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Journal Articles

Abstract LB_C12: Alisertib and pembrolizumab in Rb-deficient head and neck squamous cell carcinomas (HNSCC)

Faye M Johnson, Madison P O'Hara, J Jack Lee, Yun Qing, Hai Tran, Soma Ghosh, Lacin Yapindi, Peixin Jiang, Alexandre Reuben, George Blumenschein, Jagannadha Sastry

Mol Cancer Ther (2023) 22 (12_Supplement): LB_C12.

https://doi.org/10.1158/1535-7163.TARG-23-LB_C12

Published: 01 December 2023

View article titled, Abstract LB_C12: Alisertib and pembrolizumab in Rb-deficient head and neck squamous cell carcinomas (HNSCC)

Journal Articles

Abstract B109: Oral dual PI3K/mTOR inhibitor bimiralisib demonstrates tolerability and a signal of activity in head and neck squamous cell cancer with NOTCH1 loss-of-function mutation

Filip Janku, Faye M. Johnson, Mateusz Opyrchal, Afshin Dowlati, Cinta Hierro, Martin Forester, Sarah P. Blagden, Andreas Wicki, Debora Schmitz, Alex A. Adjei

Mol Cancer Ther (2019) 18 (12_Supplement): B109.

https://doi.org/10.1158/1535-7163.TARG-19-B109

Published: 01 December 2019

View article titled, Abstract B109: Oral dual PI3K/mTOR inhibitor bimiralisib demonstrates tolerability and a signal of activity in head and neck squamous cell cancer with NOTCH1 loss-of-function mutation

Journal Articles

Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2

Alexey V. Danilov, Shanhu Hu, Bernardo Orr, Kristina Godek, Lisa Maria Mustachio, David Sekula, Xi Liu, Masanori Kawakami, Faye M. Johnson, Duane A. Compton, Sarah J. Freemantle, Ethan Dmitrovsky

Mol Cancer Ther (2016) 15 (11): 2758–2766.

https://doi.org/10.1158/1535-7163.MCT-16-0127

Published: 01 November 2016

View article titled, Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2

Includes: Multimedia, Supplementary data

Journal Articles

Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases

Mol Cancer Ther (2016) 15 (10): 2334–2343.

https://doi.org/10.1158/1535-7163.MCT-15-0974

Published: 02 October 2016

View article titled, Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases

Includes: Supplementary data

Journal Articles

A Comprehensive Evaluation of Biomarkers Predictive of Response to PI3K Inhibitors and of Resistance Mechanisms in Head and Neck Squamous Cell Carcinoma

Tuhina Mazumdar, Lauren A. Byers, Patrick Kwok Shing Ng, Gordon B. Mills, Shaohua Peng, Lixia Diao, You-Hong Fan, Katherine Stemke-Hale, John V. Heymach, Jeffrey N. Myers, Bonnie S. Glisson, Faye M. Johnson

Mol Cancer Ther (2014) 13 (11): 2738–2750.

https://doi.org/10.1158/1535-7163.MCT-13-1090

Published: 03 November 2014

View article titled, A Comprehensive Evaluation of Biomarkers Predictive of Response to PI3K Inhibitors and of Resistance Mechanisms in Head and Neck Squamous Cell Carcinoma

Includes: Supplementary data

Journal Articles

Abstract C29: Characterization and identification of specific EGFR mutations in circulating tumor cells (CTCs) isolated from non-small cell lung cancer patients using an antibody independent method, ApoStream™: An update report.

Hai T. Tran, Vladislava Melnikova, Anne S. Tsao, Frank V. Fossella, Faye M. Johnson, Vali Papadimitrakoupoulou, Katherine Richardson, Marcia E. Lewis, Ben Legendre, Kenna L. Anderes, Darren W. Davis, John V. Heymach

Mol Cancer Ther (2013) 12 (11_Supplement): C29.

https://doi.org/10.1158/1535-7163.TARG-13-C29

Published: 01 November 2013

View article titled, Abstract C29: Characterization and identification of specific EGFR mutations in circulating tumor cells (CTCs) isolated from non-small cell lung cancer patients using an antibody independent method, ApoStream™: An update report.

Journal Articles

Abstract A182: Identifying biomarkers of sensitivity to polo-like kinase inhibitors (Plki) in non small cell lung cancer (NSCLC).

Renata Ferrarotto, Manasi Suryavanshi, Suk Young Yoo, Jing Wang, Lauren Byers, Bonnie S. Glisson, John Heymach, Faye M. Johnson

Mol Cancer Ther (2013) 12 (11_Supplement): A182.

https://doi.org/10.1158/1535-7163.TARG-13-A182

Published: 01 November 2013

View article titled, Abstract A182: Identifying biomarkers of sensitivity to polo-like kinase inhibitors (Plki) in non small cell lung cancer (NSCLC).

Journal Articles

Global Evaluation of Eph Receptors and Ephrins in Lung Adenocarcinomas Identifies EphA4 as an Inhibitor of Cell Migration and Invasion

Pierre Saintigny, Shaohua Peng, Li Zhang, Banibrata Sen, Ignacio I. Wistuba, Scott M. Lippman, Luc Girard, John D. Minna, John V. Heymach, Faye M. Johnson

Mol Cancer Ther (2012) 11 (9): 2021–2032.

https://doi.org/10.1158/1535-7163.MCT-12-0030

Published: 06 September 2012

View article titled, Global Evaluation of Eph Receptors and Ephrins in Lung Adenocarcinomas Identifies EphA4 as an Inhibitor of Cell Migration and Invasion

Includes: Supplementary data

Journal Articles

A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant K-ras

Yanan Yang, Marie Wislez, Nobukazu Fujimoto, Ludmila Prudkin, Julie G. Izzo, Futoshi Uno, Lin Ji, Amy E. Hanna, Robert R. Langley, Diane Liu, Faye M. Johnson, Ignacio Wistuba, Jonathan M. Kurie

Mol Cancer Ther (2008) 7 (4): 952–960.

https://doi.org/10.1158/1535-7163.MCT-07-2045

Published: 15 April 2008

View article titled, A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant <em>K-ras</em>

Journal Articles

Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion

Anne S. Tsao, Dandan He, Babita Saigal, Suyu Liu, J. Jack Lee, Srinivasa Bakkannagari, Nelson G. Ordonez, Waun Ki Hong, Ignacio Wistuba, Faye M. Johnson

Mol Cancer Ther (2007) 6 (7): 1962–1972.

https://doi.org/10.1158/1535-7163.MCT-07-0052

Published: 09 July 2007

View article titled, Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion

NARROW

Abstract LB_C12: Alisertib and pembrolizumab in Rb-deficient head and neck squamous cell carcinomas (HNSCC)

Abstract B109: Oral dual PI3K/mTOR inhibitor bimiralisib demonstrates tolerability and a signal of activity in head and neck squamous cell cancer with NOTCH1 loss-of-function mutation

Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2

Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases

A Comprehensive Evaluation of Biomarkers Predictive of Response to PI3K Inhibitors and of Resistance Mechanisms in Head and Neck Squamous Cell Carcinoma

Abstract C29: Characterization and identification of specific EGFR mutations in circulating tumor cells (CTCs) isolated from non-small cell lung cancer patients using an antibody independent method, ApoStream™: An update report.

Abstract A182: Identifying biomarkers of sensitivity to polo-like kinase inhibitors (Plki) in non small cell lung cancer (NSCLC).

Global Evaluation of Eph Receptors and Ephrins in Lung Adenocarcinomas Identifies EphA4 as an Inhibitor of Cell Migration and Invasion

A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant K-ras

Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion

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