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Andrea Local
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Journal Articles

Luxeptinib (CG-806) targets FLT3 and clusters of kinases operative in acute myeloid leukemia

William G. Rice, Stephen B. Howell, Hongying Zhang, Nasrin Rastgoo, Andrea Local, Stephen E. Kurtz, Pierrette Lo, Daniel Bottomly, Beth Wilmot, Shannon K. McWeeney, Brian J. Druker, Jeffrey W. Tyner
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther molcanther.0832.2021.
DOI: https://doi.org/10.1158/1535-7163.MCT-21-0832
Published: 02 May 2022
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Includes: Supplementary data
Journal Articles

APTO-253 Stabilizes G-quadruplex DNA, Inhibits MYC Expression, and Induces DNA Damage in Acute Myeloid Leukemia Cells

Andrea Local, Hongying Zhang, Khalid D. Benbatoul, Peter Folger, Xia Sheng, Cheng-Yu Tsai, Stephen B. Howell, William G. Rice
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2018) 17 (6): 1177–1186.
DOI: https://doi.org/10.1158/1535-7163.MCT-17-1209
Published: 31 May 2018
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Includes: Supplementary data
Journal Articles

APTO-253 Is a New Addition to the Repertoire of Drugs that Can Exploit DNA BRCA1/2 Deficiency

Cheng-Yu Tsai, Si Sun, Hongying Zhang, Andrea Local, Yongxuan Su, Larry A. Gross, William G. Rice, Stephen B. Howell
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2018) 17 (6): 1167–1176.
DOI: https://doi.org/10.1158/1535-7163.MCT-17-0834
Published: 31 May 2018
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Includes: Supplementary data