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Journal Articles

Piperlongumine Chemosensitizes Tumor Cells through Interaction with Cysteine 179 of IκBα Kinase, Leading to Suppression of NF-κB–Regulated Gene Products

Jia Gang Han, Subash C. Gupta, Sahdeo Prasad, Bharat B. Aggarwal

Mol Cancer Ther (2014) 13 (10): 2422–2435.

DOI: https://doi.org/10.1158/1535-7163.MCT-14-0171

Published: 02 October 2014

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Journal Articles

Plumbagin Inhibits Osteoclastogenesis and Reduces Human Breast Cancer-Induced Osteolytic Bone Metastasis in Mice through Suppression of RANKL Signaling

Bokyung Sung, Babatunde Oyajobi, Bharat B. Aggarwal

Mol Cancer Ther (2012) 11 (2): 350–359.

DOI: https://doi.org/10.1158/1535-7163.MCT-11-0731

Published: 08 February 2012

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Journal Articles

γ-Tocotrienol Promotes TRAIL-Induced Apoptosis through Reactive Oxygen Species/Extracellular Signal-Regulated Kinase/p53–Mediated Upregulation of Death Receptors

Ramaswamy Kannappan, Jayaraj Ravindran, Sahdeo Prasad, Bokyung Sung, Vivek R. Yadav, Simone Reuter, Madan M. Chaturvedi, Bharat B. Aggarwal

Mol Cancer Ther (2010) 9 (8): 2196–2207.

DOI: https://doi.org/10.1158/1535-7163.MCT-10-0277

Published: 09 August 2010

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Includes: Supplementary data

Journal Articles

A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivo

Mol Cancer Ther (2010) 9 (5): 1136–1146.

DOI: https://doi.org/10.1158/1535-7163.MCT-09-1145

Published: 09 May 2010

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Includes: Supplementary data

Journal Articles

Garcinol Potentiates TRAIL-Induced Apoptosis through Modulation of Death Receptors and Antiapoptotic Proteins

Sahdeo Prasad, Jayaraj Ravindran, Bokyung Sung, Manoj K. Pandey, Bharat B. Aggarwal

Mol Cancer Ther (2010) 9 (4): 856–868.

DOI: https://doi.org/10.1158/1535-7163.MCT-09-1113

Published: 07 April 2010

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Includes: Supplementary data

Journal Articles

Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model

Bokyung Sung, Ajaikumar B. Kunnumakkara, Gautam Sethi, Preetha Anand, Sushovan Guha, Bharat B. Aggarwal

Mol Cancer Ther (2009) 8 (4): 959–970.

DOI: https://doi.org/10.1158/1535-7163.MCT-08-0905

Published: 16 April 2009

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Journal Articles

Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-κB pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis

Ajaikumar B. Kunnumakkara, Haruyo Ichikawa, Preetha Anand, Chiramel J. Mohankumar, Padmanabhan S. Hema, Mangalam S. Nair, Bharat B. Aggarwal

Mol Cancer Ther (2008) 7 (10): 3306–3317.

DOI: https://doi.org/10.1158/1535-7163.MCT-08-0432

Published: 13 October 2008

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Includes: Supplementary data

Journal Articles

Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways

Tingfang Yi, Sung-Gook Cho, Zhengfang Yi, Xiufeng Pang, Melissa Rodriguez, Ying Wang, Gautam Sethi, Bharat B. Aggarwal, Mingyao Liu

Mol Cancer Ther (2008) 7 (7): 1789–1796.

DOI: https://doi.org/10.1158/1535-7163.MCT-08-0124

Published: 21 July 2008

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Journal Articles

Pinitol targets nuclear factor-κB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis

Gautam Sethi, Kwang Seok Ahn, Bokyung Sung, Bharat B. Aggarwal

Mol Cancer Ther (2008) 7 (6): 1604–1614.

DOI: https://doi.org/10.1158/1535-7163.MCT-07-2424

Published: 19 June 2008

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Journal Articles

Identification of a novel blocker of IκBα kinase activation that enhances apoptosis and inhibits proliferation and invasion by suppressing nuclear factor-κB

Bokyung Sung, Manoj K. Pandey, Yuki Nakajima, Hiroshi Nishida, Tetsuya Konishi, Madan M. Chaturvedi, Bharat B. Aggarwal

Mol Cancer Ther (2008) 7 (1): 191–201.

DOI: https://doi.org/10.1158/1535-7163.MCT-07-0406

Published: 17 January 2008

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Journal Articles

Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-κB and nuclear factor-κB–regulated gene products in IFN-α–sensitive and IFN-α–resistant human bladder cancer cells

Ashish M. Kamat, Gautam Sethi, Bharat B. Aggarwal

Mol Cancer Ther (2007) 6 (3): 1022–1030.

DOI: https://doi.org/10.1158/1535-7163.MCT-06-0545

Published: 15 March 2007

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Journal Articles

Pretherapy nuclear factor-κB status, chemoradiation resistance, and metastatic progression in esophageal carcinoma

Julie G. Izzo, Arlene M. Correa, Tsung-Teh Wu, Usha Malhotra, Clifford K.S. Chao, Rajyalakshmi Luthra, Joe Ensor, Alexander Dekovich, Zhongxing Liao, Walter N. Hittelman, Bharat B. Aggarwal, Jaffer A. Ajani

Mol Cancer Ther (2006) 5 (11): 2844–2850.

DOI: https://doi.org/10.1158/1535-7163.MCT-06-0351

Published: 22 November 2006

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Journal Articles

Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-κB (NF-κB) activation and NF-κB–regulated gene expression

Haruyo Ichikawa, Yasunari Takada, Shishir Shishodia, Bolleddula Jayaprakasam, Muraleedharan G. Nair, Bharat B. Aggarwal

Mol Cancer Ther (2006) 5 (6): 1434–1445.

DOI: https://doi.org/10.1158/1535-7163.MCT-06-0096

Published: 03 July 2006

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NARROW

Piperlongumine Chemosensitizes Tumor Cells through Interaction with Cysteine 179 of IκBα Kinase, Leading to Suppression of NF-κB–Regulated Gene Products

Plumbagin Inhibits Osteoclastogenesis and Reduces Human Breast Cancer-Induced Osteolytic Bone Metastasis in Mice through Suppression of RANKL Signaling

γ-Tocotrienol Promotes TRAIL-Induced Apoptosis through Reactive Oxygen Species/Extracellular Signal-Regulated Kinase/p53–Mediated Upregulation of Death Receptors

A Novel Small-Molecule Inhibitor of Protein Kinase D Blocks Pancreatic Cancer Growth In vitro and In vivo

Garcinol Potentiates TRAIL-Induced Apoptosis through Modulation of Death Receptors and Antiapoptotic Proteins

Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model

Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-κB pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis

Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways

Pinitol targets nuclear factor-κB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis

Identification of a novel blocker of IκBα kinase activation that enhances apoptosis and inhibits proliferation and invasion by suppressing nuclear factor-κB

Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-κB and nuclear factor-κB–regulated gene products in IFN-α–sensitive and IFN-α–resistant human bladder cancer cells

Pretherapy nuclear factor-κB status, chemoradiation resistance, and metastatic progression in esophageal carcinoma

Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-κB (NF-κB) activation and NF-κB–regulated gene expression

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