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Carrie O'Connor
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Journal Articles

Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer

Adrianne Wallace-Povirk, Carrie O'Connor, Aamod S. Dekhne, Xun Bao, Md. Junayed Nayeen, Mathew Schneider, Jade M. Katinas, Jennifer Wong-Roushar, Seongho Kim, Lisa Polin, Jing Li, Jessica B. Back, Charles E. Dann, 3rd, Aleem Gangjee, Zhanjun Hou, Larry H. Matherly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2024) 23 (6): 809–822.
https://doi.org/10.1158/1535-7163.MCT-23-0550
Published: 04 June 2024
View article titled, Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer
Open the PDF for Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Correction: Novel Pyrrolo[3,2-d]Pyrimidine Compounds Target Mitochondrial and Cytosolic One-Carbon Metabolism with Broad-spectrum Antitumor Efficacy

Aamod S. Dekhne, Khushbu Shah, Gregory S. Ducker, Jade M. Katinas, Jennifer Wong-Roushar, Md. Junayed Nayeen, Arpit Doshi, Changwen Ning, Xun Bao, Josephine Frühauf, Jenney Liu, Adrianne Wallace-Povirk, Carrie O'Connor, Sijana H. Dzinic, Kathryn White, Juiwanna Kushner, Seongho Kim, Maik Hüttemann, Lisa Polin, Joshua D. Rabinowitz, Jing Li, Zhanjun Hou, Charles E. Dann, III, Aleem Gangjee, Larry H. Matherly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (2): 287.
https://doi.org/10.1158/1535-7163.MCT-22-0766
Published: 01 February 2023
View article titled, Correction: Novel Pyrrolo[3,2-<em>d</em>]Pyrimidine Compounds Target Mitochondrial and Cytosolic One-Carbon Metabolism with Broad-spectrum Antitumor Efficacy
Open the PDF for Correction: Novel Pyrrolo[3,2-<em>d</em>]Pyrimidine Compounds Target Mitochondrial and Cytosolic One-Carbon Metabolism with Broad-spectrum Antitumor Efficacy in another window
Journal Articles

Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy

Aamod S. Dekhne, Khushbu Shah, Gregory S. Ducker, Jade M. Katinas, Jennifer Wong-Roushar, Md. Junayed Nayeen, Arpit Doshi, Changwen Ning, Xun Bao, Josephine Frühauf, Jenney Liu, Adrianne Wallace-Povirk, Carrie O'Connor, Sijana H. Dzinic, Kathryn White, Juiwanna Kushner, Seongho Kim, Maik Hüttemann, Lisa Polin, Joshua D. Rabinowitz, Jing Li, Zhanjun Hou, Charles E. Dann, III, Aleem Gangjee, Larry H. Matherly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (10): 1787–1799.
https://doi.org/10.1158/1535-7163.MCT-19-0037
Published: 01 October 2019
View article titled, Novel Pyrrolo[3,2-<em>d</em>]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy
Open the PDF for Novel Pyrrolo[3,2-<em>d</em>]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy in another window
Includes: Supplementary data
Journal Articles

Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]pyrimidine Antifolates

Zhanjun Hou, Leda Gattoc, Carrie O'Connor, Si Yang, Adrianne Wallace-Povirk, Christina George, Steve Orr, Lisa Polin, Kathryn White, Juiwanna Kushner, Robert T. Morris, Aleem Gangjee, Larry H. Matherly
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (5): 819–830.
https://doi.org/10.1158/1535-7163.MCT-16-0444
Published: 02 May 2017
View article titled, Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-<em>d</em>]pyrimidine Antifolates
Open the PDF for Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-<em>d</em>]pyrimidine Antifolates in another window
Includes: Supplementary data