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Deborah Wilsker
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Journal Articles

Abstract B037: A pharmacodynamic pilot study of DS8201a in patients with HER2 expressing advanced solid tumors

Sarah J Shin, Geraldine O'Sullivan-Coyne, Elizabeth K Lee, Arjun Mittra, Cora N Sternberg, Mary Jane Ong, Deborah Wilsker, Katherine Ferry-Galow, Jared Foster, Lamin Juwara, Naoko Takebe, Cheryl A Pickett, Ralph Parchment, James Doroshow, Alice Chen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): B037.
https://doi.org/10.1158/1535-7163.TARG-23-B037
Published: 01 December 2023
View article titled, Abstract B037: A pharmacodynamic pilot study of DS8201a in patients with HER2 expressing advanced solid tumors
Journal Articles

Abstract B138: Pharmacodynamics-driven phase 2 trial of talazoparib in patients with advanced solid tumors and aberrations in genes involved in DNA damage response

Brian Ko, Geraldine H O'Sullivan Coyne, Abdul Rafeh Naqash, Thomas J George, David DeRemer, Larry Rubinstein, Jennifer Zlott, Deborah Wilsker, Donna Ketchum, Stephanie Runkle, Katherine V Ferry-Galow, Ralph E Parchment, Naoko Takebe, Sarah Shin, Andrea R Voth, Jiuping Ji, S. Percy Ivy, James H Doroshow, Alice P Chen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): B138.
https://doi.org/10.1158/1535-7163.TARG-23-B138
Published: 01 December 2023
View article titled, Abstract B138: Pharmacodynamics-driven phase 2 trial of talazoparib in patients with advanced solid tumors and aberrations in genes involved in DNA damage response
Journal Articles

Abstract A050: Validation of β-catenin as a tumor segmentation marker for delineating tumor from stromal tissues in quantitative multiplex immunofluorescence analysis of formalin-fixed, paraffin-embedded biopsy specimens

Tony Navas, Robert J. Kinders, Hala Makhlouf, Scott M. Lawrence, Rodrigo Chuaqui, Krisitin Fino, Angie Dull, Katherine Ferry-Galow, Deborah Wilsker, Alice P. Chen, Shivaani Kummar, Ralph E. Parchment, James H. Doroshow
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): A050.
https://doi.org/10.1158/1535-7163.TARG-19-A050
Published: 01 December 2019
View article titled, Abstract A050: Validation of β-catenin as a tumor segmentation marker for delineating tumor from stromal tissues in quantitative multiplex immunofluorescence analysis of formalin-fixed, paraffin-embedded biopsy specimens
Journal Articles

Abstract PR11: Use of a DNA damage multiplex immunofluorescence assay to monitor pharmacodynamic markers following in vitro exposure to therapeutic agents.

Allison M. Marrero, Deborah Wilsker, Scott M. Lawrence, Thomas D. Pfister, John Hirt, Ralph E. Parchment, Joseph E. Tomaszewski, James H. Doroshow, Robert J. Kinders
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): PR11.
https://doi.org/10.1158/1535-7163.TARG-13-PR11
Published: 01 November 2013
View article titled, Abstract PR11: Use of a DNA damage multiplex immunofluorescence assay to monitor pharmacodynamic markers following in vitro exposure to therapeutic agents.
Journal Articles

Targeted Mutations in the ATR Pathway Define Agent-Specific Requirements for Cancer Cell Growth and Survival

Deborah Wilsker, Jon H. Chung, Ivan Pradilla, Eva Petermann, Thomas Helleday, Fred Bunz
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (1): 98–107.
https://doi.org/10.1158/1535-7163.MCT-11-0675
Published: 09 January 2012
View article titled, Targeted Mutations in the ATR Pathway Define Agent-Specific Requirements for Cancer Cell Growth and Survival
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Includes: Supplementary data
Journal Articles

Loss of ataxia telangiectasia mutated– and Rad3-related function potentiates the effects of chemotherapeutic drugs on cancer cell survival

Deborah Wilsker, Fred Bunz
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (4): 1406–1413.
https://doi.org/10.1158/1535-7163.MCT-06-0679
Published: 12 April 2007
View article titled, Loss of ataxia telangiectasia mutated– and Rad3-related function potentiates the effects of chemotherapeutic drugs on cancer cell survival
Open the PDF for Loss of ataxia telangiectasia mutated– and Rad3-related function potentiates the effects of chemotherapeutic drugs on cancer cell survival in another window