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Federica Piccioni
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Journal Articles

A Genome-scale CRISPR Screen Identifies the ERBB and mTOR Signaling Networks as Key Determinants of Response to PI3K Inhibition in Pancreatic Cancer

Charlotte K. Milton, Annette J. Self, Paul A. Clarke, Udai Banerji, Federica Piccioni, David E. Root, Steven R. Whittaker
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2020) 19 (7): 1423–1435.
https://doi.org/10.1158/1535-7163.MCT-19-1131
Published: 02 July 2020
View article titled, A Genome-scale CRISPR Screen Identifies the ERBB and mTOR Signaling Networks as Key Determinants of Response to PI3K Inhibition in Pancreatic Cancer
Open the PDF for A Genome-scale CRISPR Screen Identifies the ERBB and mTOR Signaling Networks as Key Determinants of Response to PI3K Inhibition in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract C022: Large scale phenotypic screening using PRISM, integrated with functional genomic screening and transcriptional profiling accelerates target identification of cytotoxic small molecules

Kevin Larpenteur, Lucian de Waal, Li Wang, Mustafa Kocak, Jordan Bryan, Samantha Bender, Sulyman Barkho, Matt Kukurugya, Amy Goodale, Brenton Paolella, Min Cho, James McFarland, Michael Rothberg, Cong Zhu, Colin Trepiccio, Aviad Tsherniak, David Root, Bryson Bennett, Federica Piccioni, Josh Bittker, James Rong, Christopher Mader, David Stokoe, Ari Firestone, Todd R Golub, Jennifer Roth
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): C022.
https://doi.org/10.1158/1535-7163.TARG-19-C022
Published: 01 December 2019
View article titled, Abstract C022: Large scale phenotypic screening using PRISM, integrated with functional genomic screening and transcriptional profiling accelerates target identification of cytotoxic small molecules
Journal Articles

Abstract B121: An oncogene-linked prodrug strategy in lung cancer

Aaron Boudreau, Jennifer Roth, James Rong, Niclas Olsson, Chris Mader, Jordan Byran, Jordan Rossen, Li Wang, Kevin Larpenteur, Amy Goodale, Colin Trepicchio, Samantha Bender, Aviad Tsherniak, Aravind Subramanian, Mustafa Kocak, Federica Piccioni, Josh Bittker, Cong Zhu, Frank Li, Nick Eriksson, Daphne Koller, Fiona McAllister, Todd Golub, Jeff Settleman, Ari Firestone, David Stokoe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): B121.
https://doi.org/10.1158/1535-7163.TARG-19-B121
Published: 01 December 2019
View article titled, Abstract B121: An oncogene-linked prodrug strategy in lung cancer
Journal Articles

RAS–MAPK Reactivation Facilitates Acquired Resistance in FGFR1-Amplified Lung Cancer and Underlies a Rationale for Upfront FGFR–MEK Blockade

Bruno Bockorny, Maria Rusan, Wankun Chen, Rachel G. Liao, Yvonne Li, Federica Piccioni, Jun Wang, Li Tan, Aaron R. Thorner, Tianxia Li, Yanxi Zhang, Changhong Miao, Therese Ovesen, Geoffrey I. Shapiro, David J. Kwiatkowski, Nathanael S. Gray, Matthew Meyerson, Peter S. Hammerman, Adam J. Bass
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (7): 1526–1539.
https://doi.org/10.1158/1535-7163.MCT-17-0464
Published: 01 July 2018
View article titled, RAS–MAPK Reactivation Facilitates Acquired Resistance in <em>FGFR1</em>-Amplified Lung Cancer and Underlies a Rationale for Upfront FGFR–MEK Blockade
Open the PDF for RAS–MAPK Reactivation Facilitates Acquired Resistance in <em>FGFR1</em>-Amplified Lung Cancer and Underlies a Rationale for Upfront FGFR–MEK Blockade in another window
Includes: Supplementary data
Journal Articles

Abstract PR10: A cyclic AMP-regulated melanocyte lineage program confers resistance to MAP kinase pathway inhibition

Cory M. Johannessen, Laura A. Johnson, Federica Piccioni, Aisha Townes, Dennie T. Frederick, Keith T. Flaherty, Jennifer A. Wargo, David E. Root, Levi A. Garraway
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (5_Supplement): PR10.
https://doi.org/10.1158/1535-7163.PMS-PR10
Published: 01 May 2014
View article titled, Abstract PR10: A cyclic AMP-regulated melanocyte lineage program confers resistance to MAP kinase pathway inhibition