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Benjamin Besse
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Journal Articles

Molecular Characteristics of Repotrectinib That Enable Potent Inhibition of TRK Fusion Proteins and Resistant Mutations

Brion W. Murray, Evan Rogers, Dayong Zhai, Wei Deng, Xi Chen, Paul A. Sprengeler, Xin Zhang, Armin Graber, Siegfried H. Reich, Shanna Stopatschinskaja, Benjamin Solomon, Benjamin Besse, Alexander Drilon
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12): 2446–2456.
DOI: https://doi.org/10.1158/1535-7163.MCT-21-0632
Published: 03 December 2021
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Includes: Supplementary data
Journal Articles

Abstract P225: Preliminary interim data of elzovantinib (TPX-0022), a novel inhibitor of MET/SRC/CSF1R, in patients with advanced solid tumors harboring genetic alterations in MET: Update from the Phase 1 SHIELD-1 trial

David S. Hong, Daniel Catenacci, Lyudmila Bazhenova, Byoung Chul Cho, Mariano Ponz-Sarvise, Rebecca Heist, Victor Moreno, Gerald Falchook, Viola W. Zhu, Aurélie Swalduz, Benjamin Besse, Dong-Wan Kim, Shinkyo Yoon, Xiuning Le, Tingting Zhao, Alysha Kadva, Zachary Zimmerman, Jeeyun Lee
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12_Supplement): P225.
DOI: https://doi.org/10.1158/1535-7163.TARG-21-P225
Published: 01 December 2021
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Journal Articles

Abstract P02-01: Repotrectinib in patients with NTRK fusion-positive advanced solid tumors: update from the registrational phase 2 TRIDENT-1 trial

Benjamin Besse, Christina Baik, Christoph Springfeld, Alice Hervieu, Victor Moreno, Lyudmila Bazhenova, Jessica J. Lin, D. Ross Camidge, Benjamin Solomon, Vamsidhar Velcheti, Anthonie J. van der Wekken, Enriqueta Felip, Dipesh Uprety, Denise Trone, Shanna Stopatschinskaja, Byoung Chul Cho, Alexander Drilon
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (12_Supplement): P02-01.
DOI: https://doi.org/10.1158/1535-7163.TARG-21-P02-01
Published: 01 December 2021
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Journal Articles

Abstract B043: Identification of secreted PD-L1 variants as a decoy of PD-L1 blockade antibody mediating the therapeutic resistance

Bo Gong, Kazuma Kiyotani, Seiji Sakata, Ken Takahashi, Seiji Nagano, Shun Kumehara, Satoko Baba, Benjamin Besse, Noriko Yanagitani, Luc Friboulet, Makoto Nishio, Kengo Takeuchi, Hiroshi Kawamoto, Naoya Fujita, Ryohei Katayama
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): B043.
DOI: https://doi.org/10.1158/1535-7163.TARG-19-B043
Published: 01 December 2019
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Journal Articles

Abstract B7: Assessing the clinical applications of ctDNA in patients with advanced stage metastatic cancer using our enhanced TAm-Seq platform

Sarah K. Smalley, Davina Gale, Andrew RJ Lawson, Jordi Remon-Masip, Esperanza Perez, Michelle Pugh, Karen Howarth, Mehdi Touat, Jean-Charles Soria, Antoine Hollebecque, Benjamin Besse, Tim Forshew, Vincent Plagnol, Ludovic Lacroix, Nitzan Rosenfeld
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): B7.
DOI: https://doi.org/10.1158/1535-7163.TARG-15-B7
Published: 01 December 2015
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Journal Articles

Abstract A51: Phase I, safety, tolerability and preliminary efficacy study of Tremelimumab (Trem) in combination with Gefitinib (Gef) in EGFR-mutant (EGFR-mut) NSCLC (GEFTREM)

David Planchard, Fabrice Barlesi, Carlos Gomez-Roca, Julien Mazieres, Andrea Varga, Laurent Greillier, Nathalie Chaput-Gras, Emilie Lanoy, Cedric Parlavecchio, Katty Malekzadeh, Maud Ngocamus, Sarah ZAHI, Benjamin Besse, Audrey Poterie, Jean-Charles Soria
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (12_Supplement_2): A51.
DOI: https://doi.org/10.1158/1535-7163.TARG-15-A51
Published: 01 December 2015
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Journal Articles

Abstract A130: Joint cell-line (CCLE, Sanger) and patient (TCGA) modeling of drug sensitivity reveals novel molecular biomarkers for targeted therapy and conventional chemotherapy.

Charles Ferté, Elias Chaibub Neto, Chong Sun, Cecilia Noecker, Frederic Commo, Olga Nikolova, In Sock Jang, Mehmet Gonen, Benjamin Besse, Fabrice André, Eric Angevin, Ludovic Lacroix, Clement Mazoyer, Antoine Hollebecque, Christophe Massard, Adam Margolin, Roderick Beijersbergen, Stephen Friend, Rene Bernards, Jean-Charles Soria, Justin Guinney
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): A130.
DOI: https://doi.org/10.1158/1535-7163.TARG-13-A130
Published: 01 November 2013
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