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Blake T. Aftab
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Journal Articles

Abstract C117: Preclinical characterization of allogeneic CAR γδ T Cell therapy for prostate cancer targeting a novel dimeric epitope on PSMA

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Nitya S. Ramadoss, Elizabeth Speltz, Tonya Capillo, Erika Meaddough, Katherine Wang, Natalia Friedland, Jonathan Wong, Alexander G Teague, Aruna Azameera, Smitha Rao Yelaguli Gundurao, Ramandeep Kaur, Morgan Smith-Boeck, Michael Salum, Yvan Chanthery, Shon Green, Marissa Herrman, Kevin P Nishimoto, Blake T Aftab, Arun Bhat
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2023) 22 (12_Supplement): C117.
https://doi.org/10.1158/1535-7163.TARG-23-C117
Published: 01 December 2023
View articletitled, Abstract C117: Preclinical characterization of allogeneic CAR γδ T Cell therapy for prostate cancer targeting a novel dimeric epitope on PSMA
Journal Articles

The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma

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Ronan Le Moigne, Blake T. Aftab, Stevan Djakovic, Eugen Dhimolea, Eduardo Valle, Megan Murnane, Emily M. King, Ferdie Soriano, Mary-Kamala Menon, Zhi Yong Wu, Stephen T. Wong, Grace J. Lee, Bing Yao, Arun P. Wiita, Christine Lam, Julie Rice, Jinhai Wang, Marta Chesi, P. Leif Bergsagel, Marianne Kraus, Christoph Driessen, Szerenke Kiss Von Soly, F. Michael Yakes, David Wustrow, Laura Shawver, Han-Jie Zhou, Thomas G. Martin, III, Jeffrey L. Wolf, Constantine S. Mitsiades, Daniel J. Anderson, Mark Rolfe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (11): 2375–2386.
https://doi.org/10.1158/1535-7163.MCT-17-0233
Published: 01 November 2017
View articletitled, The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma
Open the PDF for The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma in another window
Includes: Supplementary data
Journal Articles

Validation of the Hsp70–Bag3 Protein–Protein Interaction as a Potential Therapeutic Target in Cancer

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Xiaokai Li, Teresa Colvin, Jennifer N. Rauch, Diego Acosta-Alvear, Martin Kampmann, Bryan Dunyak, Byron Hann, Blake T. Aftab, Megan Murnane, Min Cho, Peter Walter, Jonathan S. Weissman, Michael Y. Sherman, Jason E. Gestwicki
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (3): 642–648.
https://doi.org/10.1158/1535-7163.MCT-14-0650
Published: 09 March 2015
View articletitled, Validation of the Hsp70–Bag3 Protein–Protein Interaction as a Potential Therapeutic Target in Cancer
Open the PDF for Validation of the Hsp70–Bag3 Protein–Protein Interaction as a Potential Therapeutic Target in Cancer in another window
Includes: Supplementary data
Journal Articles

A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists

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Venugopal Chenna, Chaoxin Hu, Dipankar Pramanik, Blake T. Aftab, Collins Karikari, Nathaniel R. Campbell, Seung-Mo Hong, Ming Zhao, Michelle A. Rudek, Saeed R. Khan, Charles M. Rudin, Anirban Maitra
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2012) 11 (1): 165–173.
https://doi.org/10.1158/1535-7163.MCT-11-0341
Published: 09 January 2012
View articletitled, A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists
Open the PDF for A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists in another window
Includes: Supplementary data
Journal Articles

Abstract C147: Itraconazole side-chain analogs reveal a distinct structure-activity relationship for inhibition of hedgehog pathway signaling.

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Blake T. Aftab, Wei Shi, Benjamin A. Nacev, Sarah Head, Jun O. Liu, Charles M. Rudin
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2011) 10 (11_Supplement): C147.
https://doi.org/10.1158/1535-7163.TARG-11-C147
Published: 12 November 2011
View articletitled, Abstract C147: Itraconazole side-chain analogs reveal a distinct structure-activity relationship for inhibition of hedgehog pathway signaling.