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Daniel Hochhauser
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Journal Articles

Treatment with Gefitinib or Lapatinib Induces Drug Resistance through Downregulation of Topoisomerase IIα Expression

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Jaishree Bhosle, Konstantinos Kiakos, Andrew C.G. Porter, Jenny Wu, Andreas Makris, John A Hartley, Daniel Hochhauser
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (12): 2897–2908.
https://doi.org/10.1158/1535-7163.MCT-12-1049
Published: 05 December 2013
View articletitled, Treatment with Gefitinib or Lapatinib Induces Drug Resistance through Downregulation of Topoisomerase IIα Expression
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Includes: Supplementary data
Journal Articles

A Phase II Study of Temozolomide in Patients with Advanced Aerodigestive Tract and Colorectal Cancers and Methylation of the O6-Methylguanine-DNA Methyltransferase Promoter

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Daniel Hochhauser, Rob Glynne-Jones, Vanessa Potter, Cristina Grávalos, Thomas J. Doyle, Kumudu Pathiraja, Qing Zhang, Ling Zhang, Edward A. Sausville
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (5): 809–818.
https://doi.org/10.1158/1535-7163.MCT-12-0710
Published: 08 May 2013
View articletitled, A Phase II Study of Temozolomide in Patients with Advanced Aerodigestive Tract and Colorectal Cancers and Methylation of the O6-Methylguanine-DNA Methyltransferase Promoter
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Journal Articles

Involvement of the HER2 pathway in repair of DNA damage produced by chemotherapeutic agents

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Julien J.M. Boone, Jaishree Bhosle, Mike J. Tilby, John A. Hartley, Daniel Hochhauser
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (11): 3015–3023.
https://doi.org/10.1158/1535-7163.MCT-09-0219
Published: 10 November 2009
View articletitled, Involvement of the HER2 pathway in repair of DNA damage produced by chemotherapeutic agents
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Journal Articles

Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78

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Minal Kotecha, Jerome Kluza, Geoff Wells, C. Caroline O'Hare, Claudia Forni, Roberto Mantovani, Philip W. Howard, Peter Morris, David E. Thurston, John A. Hartley, Daniel Hochhauser
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2008) 7 (5): 1319–1328.
https://doi.org/10.1158/1535-7163.MCT-07-0475
Published: 15 May 2008
View articletitled, Inhibition of DNA binding of the NF-Y transcription factor by the pyrrolobenzodiazepine-polyamide conjugate GWL-78
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Journal Articles

Modulation of topoisomerase IIα expression by a DNA sequence-specific polyamide

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Daniel Hochhauser, Minal Kotecha, Caroline O'Hare, Peter J. Morris, Janet M. Hartley, Zarmeen Taherbhai, Dorothy Harris, Claudia Forni, Roberto Mantovani, Moses Lee, John A. Hartley
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (1): 346–354.
https://doi.org/10.1158/1535-7163.MCT-06-0503
Published: 19 January 2007
View articletitled, Modulation of topoisomerase IIα expression by a DNA sequence-specific polyamide
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Journal Articles

Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment

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Benjamin J. Friedmann, Martyn Caplin, Boris Savic, Tahir Shah, Christopher J. Lord, Alan Ashworth, John A. Hartley, Daniel Hochhauser
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2006) 5 (2): 209–218.
https://doi.org/10.1158/1535-7163.MCT-05-0239
Published: 27 February 2006
View articletitled, Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment
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