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Brian J. Druker
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Journal Articles

Luxeptinib (CG-806) Targets FLT3 and Clusters of Kinases Operative in Acute Myeloid Leukemia

Open Access
William G. Rice, Stephen B. Howell, Hongying Zhang, Nasrin Rastgoo, Andrea Local, Stephen E. Kurtz, Pierrette Lo, Daniel Bottomly, Beth Wilmot, Shannon K. McWeeney, Brian J. Druker, Jeffrey W. Tyner
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2022) 21 (7): 1125–1135.
https://doi.org/10.1158/1535-7163.MCT-21-0832
Published: 05 July 2022
View articletitled, Luxeptinib (CG-806) Targets FLT3 and Clusters of Kinases Operative in Acute Myeloid Leukemia
Open the PDF for Luxeptinib (CG-806) Targets FLT3 and Clusters of Kinases Operative in Acute Myeloid Leukemia in another window
Includes: Supplementary data
Journal Articles

Potent Activity of Ponatinib (AP24534) in Models of FLT3-Driven Acute Myeloid Leukemia and Other Hematologic Malignancies

Free
Joseph M. Gozgit, Matthew J. Wong, Scott Wardwell, Jeffrey W. Tyner, Marc M. Loriaux, Qurish K. Mohemmad, Narayana I. Narasimhan, William C. Shakespeare, Frank Wang, Brian J. Druker, Tim Clackson, Victor M. Rivera
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (6): 1028–1035.
https://doi.org/10.1158/1535-7163.MCT-10-1044
Published: 08 June 2011
View articletitled, Potent Activity of Ponatinib (AP24534) in Models of FLT3-Driven Acute Myeloid Leukemia and Other Hematologic Malignancies
Open the PDF for Potent Activity of Ponatinib (AP24534) in Models of FLT3-Driven Acute Myeloid Leukemia and Other Hematologic Malignancies in another window
Journal Articles

Progressive loss of epidermal growth factor receptor in a subpopulation of breast cancers: implications in target-directed therapeutics

Free
Lee-Yee Choong, Simin Lim, Marie Chiew-Shia Loh, Xiaohui Man, Yunhao Chen, Weiyi Toy, Mengfei Pan, Chien-Shing Chen, Anuradha Poonepalli, M. Prakash Hande, Puay-Hoon Tan, Manuel Salto-Tellez, Chow-Yin Wong, Nilesh Shah, Brian J. Druker, Yoon-Pin Lim
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2007) 6 (11): 2828–2842.
https://doi.org/10.1158/1535-7163.MCT-06-0809
Published: 19 November 2007
View articletitled, Progressive loss of epidermal growth factor receptor in a subpopulation of breast cancers: implications in target-directed therapeutics
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Journal Articles

Phosphoproteomic fingerprinting of epidermal growth factor signaling and anticancer drug action in human tumor cells

Free
Yoon-Pin Lim, Lang-Shi Diong, Robert Qi, Brian J. Druker, Richard J. Epstein
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (12): 1369–1377.
Published: 05 January 2004
View articletitled, Phosphoproteomic fingerprinting of epidermal growth factor signaling and anticancer drug action in human tumor cells
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Journal Articles

Overcoming Resistance to Imatinib by Combining Targeted Agents

Free
Brian J. Druker
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2003) 2 (3): 225–226.
Published: 01 March 2003
View articletitled, Overcoming Resistance to Imatinib by Combining Targeted Agents
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