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Bruno Bockorny
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Journal Articles

First Results of Migoprotafib, a Potent and Highly Selective Src Homology-2 Domain–Containing Phosphatase 2 Inhibitor in Patients with Advanced Solid Tumors

Melissa L. Johnson, Beni B. Wolf, Judy S. Wang, Alexander Philipovskiy, Geoffrey I. Shapiro, Bruno Bockorny, Wei Guo, Jinshan Shen, Kai Yu Jen, MaryBeth LeRose, Tamieka Lauz Hunter, Mahesh Padval, Oleg Schmidt-Kittler, Namrata Bhatia, Sarita Dubey, Julia Suchomel, Johanna C. Bendell, Shekeab Jauhari, Jennifer Eng-Wong, Jessica J. Lin
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther OF1–OF8.
https://doi.org/10.1158/1535-7163.MCT-24-0466
Published: 31 December 2024
View article titled, First Results of Migoprotafib, a Potent and Highly Selective Src Homology-2 Domain–Containing Phosphatase 2 Inhibitor in Patients with Advanced Solid Tumors
Open the PDF for First Results of Migoprotafib, a Potent and Highly Selective Src Homology-2 Domain–Containing Phosphatase 2 Inhibitor in Patients with Advanced Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Discovery of New Targets to Control Metastasis in Pancreatic Cancer by Single-cell Transcriptomics Analysis of Circulating Tumor Cells

Spas Dimitrov-Markov, Javier Perales-Patón, Bruno Bockorny, Ana Dopazo, Manuel Muñoz, Natalia Baños, Victoria Bonilla, Camino Menendez, Yolanda Duran, Ling Huang, Sofia Perea, Senthil K. Muthuswamy, Fatima Al-Shahrour, Pedro P. Lopez-Casas, Manuel Hidalgo
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2020) 19 (8): 1751–1760.
https://doi.org/10.1158/1535-7163.MCT-19-1166
Published: 04 August 2020
View article titled, Discovery of New Targets to Control Metastasis in Pancreatic Cancer by Single-cell Transcriptomics Analysis of Circulating Tumor Cells
Open the PDF for Discovery of New Targets to Control Metastasis in Pancreatic Cancer by Single-cell Transcriptomics Analysis of Circulating Tumor Cells in another window
Includes: Supplementary data
Journal Articles

RAS–MAPK Reactivation Facilitates Acquired Resistance in FGFR1-Amplified Lung Cancer and Underlies a Rationale for Upfront FGFR–MEK Blockade

Bruno Bockorny, Maria Rusan, Wankun Chen, Rachel G. Liao, Yvonne Li, Federica Piccioni, Jun Wang, Li Tan, Aaron R. Thorner, Tianxia Li, Yanxi Zhang, Changhong Miao, Therese Ovesen, Geoffrey I. Shapiro, David J. Kwiatkowski, Nathanael S. Gray, Matthew Meyerson, Peter S. Hammerman, Adam J. Bass
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (7): 1526–1539.
https://doi.org/10.1158/1535-7163.MCT-17-0464
Published: 01 July 2018
View article titled, RAS–MAPK Reactivation Facilitates Acquired Resistance in <em>FGFR1</em>-Amplified Lung Cancer and Underlies a Rationale for Upfront FGFR–MEK Blockade
Open the PDF for RAS–MAPK Reactivation Facilitates Acquired Resistance in <em>FGFR1</em>-Amplified Lung Cancer and Underlies a Rationale for Upfront FGFR–MEK Blockade in another window
Includes: Supplementary data