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David S. Hsu
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Journal Articles

A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer

Jason A. Somarelli, Roham Salman Roghani, Ali Sanjari Moghaddam, Beatrice C. Thomas, Gabrielle Rupprecht, Kathryn E. Ware, Erdem Altunel, John B. Mantyh, So Young Kim, Shannon J. McCall, Xiling Shen, Christopher R. Mantyh, David S. Hsu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (12): 2516–2527.
https://doi.org/10.1158/1535-7163.MCT-20-0454
Published: 02 December 2020
View article titled, A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer
Open the PDF for A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Preclinical Testing of a Novel Niclosamide Stearate Prodrug Therapeutic (NSPT) Shows Efficacy Against Osteosarcoma

Gireesh B. Reddy, David L. Kerr, Ivan Spasojevic, Artak Tovmasyan, David S. Hsu, Brian E. Brigman, Jason A. Somarelli, David Needham, William C. Eward
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (7): 1448–1461.
https://doi.org/10.1158/1535-7163.MCT-19-0689
Published: 02 July 2020
View article titled, Preclinical Testing of a Novel Niclosamide Stearate Prodrug Therapeutic (NSPT) Shows Efficacy Against Osteosarcoma
Open the PDF for Preclinical Testing of a Novel Niclosamide Stearate Prodrug Therapeutic (NSPT) Shows Efficacy Against Osteosarcoma in another window
Includes: Supplementary data
Journal Articles

Characterization of an Oxaliplatin Sensitivity Predictor in a Preclinical Murine Model of Colorectal Cancer

Mickey K. Kim, Takuya Osada, William T. Barry, Xiao Yi Yang, Jennifer A. Freedman, Katherine A. Tsamis, Michael Datto, Bryan M. Clary, Timothy Clay, Michael A. Morse, Philip G. Febbo, H. Kim Lyerly, David S. Hsu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (7): 1500–1509.
https://doi.org/10.1158/1535-7163.MCT-11-0937
Published: 05 July 2012
View article titled, Characterization of an Oxaliplatin Sensitivity Predictor in a Preclinical Murine Model of Colorectal Cancer
Open the PDF for Characterization of an Oxaliplatin Sensitivity Predictor in a Preclinical Murine Model of Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

A genomic approach to identify molecular pathways associated with chemotherapy resistance

Richard F. Riedel, Alessandro Porrello, Emily Pontzer, Emily J. Chenette, David S. Hsu, Bala Balakumaran, Anil Potti, Joseph Nevins, Phillip G. Febbo
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (10): 3141–3149.
https://doi.org/10.1158/1535-7163.MCT-08-0642
Published: 13 October 2008
View article titled, A genomic approach to identify molecular pathways associated with chemotherapy resistance
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Includes: Supplementary data