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Domenico Coppola
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Journal Articles

Targeting the BRD4-HOXB13 Coregulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate Cancer

Niveditha Nerlakanti, Jiqiang Yao, Duy T. Nguyen, Ami K. Patel, Alexey M. Eroshkin, Harshani R. Lawrence, Muhammad Ayaz, Brent M. Kuenzi, Neha Agarwal, Yunyun Chen, Steven Gunawan, Rezaul M. Karim, Norbert Berndt, John Puskas, Anthony M. Magliocco, Domenico Coppola, Jasreman Dhillon, Jingsong Zhang, Subramaniam Shymalagovindarajan, Uwe Rix, Youngchul Kim, Ranjan Perera, Nicholas J. Lawrence, Ernst Schonbrunn, Kiran Mahajan
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (12): 2796–2810.
https://doi.org/10.1158/1535-7163.MCT-18-0602
Published: 03 December 2018
View article titled, Targeting the BRD4-HOXB13 Coregulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Preclinical Modeling of KIF5B–RET Fusion Lung Adenocarcinoma

Qingling Huang, Valentina E. Schneeberger, Noreen Luetteke, Chengliu Jin, Roha Afzal, Mikalai M. Budzevich, Rikesh J. Makanji, Gary V. Martinez, Tao Shen, Lichao Zhao, Kar-Ming Fung, Eric B. Haura, Domenico Coppola, Jie Wu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2016) 15 (10): 2521–2529.
https://doi.org/10.1158/1535-7163.MCT-16-0258
Published: 02 October 2016
View article titled, Preclinical Modeling of KIF5B–RET Fusion Lung Adenocarcinoma
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Includes: Multimedia, Supplementary data
Journal Articles

Selective Nuclear Export Inhibitor KPT-330 Enhances the Antitumor Activity of Gemcitabine in Human Pancreatic Cancer

Sabiha Kazim, Mokenge P. Malafa, Domenico Coppola, Kazim Husain, Sherma Zibadi, Trinayan Kashyap, Marsha Crochiere, Yosef Landesman, Tami Rashal, Daniel M. Sullivan, Amit Mahipal
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (7): 1570–1581.
https://doi.org/10.1158/1535-7163.MCT-15-0104
Published: 06 July 2015
View article titled, Selective Nuclear Export Inhibitor KPT-330 Enhances the Antitumor Activity of Gemcitabine in Human Pancreatic Cancer
Open the PDF for Selective Nuclear Export Inhibitor KPT-330 Enhances the Antitumor Activity of Gemcitabine in Human Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Purified human chorionic gonadotropin induces apoptosis in breast cancer

Dayami Lopez, Madhavi Sekharam, Domenico Coppola, W. Bradford Carter
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (9): 2837–2844.
https://doi.org/10.1158/1535-7163.MCT-08-0339
Published: 11 September 2008
View article titled, Purified human chorionic gonadotropin induces apoptosis in breast cancer
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Journal Articles

Phase I pharmacokinetic and pharmacodynamic study of the inhibitor of activation of AKT (p-Akt), triciribine phosphate monohydrate (TCN-PM), in solid malignancies

Christopher Garrett, Domenico Coppola, Robert Wenham, Christopher Cubitt, Anthony Neuger, Timothy Frost, Daniel Sullivan, Jin Cheng, Said Sebti
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11_Supplement): B71.
Published: 01 November 2007
View article titled, Phase I pharmacokinetic and pharmacodynamic study of the inhibitor of activation of AKT (p-Akt), triciribine phosphate monohydrate (TCN-PM), in solid malignancies
Journal Articles

Combination Therapy with AG-490 and Interleukin 12 Achieves Greater Antitumor Effects than Either Agent Alone

Lyudmila Burdelya, Robyn Catlett-Falcone, Alexander Levitzki, Fengdong Cheng, Linda B. Mora, Eduardo Sotomayor, Domenico Coppola, JiaZhi Sun, Said Sebti, William S. Dalton, Richard Jove, Hua Yu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2002) 1 (11): 893–899.
Published: 01 September 2002
View article titled, Combination Therapy with AG-490 and Interleukin 12 Achieves Greater Antitumor Effects than Either Agent Alone
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