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Journal Articles

Targeting STAT3 with Proteolysis Targeting Chimeras and Next-Generation Antisense Oligonucleotides

Jamie V. Shiah, Jennifer R. Grandis, Daniel E. Johnson

Mol Cancer Ther (2021) 20 (2): 219–228.

https://doi.org/10.1158/1535-7163.MCT-20-0599

Published: 05 February 2021

View article titled, Targeting STAT3 with Proteolysis Targeting Chimeras and Next-Generation Antisense Oligonucleotides

Journal Articles

Pathway-Specific Genome Editing of PI3K/mTOR Tumor Suppressor Genes Reveals that PTEN Loss Contributes to Cetuximab Resistance in Head and Neck Cancer

Hiroki Izumi, Zhiyong Wang, Yusuke Goto, Toshinori Ando, Xingyu Wu, Xuefeng Zhang, Hua Li, Daniel E. Johnson, Jennifer R. Grandis, J. Silvio Gutkind

Mol Cancer Ther (2020) 19 (7): 1562–1571.

https://doi.org/10.1158/1535-7163.MCT-19-1036

Published: 02 July 2020

View article titled, Pathway-Specific Genome Editing of PI3K/mTOR Tumor Suppressor Genes Reveals that PTEN Loss Contributes to Cetuximab Resistance in Head and Neck Cancer

Includes: Supplementary data

Journal Articles

STAT3 Cyclic Decoy Demonstrates Robust Antitumor Effects in Non–Small Cell Lung Cancer

Christian Njatcha, Mariya Farooqui, Adam Kornberg, Daniel E. Johnson, Jennifer R. Grandis, Jill M. Siegfried

Mol Cancer Ther (2018) 17 (9): 1917–1926.

https://doi.org/10.1158/1535-7163.MCT-17-1194

Published: 04 September 2018

View article titled, STAT3 Cyclic Decoy Demonstrates Robust Antitumor Effects in Non–Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death

Changyou Li, Yan Zang, Malabika Sen, Rebecca J. Leeman-Neill, David SK. Man, Jennifer R. Grandis, Daniel E. Johnson

Mol Cancer Ther (2009) 8 (8): 2211–2220.

https://doi.org/10.1158/1535-7163.MCT-09-0327

Published: 14 August 2009

View article titled, Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death

Includes: Supplementary data

Journal Articles

Bortezomib induces apoptosis via Bim and Bik up-regulation and synergizes with cisplatin in the killing of head and neck squamous cell carcinoma cells

Changyou Li, Rongxiu Li, Jennifer R. Grandis, Daniel E. Johnson

Mol Cancer Ther (2008) 7 (6): 1647–1655.

https://doi.org/10.1158/1535-7163.MCT-07-2444

Published: 19 June 2008

View article titled, Bortezomib induces apoptosis via Bim and Bik up-regulation and synergizes with cisplatin in the killing of head and neck squamous cell carcinoma cells

Includes: Supplementary data

Journal Articles

Inhibition of Src family kinases enhances retinoic acid–induced gene expression and myeloid differentiation

Michelle B. Miranda, Robert L. Redner, Daniel E. Johnson

Mol Cancer Ther (2007) 6 (12): 3081–3090.

https://doi.org/10.1158/1535-7163.MCT-07-0514

Published: 18 December 2007

View article titled, Inhibition of Src family kinases enhances retinoic acid–induced gene expression and myeloid differentiation

Journal Articles

Involvement of cathepsin D in chemotherapy-induced cytochrome c release, caspase activation, and cell death

Lori Emert-Sedlak, Sanjeev Shangary, Asaf Rabinovitz, Michelle B. Miranda, Scott M. Delach, Daniel E. Johnson

Mol Cancer Ther (2005) 4 (5): 733–742.

https://doi.org/10.1158/1535-7163.MCT-04-0301

Published: 16 May 2005

View article titled, Involvement of cathepsin D in chemotherapy-induced cytochrome c release, caspase activation, and cell death

Journal Articles

(−)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X_L-mediated apoptosis resistance

Christopher L. Oliver, Michelle B. Miranda, Sanjeev Shangary, Stephanie Land, Shaomeng Wang, Daniel E. Johnson

Mol Cancer Ther (2005) 4 (1): 23–31.

https://doi.org/10.1158/1535-7163.23.4.1

Published: 18 January 2005

View article titled, (−)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-XL-mediated apoptosis resistance

Journal Articles

Sequence and helicity requirements for the proapoptotic activity of Bax BH3 peptides

Sanjeev Shangary, Christopher L. Oliver, Tommy S. Tillman, Michael Cascio, Daniel E. Johnson

Mol Cancer Ther (2004) 3 (11): 1343–1354.

https://doi.org/10.1158/1535-7163.1343.3.11

Published: 01 November 2004

View article titled, Sequence and helicity requirements for the proapoptotic activity of Bax BH3 peptides

NARROW

Targeting STAT3 with Proteolysis Targeting Chimeras and Next-Generation Antisense Oligonucleotides

Pathway-Specific Genome Editing of PI3K/mTOR Tumor Suppressor Genes Reveals that PTEN Loss Contributes to Cetuximab Resistance in Head and Neck Cancer

STAT3 Cyclic Decoy Demonstrates Robust Antitumor Effects in Non–Small Cell Lung Cancer

Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death

Bortezomib induces apoptosis via Bim and Bik up-regulation and synergizes with cisplatin in the killing of head and neck squamous cell carcinoma cells

Inhibition of Src family kinases enhances retinoic acid–induced gene expression and myeloid differentiation

Involvement of cathepsin D in chemotherapy-induced cytochrome c release, caspase activation, and cell death

(−)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X_L-mediated apoptosis resistance

Sequence and helicity requirements for the proapoptotic activity of Bax BH3 peptides

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