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Abstract C023: IKS01, a next generation antibody drug conjugate, shows target-dependent efficacy in a platinum-resistant tumor model with low levels of folate receptor α expression

Jenny Thirlway, Adam Lodge, Andria Pelava, Daniel J Williamson, Davide Carta, Majid Al Nakeeb, Justyna Mysliwy, Paul J.M. Jackson, David E Thurston, Robert J Lutz

Mol Cancer Ther (2019) 18 (12_Supplement): C023.

https://doi.org/10.1158/1535-7163.TARG-19-C023

Published: 01 December 2019

View articletitled, Abstract C023: IKS01, a next generation antibody drug conjugate, shows target-dependent efficacy in a platinum-resistant tumor model with low levels of folate receptor α expression

Journal Articles

Abstract C030: A new low potency DNA guanine monoalkylating ADC payload with enhanced in vivo tolerability

Nicolas Veillard, Paolo Andriollo, Francesco Cascio, Paul J. M. Jackson, David E. Thurston

Mol Cancer Ther (2019) 18 (12_Supplement): C030.

https://doi.org/10.1158/1535-7163.TARG-19-C030

Published: 01 December 2019

View articletitled, Abstract C030: A new low potency DNA guanine monoalkylating ADC payload with enhanced in vivo tolerability

Journal Articles

Abstract A125: Fragment-based approach to develop small-molecule STAT3 transcription factor inhibitors

Kazi S. Nahar, Shirin Jamshidi, David E. Thurston, Khondaker Miraz Rahman

Mol Cancer Ther (2018) 17 (1_Supplement): A125.

https://doi.org/10.1158/1535-7163.TARG-17-A125

Published: 01 January 2018

View articletitled, Abstract A125: Fragment-based approach to develop small-molecule STAT3 transcription factor inhibitors

Journal Articles

Abstract B204: Targeting key DNA/RNA heteroduplex of telomerase by small-molecule ligands.

Mohammad K. Islam, David E. Thurston, Khondaker M. Rahman

Mol Cancer Ther (2013) 12 (11_Supplement): B204.

https://doi.org/10.1158/1535-7163.TARG-13-B204

Published: 01 November 2013

View articletitled, Abstract B204: Targeting key DNA/RNA heteroduplex of telomerase by small-molecule ligands.

Journal Articles

Abstract A228: Noninvasive magnetic resonance spectroscopic PD markers of a minor‐groove interstrand cross‐linking agent (BN2629) in human colon carcinoma and melanoma xenografts

Yuen‐Li Chung, Helen Troy, Marion Stubbs, David E. Thurston, Ian R. Judson, Martin O. Leach, John R. Griffiths

Mol Cancer Ther (2009) 8 (12_Supplement): A228.

https://doi.org/10.1158/1535-7163.TARG-09-A228

Published: 10 December 2009

View articletitled, Abstract A228: Noninvasive magnetic resonance spectroscopic PD markers of a minor‐groove interstrand cross‐linking agent (BN2629) in human colon carcinoma and melanoma xenografts

Journal Articles

Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78

Minal Kotecha, Jerome Kluza, Geoff Wells, C. Caroline O'Hare, Claudia Forni, Roberto Mantovani, Philip W. Howard, Peter Morris, David E. Thurston, John A. Hartley, Daniel Hochhauser

Mol Cancer Ther (2008) 7 (5): 1319–1328.

https://doi.org/10.1158/1535-7163.MCT-07-0475

Published: 15 May 2008

View articletitled, Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78

Journal Articles

Time-dependent cytotoxicity induced by SJG-136 (NSC 694501): influence of the rate of interstrand cross-link formation on DNA damage signaling

Stéphanie Arnould, Victoria J. Spanswick, Janet S. Macpherson, John A. Hartley, David E. Thurston, Duncan I. Jodrell, Sylvie M. Guichard

Mol Cancer Ther (2006) 5 (6): 1602–1609.

https://doi.org/10.1158/1535-7163.MCT-06-0018

Published: 03 July 2006

View articletitled, Time-dependent cytotoxicity induced by SJG-136 (NSC 694501): influence of the rate of interstrand cross-link formation on DNA damage signaling

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Abstract C023: IKS01, a next generation antibody drug conjugate, shows target-dependent efficacy in a platinum-resistant tumor model with low levels of folate receptor α expression

Abstract C030: A new low potency DNA guanine monoalkylating ADC payload with enhanced in vivo tolerability

Abstract A125: Fragment-based approach to develop small-molecule STAT3 transcription factor inhibitors

Abstract B204: Targeting key DNA/RNA heteroduplex of telomerase by small-molecule ligands.

Abstract A228: Noninvasive magnetic resonance spectroscopic PD markers of a minor‐groove interstrand cross‐linking agent (BN2629) in human colon carcinoma and melanoma xenografts

Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78

Time-dependent cytotoxicity induced by SJG-136 (NSC 694501): influence of the rate of interstrand cross-link formation on DNA damage signaling

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Abstract C023: IKS01, a next generation antibody drug conjugate, shows target-dependent efficacy in a platinum-resistant tumor model with low levels of folate receptor α expression

Abstract C030: A new low potency DNA guanine monoalkylating ADC payload with enhanced in vivo tolerability

Abstract A125: Fragment-based approach to develop small-molecule STAT3 transcription factor inhibitors

Abstract B204: Targeting key DNA/RNA heteroduplex of telomerase by small-molecule ligands.

Abstract A228: Noninvasive magnetic resonance spectroscopic PD markers of a minor‐groove interstrand cross‐linking agent (BN2629) in human colon carcinoma and melanoma xenografts

Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78

Time-dependent cytotoxicity induced by SJG-136 (NSC 694501): influence of the rate of interstrand cross-link formation on DNA damage signaling

Email alerts

AACR Journals

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