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Journal Articles

Correction: Combined Inhibition of NEDD8-activating Enzyme and mTOR Suppresses NF2 Loss–driven Tumorigenesis

Jonathan Cooper, Qingwen Xu, Lu Zhou, Milica Pavlovic, Virginia Ojeda, Kamalika Moulick, Elisa de Stanchina, John T. Poirier, Marjorie Zauderer, Charles M. Rudin, Matthias A. Karajannis, C. Oliver Hanemann, Filippo G. Giancotti

Mol Cancer Ther (2021) 20 (2): 450.

https://doi.org/10.1158/1535-7163.MCT-20-1027

Published: 05 February 2021

View article titled, Correction: Combined Inhibition of NEDD8-activating Enzyme and mTOR Suppresses NF2 Loss–driven Tumorigenesis

Journal Articles

Concurrent Targeting of Potential Cancer Stem Cells Regulating Pathways Sensitizes Lung Adenocarcinoma to Standard Chemotherapy

Masahiro Shibata, Akira Ooki, Yoshikuni Inokawa, Pritam Sadhukhan, M. Talha Ugurlu, Evgeny Izumchenko, Enrico Munari, Giuseppe Bogina, Charles M. Rudin, Edward Gabrielson, Anju Singh, Mohammad O. Hoque

Mol Cancer Ther (2020) 19 (10): 2175–2185.

https://doi.org/10.1158/1535-7163.MCT-20-0024

Published: 02 October 2020

View article titled, Concurrent Targeting of Potential Cancer Stem Cells Regulating Pathways Sensitizes Lung Adenocarcinoma to Standard Chemotherapy

Includes: Supplementary data

Journal Articles

Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss–Driven Tumorigenesis

Mol Cancer Ther (2017) 16 (8): 1693–1704.

https://doi.org/10.1158/1535-7163.MCT-16-0821

Published: 02 August 2017

View article titled, Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss–Driven Tumorigenesis

Includes: Supplementary data

Journal Articles

Repurposing the Antihelmintic Mebendazole as a Hedgehog Inhibitor

Andrew R. Larsen, Ren-Yuan Bai, Jon H. Chung, Alexandra Borodovsky, Charles M. Rudin, Gregory J. Riggins, Fred Bunz

Mol Cancer Ther (2015) 14 (1): 3–13.

https://doi.org/10.1158/1535-7163.MCT-14-0755-T

Published: 13 January 2015

View article titled, Repurposing the Antihelmintic Mebendazole as a Hedgehog Inhibitor

Includes: Supplementary data

Journal Articles

ERK Phosphorylation Is Predictive of Resistance to IGF-1R Inhibition in Small Cell Lung Cancer

Rebekah L. Zinn, Eric E. Gardner, Luigi Marchionni, Sara C. Murphy, Irina Dobromilskaya, Christine L. Hann, Charles M. Rudin

Mol Cancer Ther (2013) 12 (6): 1131–1139.

https://doi.org/10.1158/1535-7163.MCT-12-0618

Published: 09 June 2013

View article titled, ERK Phosphorylation Is Predictive of Resistance to IGF-1R Inhibition in Small Cell Lung Cancer

Includes: Supplementary data

Journal Articles

Poly(β-amino ester) Nanoparticle Delivery of TP53 Has Activity against Small Cell Lung Cancer In Vitro and In Vivo

Chandrashekhar D. Kamat, Ron B. Shmueli, Nick Connis, Charles M. Rudin, Jordan J. Green, Christine L. Hann

Mol Cancer Ther (2013) 12 (4): 405–415.

https://doi.org/10.1158/1535-7163.MCT-12-0956

Published: 08 April 2013

View article titled, Poly(β-amino ester) Nanoparticle Delivery of TP53 Has Activity against Small Cell Lung Cancer In Vitro and In Vivo

Includes: Supplementary data

Journal Articles

A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists

Venugopal Chenna, Chaoxin Hu, Dipankar Pramanik, Blake T. Aftab, Collins Karikari, Nathaniel R. Campbell, Seung-Mo Hong, Ming Zhao, Michelle A. Rudek, Saeed R. Khan, Charles M. Rudin, Anirban Maitra

Mol Cancer Ther (2012) 11 (1): 165–173.

https://doi.org/10.1158/1535-7163.MCT-11-0341

Published: 09 January 2012

View article titled, A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists

Includes: Supplementary data

Journal Articles

Abstract C147: Itraconazole side-chain analogs reveal a distinct structure-activity relationship for inhibition of hedgehog pathway signaling.

Blake T. Aftab, Wei Shi, Benjamin A. Nacev, Sarah Head, Jun O. Liu, Charles M. Rudin

Mol Cancer Ther (2011) 10 (11_Supplement): C147.

https://doi.org/10.1158/1535-7163.TARG-11-C147

Published: 12 November 2011

View article titled, Abstract C147: Itraconazole side-chain analogs reveal a distinct structure-activity relationship for inhibition of hedgehog pathway signaling.

Journal Articles

Akt up-regulation increases resistance to microtubule-directed chemotherapeutic agents through mammalian target of rapamycin

David J. VanderWeele, Rixin Zhou, Charles M. Rudin

Mol Cancer Ther (2004) 3 (12): 1605–1613.

https://doi.org/10.1158/1535-7163.1605.3.12

Published: 04 January 2005

View article titled, Akt up-regulation increases resistance to microtubule-directed chemotherapeutic agents through mammalian target of rapamycin

NARROW

Correction: Combined Inhibition of NEDD8-activating Enzyme and mTOR Suppresses NF2 Loss–driven Tumorigenesis

Concurrent Targeting of Potential Cancer Stem Cells Regulating Pathways Sensitizes Lung Adenocarcinoma to Standard Chemotherapy

Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss–Driven Tumorigenesis

Repurposing the Antihelmintic Mebendazole as a Hedgehog Inhibitor

ERK Phosphorylation Is Predictive of Resistance to IGF-1R Inhibition in Small Cell Lung Cancer

Poly(β-amino ester) Nanoparticle Delivery of TP53 Has Activity against Small Cell Lung Cancer In Vitro and In Vivo

A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists

Abstract C147: Itraconazole side-chain analogs reveal a distinct structure-activity relationship for inhibition of hedgehog pathway signaling.

Akt up-regulation increases resistance to microtubule-directed chemotherapeutic agents through mammalian target of rapamycin

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