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Frank Kozielski
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Journal Articles

Is the Fate of Clinical Candidate Arry-520 Already Sealed? Predicting Resistance in Eg5–Inhibitor Complexes

Rose-Laure Indorato, Sandeep K. Talapatra, Fangzhu Lin, Shozeb Haider, Simon P. Mackay, Frank Kozielski, Dimitrios A. Skoufias
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12): 2394–2406.
https://doi.org/10.1158/1535-7163.MCT-19-0154
Published: 02 December 2019
View article titled, Is the Fate of Clinical Candidate Arry-520 Already Sealed? Predicting Resistance in Eg5–Inhibitor Complexes
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Includes: Multimedia, Supplementary data
Journal Articles

Docetaxel-Resistant Prostate Cancer Cells Remain Sensitive to S-Trityl-l-Cysteine–Mediated Eg5 Inhibition

Carolyn Wiltshire, Babloo L. Singh, Jacqueline Stockley, Janis Fleming, Brendan Doyle, Robert Barnetson, Craig N. Robson, Frank Kozielski, Hing Y. Leung
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (6): 1730–1739.
https://doi.org/10.1158/1535-7163.MCT-09-1103
Published: 09 June 2010
View article titled, Docetaxel-Resistant Prostate Cancer Cells Remain Sensitive to <em>S</em>-Trityl-<sc>l</sc>-Cysteine–Mediated Eg5 Inhibition
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Includes: Supplementary data
Journal Articles

In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities

Salvatore DeBonis, Dimitrios A. Skoufias, Luc Lebeau, Roman Lopez, Gautier Robin, Robert L. Margolis, Richard H. Wade, Frank Kozielski
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2004) 3 (9): 1079–1090.
https://doi.org/10.1158/1535-7163.1079.3.9
Published: 14 September 2004
View article titled, <em>In vitro</em> screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities
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