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Frank McCormick
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Journal Articles

Abstract A084: Use of the natural nucleotide, GTP, is essential for the identification of potent, active-state KRASG12C inhibitors that bind in the switch II pocket

Bin Wang, Alok Sharma, James Stice, Brian Smith, Marcin Dyba, Devansh Singh, John-Paul Denson, Dana Rabara, Erik Larsen, Yue Yang, Felice C Lightstone, Andrew Stephen, Dwight Nissley, Frank McCormick, Eli Wallace, Anna E Maciag, Pedro J Beltran
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): A084.
https://doi.org/10.1158/1535-7163.TARG-23-A084
Published: 01 December 2023
View article titled, Abstract A084: Use of the natural nucleotide, GTP, is essential for the identification of potent, active-state KRAS<sup>G12C</sup> inhibitors that bind in the switch II pocket
Journal Articles

Abstract B098: GPX4 is a broadly shared gene vulnerability among residual tumors

Matthew J. Hangauer, Vasanthi S. Viswanathan, Matthew J. Ryan, Dhruv Bole, John K. Eaton, Alexandre Matov, Jacqueline Galeas, Harshil D. Dhruv, Michael E. Berens, Stuart L. Schreiber, Frank McCormick, Michael T. McManus
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): B098.
https://doi.org/10.1158/1535-7163.TARG-17-B098
Published: 01 January 2018
View article titled, Abstract B098: GPX4 is a broadly shared gene vulnerability among residual tumors
Journal Articles

Abstract B048: Activation of PKC inhibits oncogenic KRAS-driven malignancies

Man-Tzu Wang, Jacqueline Galeas, Frank McCormick
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (1_Supplement): B048.
https://doi.org/10.1158/1535-7163.TARG-17-B048
Published: 01 January 2018
View article titled, Abstract B048: Activation of PKC inhibits oncogenic KRAS-driven malignancies
Journal Articles

Abstract CN01-01: Opportunities for systemic treatment using siRNA in nanoparticles.

Frank McCormick
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): CN01-01.
https://doi.org/10.1158/1535-7163.TARG-13-CN01-01
Published: 01 November 2013
View article titled, Abstract CN01-01: Opportunities for systemic treatment using siRNA in nanoparticles.
Journal Articles

Abstract B129: RAF inhibition promotes tumorigenesis in a mouse model of HPV-driven squamous cell carcinoma.

Matthew Holderfield, Edward Lorenzana, John Chan, Majid Ghoddusi, Dylan Daniel, Nancy Pryer, Frank McCormick, Darrin Stuart
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): B129.
https://doi.org/10.1158/1535-7163.TARG-11-B129
Published: 12 November 2011
View article titled, Abstract B129: RAF inhibition promotes tumorigenesis in a mouse model of HPV-driven squamous cell carcinoma.
Journal Articles

Abstract PL05-03: Future challenges of targeted therapy

Frank McCormick
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (12_Supplement): PL05-03.
https://doi.org/10.1158/1535-7163.TARG-09-PL05-03
Published: 10 December 2009
View article titled, Abstract PL05-03: Future challenges of targeted therapy
Journal Articles

Dominant p110α activation in endometrial cancer.

Katsutoshi Oda, Jennifer Okada, David Stokoe, Yuji Taketani, Hiroyuki Kuramoto, Zachary Knight, Kevan Shokat, Frank McCormick
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): A251.
Published: 01 November 2007
View article titled, Dominant p110α activation in endometrial cancer.
Journal Articles

Synergistic effects of multi-level targeting of the MAPK and PI3-kinase pathways in breast cancer cells.

Olga Mirzoeva, Rina Gendelman, Zachary Knight, Richard Neve, Heidi Feiler, Ju Han, Wen-Lin Kuo, Norah Bayani, Doris Siwak, Gordon Mills, Paul Spellman, Kevan Shokat, Frank McCormick, Joe Gray, W. Korn
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): B128.
Published: 01 November 2007
View article titled, Synergistic effects of multi-level targeting of the MAPK and PI3-kinase pathways in breast cancer cells.
Journal Articles

Induction of Apoptosis in Mesothelioma Cells by Antisurvivin Oligonucleotides

Chunyao Xia, Zhidong Xu, Xiaocheng Yuan, Kazutsugu Uematsu, Liang You, Kai Li, Li Li, Frank McCormick, David M. Jablons
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2002) 1 (9): 687–694.
Published: 01 July 2002
View article titled, Induction of Apoptosis in Mesothelioma Cells by Antisurvivin Oligonucleotides
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