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Christopher P. Evans
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Journal Articles

Bioengineered BERA-Wnt5a siRNA Targeting Wnt5a/FZD2 Signaling Suppresses Advanced Prostate Cancer Tumor Growth and Enhances Enzalutamide Treatment

Shu Ning, Chengfei Liu, Wei Lou, Joy C. Yang, Alan P. Lombard, Leandro S. D'Abronzo, Neelu Batra, Ai-Ming Yu, Amy R. Leslie, Masuda Sharifi, Christopher P. Evans, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (10): 1594–1607.
https://doi.org/10.1158/1535-7163.MCT-22-0216
Published: 07 October 2022
View article titled, Bioengineered BERA-Wnt5a siRNA Targeting Wnt5a/FZD2 Signaling Suppresses Advanced Prostate Cancer Tumor Growth and Enhances Enzalutamide Treatment
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Includes: Supplementary data
Journal Articles

Olaparib-Induced Senescence Is Bypassed through G2–M Checkpoint Override in Olaparib-Resistant Prostate Cancer

Alan P. Lombard, Cameron M. Armstrong, Leandro S. D'Abronzo, Shu Ning, Amy R. Leslie, Masuda Sharifi, Wei Lou, Christopher P. Evans, Marc Dall'Era, Hong-Wu Chen, Xinbin Chen, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (4): 677–685.
https://doi.org/10.1158/1535-7163.MCT-21-0604
Published: 01 April 2022
View article titled, Olaparib-Induced Senescence Is Bypassed through G<sub>2</sub>–M Checkpoint Override in Olaparib-Resistant Prostate Cancer
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Journal Articles

Activation of the ABCB1 Amplicon in Docetaxel- and Cabazitaxel-Resistant Prostate Cancer Cells

Alan P. Lombard, Wei Lou, Cameron M. Armstrong, Leandro S. D'Abronzo, Shu Ning, Christopher P. Evans, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (10): 2061–2070.
https://doi.org/10.1158/1535-7163.MCT-20-0983
Published: 01 October 2021
View article titled, Activation of the <em>ABCB1</em> Amplicon in Docetaxel- and Cabazitaxel-Resistant Prostate Cancer Cells
Open the PDF for Activation of the <em>ABCB1</em> Amplicon in Docetaxel- and Cabazitaxel-Resistant Prostate Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Cross-Resistance Among Next-Generation Antiandrogen Drugs Through the AKR1C3/AR-V7 Axis in Advanced Prostate Cancer

Jinge Zhao, Shu Ning, Wei Lou, Joy C. Yang, Cameron M. Armstrong, Alan P. Lombard, Leandro S. D'Abronzo, Christopher P. Evans, Allen C. Gao, Chengfei Liu
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (8): 1708–1718.
https://doi.org/10.1158/1535-7163.MCT-20-0015
Published: 04 August 2020
View article titled, Cross-Resistance Among Next-Generation Antiandrogen Drugs Through the AKR1C3/AR-V7 Axis in Advanced Prostate Cancer
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Journal Articles

Therapeutic Targeting of MDR1 Expression by RORγ Antagonists Resensitizes Cross-Resistant CRPC to Taxane via Coordinated Induction of Cell Death Programs

Yongqiang Wang, Zenghong Huang, Christopher Z. Chen, Chengfei Liu, Christopher P. Evans, Allen C. Gao, Fangjian Zhou, Hong-Wu Chen
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (2): 364–374.
https://doi.org/10.1158/1535-7163.MCT-19-0327
Published: 06 February 2020
View article titled, Therapeutic Targeting of MDR1 Expression by RORγ Antagonists Resensitizes Cross-Resistant CRPC to Taxane via Coordinated Induction of Cell Death Programs
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Includes: Supplementary data
Journal Articles

AKR1C3 Promotes AR-V7 Protein Stabilization and Confers Resistance to AR-Targeted Therapies in Advanced Prostate Cancer

Chengfei Liu, Joy C. Yang, Cameron M. Armstrong, Wei Lou, Liangren Liu, Xiaomin Qiu, Binhao Zou, Alan P. Lombard, Leandro S. D'Abronzo, Christopher P. Evans, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (10): 1875–1886.
https://doi.org/10.1158/1535-7163.MCT-18-1322
Published: 01 October 2019
View article titled, AKR1C3 Promotes AR-V7 Protein Stabilization and Confers Resistance to AR-Targeted Therapies in Advanced Prostate Cancer
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Includes: Supplementary data
Journal Articles

GnRH Antagonists Have Direct Inhibitory Effects On Castration-Resistant Prostate Cancer Via Intracrine Androgen and AR-V7 Expression

Vito Cucchiara, Joy C. Yang, Chengfei Liu, Hans H. Adomat, Emma S. Tomlinson Guns, Martin E. Gleave, Allen C. Gao, Christopher P. Evans
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (10): 1811–1821.
https://doi.org/10.1158/1535-7163.MCT-18-1337
Published: 01 October 2019
View article titled, GnRH Antagonists Have Direct Inhibitory Effects On Castration-Resistant Prostate Cancer Via Intracrine Androgen and AR-V7 Expression
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Includes: Supplementary data
Journal Articles

Intra versus Inter Cross-resistance Determines Treatment Sequence between Taxane and AR-Targeting Therapies in Advanced Prostate Cancer

