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Journal Articles

Anticancer Efficacy of KRAS^G12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRAS^G12C-Mutant Pancreatic and Lung Cancers

Mol Cancer Ther (2023) 22 (12): 1422–1433.

https://doi.org/10.1158/1535-7163.MCT-23-0251

Published: 01 December 2023

View article titled, Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers

Includes: Supplementary data

Journal Articles

Abstract LB_B26: Efficacy and tolerability of a novel pan-RAS inhibitor with a unique mechanism of selectivity in mouse models of pancreatic cancer

Adam B Keeton, Yulia Y Maxuitenko, Jeremy B Foote, Chung-Hui Huang, Kristy L Berry, Khalda Fadlalla, Ganji P Nagaraju, Bandi DS Reddy, Xi Chen, Bassel F El-Rayes, Donald J Buchsbaum, Gary A Piazza

Mol Cancer Ther (2023) 22 (12_Supplement): LB_B26.

https://doi.org/10.1158/1535-7163.TARG-23-LB_B26

Published: 01 December 2023

View article titled, Abstract LB_B26: Efficacy and tolerability of a novel pan-RAS inhibitor with a unique mechanism of selectivity in mouse models of pancreatic cancer

Journal Articles

PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus

Gabriel B. Mpilla, Md. Hafiz Uddin, Mohammed N. Al-Hallak, Amro Aboukameel, Yiwei Li, Steve H. Kim, Rafic Beydoun, Gregory Dyson, Erkan Baloglu, William T. Senapedis, Yosef Landesman, Kay-Uwe Wagner, Nerissa T. Viola, Bassel F. El-Rayes, Philip A. Philip, Ramzi M. Mohammad, Asfar S. Azmi

Mol Cancer Ther (2021) 20 (10): 1836–1845.

https://doi.org/10.1158/1535-7163.MCT-20-1105

Published: 01 October 2021

View article titled, PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus

Includes: Supplementary data

Journal Articles

Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer

Yuchen Zhang, Michael B. Ware, Mohammad Y. Zaidi, Amanda N. Ruggieri, Brian M. Olson, Hannah Komar, Matthew R. Farren, Ganji Purnachandra Nagaraju, Chao Zhang, Zhengjia Chen, Juan M. Sarmiento, Rafi Ahmed, Shishir K. Maithel, Bassel F. El-Rayes, Gregory B. Lesinski

Mol Cancer Ther (2021) 20 (1): 150–160.

https://doi.org/10.1158/1535-7163.MCT-19-0911

Published: 05 January 2021

View article titled, Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer

Includes: Supplementary data

Journal Articles

Apoptosis-inducing effect of erlotinib is potentiated by 3,3′-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer

Shadan Ali, Sanjeev Banerjee, Aamir Ahmad, Bassel F. El-Rayes, Philip A. Philip, Fazlul H. Sarkar

Mol Cancer Ther (2008) 7 (6): 1708–1719.

https://doi.org/10.1158/1535-7163.MCT-08-0354

Published: 19 June 2008

View article titled, Apoptosis-inducing effect of erlotinib is potentiated by 3,3′-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer

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Anticancer Efficacy of KRAS^G12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRAS^G12C-Mutant Pancreatic and Lung Cancers

Abstract LB_B26: Efficacy and tolerability of a novel pan-RAS inhibitor with a unique mechanism of selectivity in mouse models of pancreatic cancer

PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus

Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer

Apoptosis-inducing effect of erlotinib is potentiated by 3,3′-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer

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AACR Journals

Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers

Abstract LB_B26: Efficacy and tolerability of a novel pan-RAS inhibitor with a unique mechanism of selectivity in mouse models of pancreatic cancer

PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus

Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer

Apoptosis-inducing effect of erlotinib is potentiated by 3,3′-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer

Email alerts

AACR Journals

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Anticancer Efficacy of KRAS^G12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRAS^G12C-Mutant Pancreatic and Lung Cancers