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Journal Articles

Anticancer Efficacy of KRAS^G12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRAS^G12C-Mutant Pancreatic and Lung Cancers

Mol Cancer Ther (2023) 22 (12): 1422–1433.

https://doi.org/10.1158/1535-7163.MCT-23-0251

Published: 01 December 2023

View article titled, Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers

Includes: Supplementary data

Journal Articles

PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus

Gabriel B. Mpilla, Md. Hafiz Uddin, Mohammed N. Al-Hallak, Amro Aboukameel, Yiwei Li, Steve H. Kim, Rafic Beydoun, Gregory Dyson, Erkan Baloglu, William T. Senapedis, Yosef Landesman, Kay-Uwe Wagner, Nerissa T. Viola, Bassel F. El-Rayes, Philip A. Philip, Ramzi M. Mohammad, Asfar S. Azmi

Mol Cancer Ther (2021) 20 (10): 1836–1845.

https://doi.org/10.1158/1535-7163.MCT-20-1105

Published: 01 October 2021

View article titled, PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus

Includes: Supplementary data

Journal Articles

Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma

Amro Aboukameel, Irfana Muqbil, William Senapedis, Erkan Baloglu, Yosef Landesman, Sharon Shacham, Michael Kauffman, Philip A. Philip, Ramzi M. Mohammad, Asfar S. Azmi

Mol Cancer Ther (2017) 16 (1): 76–87.

https://doi.org/10.1158/1535-7163.MCT-16-0205

Published: 05 January 2017

View article titled, Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma

Includes: Supplementary data

Journal Articles

A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo

Fardokht Abulwerdi, Chenzhong Liao, Meilan Liu, Asfar S. Azmi, Amro Aboukameel, Ahmed S.A. Mady, Thippeswamy Gulappa, Tomasz Cierpicki, Scott Owens, Tao Zhang, Duxin Sun, Jeanne A. Stuckey, Ramzi M. Mohammad, Zaneta Nikolovska-Coleska

Mol Cancer Ther (2014) 13 (3): 565–575.

https://doi.org/10.1158/1535-7163.MCT-12-0767

Published: 09 March 2014

View article titled, A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo

Includes: Supplementary data

Journal Articles

Garcinol Regulates EMT and Wnt Signaling Pathways In Vitro and In Vivo, Leading to Anticancer Activity against Breast Cancer Cells

Aamir Ahmad, Sanila H. Sarkar, Bassam Bitar, Shadan Ali, Amro Aboukameel, Seema Sethi, Yiwei Li, Bin Bao, Dejuan Kong, Sanjeev Banerjee, Subhash B. Padhye, Fazlul H. Sarkar

Mol Cancer Ther (2012) 11 (10): 2193–2201.

https://doi.org/10.1158/1535-7163.MCT-12-0232-T

Published: 09 October 2012

View article titled, Garcinol Regulates EMT and Wnt Signaling Pathways In Vitro and In Vivo, Leading to Anticancer Activity against Breast Cancer Cells

Journal Articles

Adamantyl-Substituted Retinoid-Related Molecules Induce Apoptosis in Human Acute Myelogenous Leukemia Cells

Lulu Farhana, Marcia I. Dawson, Zebin Xia, Amro Aboukameel, Liping Xu, Gang Liu, Jayanta K. Das, James Hatfield, Edi Levi, Ramzi Mohammad, Joseph A. Fontana

Mol Cancer Ther (2010) 9 (11): 2903–2913.

https://doi.org/10.1158/1535-7163.MCT-10-0546

Published: 09 November 2010

View article titled, Adamantyl-Substituted Retinoid-Related Molecules Induce Apoptosis in Human Acute Myelogenous Leukemia Cells

Journal Articles

ErbB-Inhibitory Protein: A Modified Ectodomain of Epidermal Growth Factor Receptor Synergizes with Dasatinib to Inhibit Growth of Breast Cancer Cells

