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Ernest Hamel
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Journal Articles

Abstract C097: Pyrrolo[2′,3′:3,4]cyclohepta[1,2-d][1,2]oxazoles: A new class of antimitotic agents

Virginia Spanò, Daniele Giallombardo, Alessandra Montalbano, Anna Carbone, Eugenio Gaudio, Roberta Bortolozzi, Ruoli Bai, Giampietro Viola, Ernest Hamel, Francesco Bertoni, Paola Barraja
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): C097.
https://doi.org/10.1158/1535-7163.TARG-19-C097
Published: 01 December 2019
View article titled, Abstract C097: Pyrrolo[2′,3′:3,4]cyclohepta[1,2-<em>d</em>][1,2]oxazoles: A new class of antimitotic agents
Journal Articles

Evading Pgp Activity in Drug-Resistant Cancer Cells: A Structural and Functional Study of Antitubulin Furan Metotica Compounds

Tam Luong Nguyen, Maria Rosaria Cera, Andrea Pinto, Leonardo Lo Presti, Ernest Hamel, Paola Conti, Rick Gussio, Peter De Wulf
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (5): 1103–1111.
https://doi.org/10.1158/1535-7163.MCT-11-1018
Published: 08 May 2012
View article titled, Evading Pgp Activity in Drug-Resistant Cancer Cells: A Structural and Functional Study of Antitubulin Furan Metotica Compounds
Open the PDF for Evading Pgp Activity in Drug-Resistant Cancer Cells: A Structural and Functional Study of Antitubulin Furan Metotica Compounds in another window
Includes: Supplementary data
Journal Articles

Peloruside- and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have βI-Tubulin Mutations and Altered Expression of βII- and βIII-Tubulin Isotypes

Arun Kanakkanthara, Anja Wilmes, Aurora O'Brate, Daniel Escuin, Ariane Chan, Ada Gjyrezi, Janet Crawford, Pisana Rawson, Bronwyn Kivell, Peter T. Northcote, Ernest Hamel, Paraskevi Giannakakou, John H. Miller
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (8): 1419–1429.
https://doi.org/10.1158/1535-7163.MCT-10-1057
Published: 08 August 2011
View article titled, Peloruside- and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have βI-Tubulin Mutations and Altered Expression of βII- and βIII-Tubulin Isotypes
Open the PDF for Peloruside- and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have βI-Tubulin Mutations and Altered Expression of βII- and βIII-Tubulin Isotypes in another window
Includes: Supplementary data
Journal Articles

Significant antitumor activity in vivo following treatment with the microtubule agent ENMD-1198

Theresa M. LaVallee, Patricia A. Burke, Glenn M. Swartz, Ernest Hamel, Gregory E. Agoston, Jamshed Shah, Lita Suwandi, Art D. Hanson, William E. Fogler, Carolyn F. Sidor, Anthony M. Treston
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (6): 1472–1482.
https://doi.org/10.1158/1535-7163.MCT-08-0107
Published: 19 June 2008
View article titled, Significant antitumor activity <em>in vivo</em> following treatment with the microtubule agent ENMD-1198
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Journal Articles

The marine compound Lasonolide A is a potent inducer of premature chromosome condensation and inhibitor of cell adhesion

Yong-Wei Zhang, Ernest Hamel, Arun K Ghosh, Yves Pommier
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): C57.
Published: 01 November 2007
View article titled, The marine compound Lasonolide A is a potent inducer of premature chromosome condensation and inhibitor of cell adhesion
Journal Articles

Design, synthesis and evaluation of microtubule inhibitors phenoxy pyridine (PP) and phenyl sulfanyl pyridine (PSP) analogs for cancer therapy

Ravi Anchoori, Madeleine Kortenhorst, Antonio Jimeno, Taradas Sarkar, Gurulingappa Hallur, P.J Diest, Manuel Hidalgo, Ernest Hamel, Saeed Khan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): B277.
Published: 01 November 2007
View article titled, Design, synthesis and evaluation of microtubule inhibitors phenoxy pyridine (PP) and phenyl sulfanyl pyridine (PSP) analogs for cancer therapy
Journal Articles

A bifunctional colchicinoid that binds to the androgen receptor

Nima Sharifi, Ernest Hamel, Markus A. Lill, Prabhakar Risbood, Charles T. Kane, Jr., Md Tafazzal Hossain, Amanda Jones, James T. Dalton, William L. Farrar
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (8): 2328–2336.
https://doi.org/10.1158/1535-7163.MCT-07-0163
Published: 15 August 2007
View article titled, A bifunctional colchicinoid that binds to the androgen receptor
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Journal Articles

Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein tau is predictive of their activity in pancreatic cancer

Antonio Jimeno, Gurulingappa Hallur, Audrey Chan, Xiangfeng Zhang, George Cusatis, Fonda Chan, Preeti Shah, Rongbing Chen, Ernest Hamel, Elizabeth Garrett-Mayer, Saeed Khan, Manuel Hidalgo
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (5): 1509–1516.
https://doi.org/10.1158/1535-7163.MCT-06-0592
Published: 18 May 2007
View article titled, Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein <em>tau</em> is predictive of their activity in pancreatic cancer
Open the PDF for Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein <em>tau</em> is predictive of their activity in pancreatic cancer in another window