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Amrita V. Kamath
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Journal Articles

Valency of HER2 Targeting Antibodies Influences Tumor Cell Internalization and Penetration

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Madeleine K. Ramos, Danielle Mandikian, Lauren N. Sermeño, Anna King, Alecia T. Dent, Jason Ho, Sheila Ulufatu, T. Noelle Lombana, Christoph Spiess, Mary Ann T. Go, Shang-Fan Yu, Amrita V. Kamath, Gregory Z. Ferl, C. Andrew Boswell
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (10): 1956–1965.
https://doi.org/10.1158/1535-7163.MCT-20-1097
Published: 01 October 2021
View article titled, Valency of HER2 Targeting Antibodies Influences Tumor Cell Internalization and Penetration
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Includes: Supplementary data
Journal Articles

Imaging Reveals Importance of Shape and Flexibility for Glomerular Filtration of Biologics

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Hanine Rafidi, Alberto Estevez, Gregory Z. Ferl, Danielle Mandikian, Shannon Stainton, Lauren Sermeño, Simon P. Williams, Amrita V. Kamath, James T. Koerber, C. Andrew Boswell
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (10): 2008–2015.
https://doi.org/10.1158/1535-7163.MCT-21-0116
Published: 01 October 2021
View article titled, Imaging Reveals Importance of Shape and Flexibility for Glomerular Filtration of Biologics
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Includes: Supplementary data
Journal Articles

Calicheamicin Antibody–Drug Conjugates with Improved Properties

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Breanna S. Vollmar, Chris Frantz, Melissa M. Schutten, Fiona Zhong, Geoffrey del Rosario, Mary Ann T. Go, Shang-Fan Yu, Douglas D. Leipold, Amrita V. Kamath, Carl Ng, Keyang Xu, Josefa dela Cruz-Chuh, Katherine R. Kozak, Jinhua Chen, Zijin Xu, John Wai, Pragya Adhikari, Hans K. Erickson, Peter S. Dragovich, Andrew G. Polson, Thomas H. Pillow
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2021) 20 (6): 1112–1120.
https://doi.org/10.1158/1535-7163.MCT-20-0035
Published: 01 June 2021
View article titled, Calicheamicin Antibody–Drug Conjugates with Improved Properties
Open the PDF for Calicheamicin Antibody–Drug Conjugates with Improved Properties in another window
Includes: Supplementary data
Journal Articles

Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody–Drug Conjugates with Self-Immolative Disulfide Linkers

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Thomas H. Pillow, Melissa Schutten, Shang-Fan Yu, Rachana Ohri, Jack Sadowsky, Kirsten Achilles Poon, Willy Solis, Fiona Zhong, Geoffrey Del Rosario, Mary Ann T. Go, Jeffrey Lau, Sharon Yee, Jintang He, Luna Liu, Carl Ng, Keyang Xu, Douglas D. Leipold, Amrita V. Kamath, Donglu Zhang, Luke Masterson, Stephen J. Gregson, Philip W. Howard, Fan Fang, Jinhua Chen, Janet Gunzner-Toste, Katherine K. Kozak, Susan Spencer, Paul Polakis, Andrew G. Polson, John A. Flygare, Jagath R. Junutula
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2017) 16 (5): 871–878.
https://doi.org/10.1158/1535-7163.MCT-16-0641
Published: 02 May 2017
View article titled, Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody–Drug Conjugates with Self-Immolative Disulfide Linkers
Open the PDF for Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody–Drug Conjugates with Self-Immolative Disulfide Linkers in another window
Includes: Supplementary data