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Fiona Zhong
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Journal Articles

Calicheamicin Antibody–Drug Conjugates with Improved Properties

Available to Purchase
Breanna S. Vollmar, Chris Frantz, Melissa M. Schutten, Fiona Zhong, Geoffrey del Rosario, Mary Ann T. Go, Shang-Fan Yu, Douglas D. Leipold, Amrita V. Kamath, Carl Ng, Keyang Xu, Josefa dela Cruz-Chuh, Katherine R. Kozak, Jinhua Chen, Zijin Xu, John Wai, Pragya Adhikari, Hans K. Erickson, Peter S. Dragovich, Andrew G. Polson, Thomas H. Pillow
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (6): 1112–1120.
https://doi.org/10.1158/1535-7163.MCT-20-0035
Published: 01 June 2021
View articletitled, Calicheamicin Antibody–Drug Conjugates with Improved Properties
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Includes: Supplementary data
Journal Articles

An Anti–CD22-seco-CBI-Dimer Antibody–Drug Conjugate (ADC) for the Treatment of Non-Hodgkin Lymphoma That Provides a Longer Duration of Response than Auristatin-Based ADCs in Preclinical Models

Available to Purchase
Shang-Fan Yu, Donna W. Lee, Bing Zheng, Geoffrey del Rosario, Douglas Leipold, Helen Booler, Fiona Zhong, Montserrat Carrasco-Triguero, Kyu Hong, Peter Yan, Rebecca K. Rowntree, Melissa M. Schutten, Thomas Pillow, Jack D. Sadowsky, Peter S. Dragovich, Andrew G. Polson
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (2): 340–346.
https://doi.org/10.1158/1535-7163.MCT-20-0046
Published: 05 February 2021
View articletitled, An Anti–CD22-seco-CBI-Dimer Antibody–Drug Conjugate (ADC) for the Treatment of Non-Hodgkin Lymphoma That Provides a Longer Duration of Response than Auristatin-Based ADCs in Preclinical Models
Open the PDF for An Anti–CD22-seco-CBI-Dimer Antibody–Drug Conjugate (ADC) for the Treatment of Non-Hodgkin Lymphoma That Provides a Longer Duration of Response than Auristatin-Based ADCs in Preclinical Models in another window
Includes: Supplementary data
Journal Articles

Correction: An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody–Drug Conjugate for the Treatment of Hormone Receptor–Positive Breast Cancer

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Sunil Bhakta, Lisa M. Crocker, Yvonne Chen, Meredith Hazen, Melissa M. Schutten, Dongwei Li, Coenraad Kuijl, Rachana Ohri, Fiona Zhong, Kirsten A. Poon, Mary Ann T. Go, Eric Cheng, Robert Piskol, Ron Firestein, Aimee Fourie-O'Donohue, Katherine R. Kozak, Helga Raab, Jo-Anne Hongo, Deepak Sampath, Mark S. Dennis, Richard H. Scheller, Paul Polakis, Jagath R. Junutula
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (11): 2182.
https://doi.org/10.1158/1535-7163.MCT-19-0749
Published: 01 November 2019
View articletitled, Correction: An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody–Drug Conjugate for the Treatment of Hormone Receptor–Positive Breast Cancer
Open the PDF for Correction: An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody–Drug Conjugate for the Treatment of Hormone Receptor–Positive Breast Cancer in another window
Journal Articles

An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody–Drug Conjugate for the Treatment of Hormone Receptor–Positive Breast Cancer

Free
Sunil Bhakta, Lisa M. Crocker, Yvonne Chen, Meredith Hazen, Melissa M. Schutten, Dongwei Li, Coenraad Kuijl, Rachana Ohri, Fiona Zhong, Kirsten A. Poon, Mary Ann T. Go, Eric Cheng, Robert Piskol, Ron Firestein, Aimee Fourie-O'Donohue, Katherine R. Kozak, Helga Raab, Jo-Anne Hongo, Deepak Sampath, Mark S. Dennis, Richard H. Scheller, Paul Polakis, Jagath R. Junutula
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2018) 17 (3): 638–649.
https://doi.org/10.1158/1535-7163.MCT-17-0813
Published: 28 February 2018
View articletitled, An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody–Drug Conjugate for the Treatment of Hormone Receptor–Positive Breast Cancer
Open the PDF for An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody–Drug Conjugate for the Treatment of Hormone Receptor–Positive Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody–Drug Conjugates with Self-Immolative Disulfide Linkers

Free
Thomas H. Pillow, Melissa Schutten, Shang-Fan Yu, Rachana Ohri, Jack Sadowsky, Kirsten Achilles Poon, Willy Solis, Fiona Zhong, Geoffrey Del Rosario, Mary Ann T. Go, Jeffrey Lau, Sharon Yee, Jintang He, Luna Liu, Carl Ng, Keyang Xu, Douglas D. Leipold, Amrita V. Kamath, Donglu Zhang, Luke Masterson, Stephen J. Gregson, Philip W. Howard, Fan Fang, Jinhua Chen, Janet Gunzner-Toste, Katherine K. Kozak, Susan Spencer, Paul Polakis, Andrew G. Polson, John A. Flygare, Jagath R. Junutula
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (5): 871–878.
https://doi.org/10.1158/1535-7163.MCT-16-0641
Published: 02 May 2017
View articletitled, Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody–Drug Conjugates with Self-Immolative Disulfide Linkers
Open the PDF for Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody–Drug Conjugates with Self-Immolative Disulfide Linkers in another window
Includes: Supplementary data
Journal Articles

Molecular predictors of response to a humanized anti–insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer

Free
Jiping Zha, Carol O'Brien, Heidi Savage, Ling-Yuh Huw, Fiona Zhong, Leanne Berry, Gail D. Lewis Phillips, Elizabeth Luis, Guy Cavet, Xiaolan Hu, Lukas C. Amler, Mark R. Lackner
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (8): 2110–2121.
https://doi.org/10.1158/1535-7163.MCT-09-0381
Published: 14 August 2009
View articletitled, Molecular predictors of response to a humanized anti–insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer
Open the PDF for Molecular predictors of response to a humanized anti–insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer in another window
Includes: Supplementary data