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Debu Tripathy
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Journal Articles

Targeting CDK7 Enhances the Antitumor Efficacy of Enzalutamide in Androgen Receptor–Positive Triple-Negative Breast Cancer by Inhibiting c-MYC–mediated Tumorigenesis

Xuemei Xie, Maroua Manai, Dileep R. Rampa, Jon A. Fuson, Elizabeth S. Nakasone, Troy Pearson, Bharat S. Kuntal, Debu Tripathy, Naoto T. Ueno, Jangsoon Lee
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther OF1–OF14.
https://doi.org/10.1158/1535-7163.MCT-23-0386
Published: 20 December 2024
View article titled, Targeting CDK7 Enhances the Antitumor Efficacy of Enzalutamide in Androgen Receptor–Positive Triple-Negative Breast Cancer by Inhibiting c-MYC–mediated Tumorigenesis
Open the PDF for Targeting CDK7 Enhances the Antitumor Efficacy of Enzalutamide in Androgen Receptor–Positive Triple-Negative Breast Cancer by Inhibiting c-MYC–mediated Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Abstract C146: VIC-1911, a selective Aurora kinase A inhibitor, synergizes with sacituzumab govitecan in triple-negative breast cancer

Jangsoon Lee, YoungJin Gi, Thomas Myers, Linda Paradiso, Debu Tripathy, Naoto T. Ueno
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): C146.
https://doi.org/10.1158/1535-7163.TARG-23-C146
Published: 01 December 2023
View article titled, Abstract C146: VIC-1911, a selective Aurora kinase A inhibitor, synergizes with sacituzumab govitecan in triple-negative breast cancer
Journal Articles

Birinapant Enhances Gemcitabine's Antitumor Efficacy in Triple-Negative Breast Cancer by Inducing Intrinsic Pathway–Dependent Apoptosis

Xuemei Xie, Jangsoon Lee, Huey Liu, Troy Pearson, Alexander Y. Lu, Debu Tripathy, Gayathri R. Devi, Chandra Bartholomeusz, Naoto T. Ueno
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (2): 296–306.
https://doi.org/10.1158/1535-7163.MCT-19-1160
Published: 05 February 2021
View article titled, Birinapant Enhances Gemcitabine's Antitumor Efficacy in Triple-Negative Breast Cancer by Inducing Intrinsic Pathway–Dependent Apoptosis
Open the PDF for Birinapant Enhances Gemcitabine's Antitumor Efficacy in Triple-Negative Breast Cancer by Inducing Intrinsic Pathway–Dependent Apoptosis in another window
Includes: Supplementary data
Journal Articles

Abstract C016: Oxidative phosphorylation is a metabolic vulnerability in chemotherapy resistant triple negative breast cancer

Kurt Evans, Stacy Moulder, Erkan Yuca, Stephen Scott, Natalia Paez Arango, Maryam Shariati, Christopher P Vellano, Turcin Saridogan, Xiaofeng Zheng, Ana Maria Gonzalez-Angulo, Ming Zhao, Xiaoping Su, Coya Tapia, Ken Chen, Argun Akcakanat, Charles M Perou, Bora Lim, Debu Tripathy, Timothy A Yap, Maria E Di Francesco, Giulio Draetta, Philip Jones, Joe Marszalek, Funda Meric-Bernstam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): C016.
https://doi.org/10.1158/1535-7163.TARG-19-C016
Published: 01 December 2019
View article titled, Abstract C016: Oxidative phosphorylation is a metabolic vulnerability in chemotherapy resistant triple negative breast cancer
Journal Articles

Abstract B104: Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations

Maryam Shariati, Christopher A Bristow, Alessandro Carugo, Tim Heffernan, Xiaofeng Zheng, Michael D Peoples, Debu Tripathy, Funda Meric-Bernstam
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): B104.
https://doi.org/10.1158/1535-7163.TARG-19-B104
Published: 01 December 2019
View article titled, Abstract B104: Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with <em>PIK3CA/AKT1</em> mutations
Journal Articles

Cooperative Effect of Oncogenic MET and PIK3CA in an HGF-Dominant Environment in Breast Cancer

Shuying Liu, Shunqiang Li, Bailiang Wang, Wenbin Liu, Mihai Gagea, Huiqin Chen, Joohyuk Sohn, Napa Parinyanitikul, Tina Primeau, Kim-Anh Do, George F. Vande Woude, John Mendelsohn, Naoto T. Ueno, Gordon B. Mills, Debu Tripathy, Ana M. Gonzalez-Angulo
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2019) 18 (2): 399–412.
https://doi.org/10.1158/1535-7163.MCT-18-0710
Published: 04 February 2019
View article titled, Cooperative Effect of Oncogenic <em>MET</em> and <em>PIK3CA</em> in an HGF-Dominant Environment in Breast Cancer
Open the PDF for Cooperative Effect of Oncogenic <em>MET</em> and <em>PIK3CA</em> in an HGF-Dominant Environment in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Tumor-Infiltrating Lymphocytes and PD-L1 Expression in Pre- and Posttreatment Breast Cancers in the SWOG S0800 Phase II Neoadjuvant Chemotherapy Trial

Vasiliki Pelekanou, William E. Barlow, Zeina A. Nahleh, Brad Wasserman, Ying-Chun Lo, Marie-Kristin von Wahlde, Daniel Hayes, Gabriel N. Hortobagyi, Julie Gralow, Debu Tripathy, Peggy Porter, Borbala Szekely, Christos Hatzis, David L. Rimm, Lajos Pusztai
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (6): 1324–1331.
https://doi.org/10.1158/1535-7163.MCT-17-1005
Published: 31 May 2018
View article titled, Tumor-Infiltrating Lymphocytes and PD-L1 Expression in Pre- and Posttreatment Breast Cancers in the SWOG S0800 Phase II Neoadjuvant Chemotherapy Trial
Open the PDF for Tumor-Infiltrating Lymphocytes and PD-L1 Expression in Pre- and Posttreatment Breast Cancers in the SWOG S0800 Phase II Neoadjuvant Chemotherapy Trial in another window
Journal Articles

Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases

Kazuharu Kai, Kimie Kondo, Xiaoping Wang, Xuemei Xie, Mary K. Pitner, Monica E. Reyes, Angie M. Torres-Adorno, Hiroko Masuda, Gabriel N. Hortobagyi, Chandra Bartholomeusz, Hideyuki Saya, Debu Tripathy, Subrata Sen, Naoto T. Ueno
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12): 2687–2699.
https://doi.org/10.1158/1535-7163.MCT-15-0096
Published: 06 December 2015
View article titled, Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases
Open the PDF for Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases in another window
Includes: Supplementary data