Jyoti Nautiyal, Yingjie Yu, Amro Aboukameel, Shailender S. Kanwar, Jayanta K. Das, Jianhua Du, Bhaumik B. Patel, Fazlul H. Sarkar, Arun K. Rishi, Ramzi M. Mohammad, Adhip P.N. Majumdar

Mol Cancer Ther (2010) 9 (6): 1503–1514.

https://doi.org/10.1158/1535-7163.MCT-10-0019

Published: 09 June 2010

View article titled, ErbB-Inhibitory Protein: A Modified Ectodomain of Epidermal Growth Factor Receptor Synergizes with Dasatinib to Inhibit Growth of Breast Cancer Cells

Includes: Supplementary data

Journal Articles

Inactivation of NF-κB by 3,3′-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells

KM Wahidur Rahman, Shadan Ali, Amro Aboukameel, Sanila H. Sarkar, Zhiwei Wang, Philip A. Philip, Wael A. Sakr, Avraham Raz

Mol Cancer Ther (2007) 6 (10): 2757–2765.

https://doi.org/10.1158/1535-7163.MCT-07-0336

Published: 15 October 2007

View article titled, Inactivation of NF-κB by 3,3′-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells

Journal Articles

Transactivator of transcription–tagged cell cycle and apoptosis regulatory protein-1 peptides suppress the growth of human breast cancer cells in vitro and in vivo

Liyue Zhang, Edi Levi, Pralay Majumder, Yingjie Yu, Amro Aboukameel, Jianhua Du, Hu Xu, Ramzi Mohammad, James S. Hatfield, Anil Wali, Volkan Adsay, Adhip P.N. Majumdar, Arun K. Rishi

Mol Cancer Ther (2007) 6 (5): 1661–1672.

https://doi.org/10.1158/1535-7163.MCT-06-0653

Published: 18 May 2007

View article titled, Transactivator of transcription–tagged cell cycle and apoptosis regulatory protein-1 peptides suppress the growth of human breast cancer cells in vitro and in vivo

Journal Articles

Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X_L [(−)-gossypol] against diffuse large cell lymphoma

Ramzi M. Mohammad, Shaomeng Wang, Amro Aboukameel, Ben Chen, Xihan Wu, Jianyong Chen, Ayad Al-Katib

Mol Cancer Ther (2005) 4 (1): 13–21.

https://doi.org/10.1158/1535-7163.13.4.1

Published: 18 January 2005

View article titled, Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-XL [(−)-gossypol] against diffuse large cell lymphoma

Journal Articles

Genistein sensitizes diffuse large cell lymphoma to CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy

Ramzi M. Mohammad, Ayad Al-Katib, Amro Aboukameel, Daniel R. Doerge, Fazlul Sarkar, Omer Kucuk

Mol Cancer Ther (2003) 2 (12): 1361–1368.

Published: 05 January 2004

View article titled, Genistein sensitizes diffuse large cell lymphoma to CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy

NARROW

Anticancer Efficacy of KRAS^G12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRAS^G12C-Mutant Pancreatic and Lung Cancers

PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus

Novel p21-Activated Kinase 4 (PAK4) Allosteric Modulators Overcome Drug Resistance and Stemness in Pancreatic Ductal Adenocarcinoma

A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo

Garcinol Regulates EMT and Wnt Signaling Pathways In Vitro and In Vivo, Leading to Anticancer Activity against Breast Cancer Cells

Adamantyl-Substituted Retinoid-Related Molecules Induce Apoptosis in Human Acute Myelogenous Leukemia Cells

ErbB-Inhibitory Protein: A Modified Ectodomain of Epidermal Growth Factor Receptor Synergizes with Dasatinib to Inhibit Growth of Breast Cancer Cells

Inactivation of NF-κB by 3,3′-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells

Transactivator of transcription–tagged cell cycle and apoptosis regulatory protein-1 peptides suppress the growth of human breast cancer cells in vitro and in vivo

Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-X_L [(−)-gossypol] against diffuse large cell lymphoma

Genistein sensitizes diffuse large cell lymphoma to CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy

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