Alan P. Lombard, Liangren Liu, Vito Cucchiara, Chengfei Liu, Cameron M. Armstrong, Ruining Zhao, Joy C. Yang, Wei Lou, Christopher P. Evans, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (10): 2197–2205.
https://doi.org/10.1158/1535-7163.MCT-17-1269
Published: 01 October 2018
View article titled, Intra versus Inter Cross-resistance Determines Treatment Sequence between Taxane and AR-Targeting Therapies in Advanced Prostate Cancer
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Journal Articles

ABCB1 Mediates Cabazitaxel–Docetaxel Cross-Resistance in Advanced Prostate Cancer

Alan P. Lombard, Chengfei Liu, Cameron M. Armstrong, Vito Cucchiara, Xinwei Gu, Wei Lou, Christopher P. Evans, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (10): 2257–2266.
https://doi.org/10.1158/1535-7163.MCT-17-0179
Published: 02 October 2017
View article titled, ABCB1 Mediates Cabazitaxel–Docetaxel Cross-Resistance in Advanced Prostate Cancer
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Journal Articles

Niclosamide and Bicalutamide Combination Treatment Overcomes Enzalutamide- and Bicalutamide-Resistant Prostate Cancer

Chengfei Liu, Cameron M. Armstrong, Wei Lou, Alan P. Lombard, Vito Cucchiara, Xinwei Gu, Joy C. Yang, Nagalakshmi Nadiminty, Chong-xian Pan, Christopher P. Evans, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (8): 1521–1530.
https://doi.org/10.1158/1535-7163.MCT-16-0912
Published: 02 August 2017
View article titled, Niclosamide and Bicalutamide Combination Treatment Overcomes Enzalutamide- and Bicalutamide-Resistant Prostate Cancer
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Includes: Supplementary data
Journal Articles

Inhibition of AKR1C3 Activation Overcomes Resistance to Abiraterone in Advanced Prostate Cancer

Chengfei Liu, Cameron M. Armstrong, Wei Lou, Alan Lombard, Christopher P. Evans, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (1): 35–44.
https://doi.org/10.1158/1535-7163.MCT-16-0186
Published: 05 January 2017
View article titled, Inhibition of AKR1C3 Activation Overcomes Resistance to Abiraterone in Advanced Prostate Cancer
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Journal Articles

NF-κB2/p52:c-Myc:hnRNPA1 Pathway Regulates Expression of Androgen Receptor Splice Variants and Enzalutamide Sensitivity in Prostate Cancer

Nagalakshmi Nadiminty, Ramakumar Tummala, Chengfei Liu, Wei Lou, Christopher P. Evans, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (8): 1884–1895.
https://doi.org/10.1158/1535-7163.MCT-14-1057
Published: 05 August 2015
View article titled, NF-κB2/p52:c-Myc:hnRNPA1 Pathway Regulates Expression of Androgen Receptor Splice Variants and Enzalutamide Sensitivity in Prostate Cancer
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Includes: Supplementary data
Journal Articles

Inhibition of ABCB1 Expression Overcomes Acquired Docetaxel Resistance in Prostate Cancer

Yezi Zhu, Chengfei Liu, Nagalakshmi Nadiminty, Wei Lou, Ramakumar Tummala, Christopher P. Evans, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (9): 1829–1836.
https://doi.org/10.1158/1535-7163.MCT-13-0208
Published: 05 September 2013
View article titled, Inhibition of ABCB1 Expression Overcomes Acquired Docetaxel Resistance in Prostate Cancer
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Includes: Supplementary data
Journal Articles

NF-κB2/p52 Induces Resistance to Enzalutamide in Prostate Cancer: Role of Androgen Receptor and Its Variants

Nagalakshmi Nadiminty, Ramakumar Tummala, Chengfei Liu, Joy Yang, Wei Lou, Christopher P. Evans, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (8): 1629–1637.
https://doi.org/10.1158/1535-7163.MCT-13-0027
Published: 08 August 2013
View article titled, NF-κB2/p52 Induces Resistance to Enzalutamide in Prostate Cancer: Role of Androgen Receptor and Its Variants
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Includes: Supplementary data
Journal Articles

Effect of the Specific Src Family Kinase Inhibitor Saracatinib on Osteolytic Lesions Using the PC-3 Bone Model

Joy C. Yang, Lanfang Bai, Stanley Yap, Allen C. Gao, Hsing-Jien Kung, Christopher P. Evans
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2010) 9 (6): 1629–1637.
https://doi.org/10.1158/1535-7163.MCT-09-1058
Published: 09 June 2010
View article titled, Effect of the Specific Src Family Kinase Inhibitor Saracatinib on Osteolytic Lesions Using the PC-3 Bone Model
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Journal Articles

Interleukin-6 increases prostate cancer cells resistance to bicalutamide via TIF2

Siting Feng, Qizhu Tang, Meng Sun, Jae Yeon Chun, Christopher P. Evans, Allen C. Gao
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2009) 8 (3): 665–671.
https://doi.org/10.1158/1535-7163.MCT-08-0823
Published: 13 March 2009
View article titled, Interleukin-6 increases prostate cancer cells resistance to bicalutamide via TIF2
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