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Eric W.-F. Lam
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Journal Articles

Correction: A Novel Small Molecule Aurora Kinase Inhibitor Attenuates Breast Tumor Initiating Cells and Overcomes Drug Resistance

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Fei-Meng Zheng, Zi-Jie Long, Zhi-Jie Hou, Yu Luo, Ling-Zhi Xu, Jiang-Long Xia, Xiao-Ju Lai, Ji-Wei Liu, Xi Wang, Muhammad Kamran, Min Yan, Shu-Juan Shao, Eric W.-F. Lam, Shao-Wu Wang, Gui Lu, Quentin Liu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (5): 856.
https://doi.org/10.1158/1535-7163.MCT-22-0150
Published: 04 May 2022
View articletitled, Correction: A Novel Small Molecule Aurora Kinase Inhibitor Attenuates Breast Tumor Initiating Cells and Overcomes Drug Resistance
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Journal Articles

Abstract B16: Cetuximab activates Foxo3a via the MAPK p38 to induce apoptosis and reduce cell proliferation in colorectal cancer cells

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Laetitia Marzi, Eve Combes, Nadia VIE, Diego Tosi, Adeline Ayrolles-Torro, Christel Larbouret, Vincent Denis, Laetitia K. Linares, Clara Montagut, Mar Iglesias, Pierre Martineau, Eric W-F Lam, Maguy Del Rio, Céline Gongora
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): B16.
https://doi.org/10.1158/1535-7163.TARG-15-B16
Published: 01 December 2015
View articletitled, Abstract B16: Cetuximab activates Foxo3a via the MAPK p38 to induce apoptosis and reduce cell proliferation in colorectal cancer cells
Journal Articles

A Novel Small-Molecule Aurora Kinase Inhibitor Attenuates Breast Tumor–Initiating Cells and Overcomes Drug Resistance

Free
Fei-Meng Zheng, Zi-Jie Long, Zhi-Jie Hou, Yu Luo, Ling-Zhi Xu, Jiang-Long Xia, Xiao-Ju Lai, Ji-Wei Liu, Xi Wang, Muhammad Kamran, Min Yan, Shu-Juan Shao, Eric W.-F. Lam, Shao-Wu Wang, Gui Lu, Quentin Liu
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2014) 13 (8): 1991–2003.
https://doi.org/10.1158/1535-7163.MCT-13-1029
Published: 01 August 2014
View articletitled, A Novel Small-Molecule Aurora Kinase Inhibitor Attenuates Breast Tumor–Initiating Cells and Overcomes Drug Resistance
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Journal Articles

ATM and p53 Regulate FOXM1 Expression via E2F in Breast Cancer Epirubicin Treatment and Resistance

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Julie Millour, Natalia de Olano, Yoshiya Horimoto, Lara J. Monteiro, Julia K. Langer, Rosa Aligue, Nabil Hajji, Eric W.-F. Lam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (6): 1046–1058.
https://doi.org/10.1158/1535-7163.MCT-11-0024
Published: 08 June 2011
View articletitled, ATM and p53 Regulate FOXM1 Expression via E2F in Breast Cancer Epirubicin Treatment and Resistance
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Includes: Supplementary data
Journal Articles

SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2

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Barrie Peck, Chun-Yuan Chen, Ka-Kei Ho, Paolo Di Fruscia, Stephen S. Myatt, R. Charles Coombes, Matthew J. Fuchter, Chwan-Deng Hsiao, Eric W.-F. Lam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (4): 844–855.
https://doi.org/10.1158/1535-7163.MCT-09-0971
Published: 07 April 2010
View articletitled, SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2
Open the PDF for SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2 in another window
Includes: Supplementary data
Journal Articles

Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer

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Ursula B. McGovern, Richard E. Francis, Barrie Peck, Stephanie K. Guest, Jun Wang, Stephen S. Myatt, Janna Krol, Jimmy M-M. Kwok, Andreas Polychronis, R. Charles Coombes, Eric W-F. Lam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (3): 582–591.
https://doi.org/10.1158/1535-7163.MCT-08-0805
Published: 13 March 2009
View articletitled, Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer
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Includes: Supplementary data
Journal Articles

FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells

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Silvia Fernández de Mattos, Priam Villalonga, Jon Clardy, Eric W-F. Lam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (10): 3237–3246.
https://doi.org/10.1158/1535-7163.MCT-08-0398
Published: 13 October 2008
View articletitled, FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells
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Journal Articles

Thiostrepton selectively targets breast cancer cells through inhibition of forkhead box M1 expression

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Jimmy M-M. Kwok, Stephen S. Myatt, Charles M. Marson, R. Charles Coombes, Demetra Constantinidou, Eric W-F. Lam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (7): 2022–2032.
https://doi.org/10.1158/1535-7163.MCT-08-0188
Published: 21 July 2008
View articletitled, Thiostrepton selectively targets breast cancer cells through inhibition of forkhead box M1 expression
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Journal Articles

Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells

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Rosaline C-Y. Hui, Richard E. Francis, Stephanie K. Guest, Joana R. Costa, Ana R. Gomes, Stephen S. Myatt, Jan J. Brosens, Eric W-F. Lam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (3): 670–678.
https://doi.org/10.1158/1535-7163.MCT-07-0397
Published: 17 March 2008
View articletitled, Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells
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Journal Articles

The transcription factor FOXO3a is a crucial cellular target of gefitinib (Iressa) in breast cancer cells

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Janna Krol, Richard E. Francis, André Albergaria, Andrew Sunters, Andreas Polychronis, R. Charles Coombes, Eric W.-F. Lam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (12): 3169–3179.
https://doi.org/10.1158/1535-7163.MCT-07-0507
Published: 18 December 2007
View articletitled, The transcription factor FOXO3a is a crucial cellular target of gefitinib (Iressa) in breast cancer cells
Open the PDF for The transcription factor FOXO3a is a crucial cellular target of gefitinib (Iressa) in breast cancer cells in another window