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Journal Articles

Targeting CD73 with AB680 (Quemliclustat), a novel and potent small molecule CD73 inhibitor, restores immune functionality and facilitates anti-tumor immunity

Dana Piovesan, Joanne BL. Tan, Annette Becker, Jesus Banuelos, Nell Narasappa, Daniel DiRenzo, Kristen Zhang, Ada Chen, Elaine Ginn, Akshata R. Udyavar, Fangfang Yin, Susan L. Paprcka, Bhamini Purandare, Timothy W. Park, Nikki Kimura, Jaroslaw Kalisiak, Stephen W. Young, Jay P. Powers, Uli Schindler, Kelsey E. Sivick, Matthew J. Walters
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther molcanther.0802.2021.
DOI: https://doi.org/10.1158/1535-7163.MCT-21-0802
Published: 11 April 2022
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Includes: Supplementary data
Journal Articles

Abstract C050: A novel, potent, and selective hypoxia-inducible factor (HIF)-2α antagonist

Kelsey E Sivick Gauthier, Kenneth V Lawson, Dana Piovesan, Matthew J Walters, Ada Chen, Xiaoning Zhao, Cesar Meleza, Nikki Kimura, Tim Park, Steve Young, Anh Tran, Samuel L Drew, Lixia Jin, Manmohan Leleti, Elaine Ginn, Jay P Powers
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2019) 18 (12_Supplement): C050.
DOI: https://doi.org/10.1158/1535-7163.TARG-19-C050
Published: 01 December 2019
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Journal Articles

The MDM2 Inhibitor AMG 232 Demonstrates Robust Antitumor Efficacy and Potentiates the Activity of p53-Inducing Cytotoxic Agents

Jude Canon, Tao Osgood, Steven H. Olson, Anne Y. Saiki, Rebecca Robertson, Dongyin Yu, John Eksterowicz, Qiuping Ye, Lixia Jin, Ada Chen, Jing Zhou, David Cordover, Stephen Kaufman, Richard Kendall, Jonathan D. Oliner, Angela Coxon, Robert Radinsky
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2015) 14 (3): 649–658.
DOI: https://doi.org/10.1158/1535-7163.MCT-14-0710
Published: 09 March 2015
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Includes: Supplementary data
Journal Articles

Preclinical Evaluation of AMG 925, a FLT3/CDK4 Dual Kinase Inhibitor for Treating Acute Myeloid Leukemia

Kathleen Keegan, Cong Li, Zhihong Li, Ji Ma, Mark Ragains, Suzanne Coberly, David Hollenback, John Eksterowicz, Lingming Liang, Margaret Weidner, Justin Huard, Xianghong Wang, Grace Alba, Jessica Orf, Mei-Chu Lo, Sharon Zhao, Rachel Ngo, Ada Chen, Lily Liu, Timothy Carlson, Christophe Quéva, Lawrence R. McGee, Julio Medina, Alexander Kamb, Dineli Wickramasinghe, Kang Dai
Journal: Molecular Cancer Therapeutics
Series: Author Choice
Mol Cancer Ther (2014) 13 (4): 880–889.
DOI: https://doi.org/10.1158/1535-7163.MCT-13-0858
Published: 06 April 2014
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Includes: Supplementary data
Journal Articles

Abstract A279: Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor.

Kang Dai, Kathleen Keegan, Zhihong Li, Ma Ji, Cong Li, John Eksterowicz, Coberly Suzanne, David Hollenback, Margret Weidner, Justin Huard, Lingming Liang, Grace Alba, Jessica Orf, Mei-Chu Lo, Sharon Zhao, Rachel Ngo, Ada Chen, Lily Liu, Timothy Carlson, Lawrence R. McGee, Julio Medina, Alexander Kamb, Dineli Wickramasinghe
Journal: Molecular Cancer Therapeutics
Mol Cancer Ther (2013) 12 (11_Supplement): A279.
DOI: https://doi.org/10.1158/1535-7163.TARG-13-A279
Published: 01 November 2013
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