-272 Targets Both the AKT and ERK Signaling Pathways in Embryonal Tumors

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Deborah Castelletti, Giulio Fiaschetti, Valeria Di Dato, Urs Ziegler, Candy Kumps, Katleen De Preter, Massimo Zollo, Frank Speleman, Tarek Shalaby, Daniela De Martino, Thorsten Berg, Angelika Eggert, Alexandre Arcaro, Michael A. Grotzer
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (12): 3145–3157.
https://doi.org/10.1158/1535-7163.MCT-10-0539
Published: 14 December 2010
View articletitled, The Quassinoid Derivative NBT-272 Targets Both the AKT and ERK Signaling Pathways in Embryonal Tumors
Open the PDF for The Quassinoid Derivative NBT-272 Targets Both the AKT and ERK Signaling Pathways in Embryonal Tumors in another window
Includes: Supplementary data