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1 June 2007
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A heat map of genes associated with EMT shows differential expression according to gefitinib response in a panel of HNSCC and NSCLC cell lines. HNSCC lines are listed in light pink or light blue boxes and NSCLC lines are shown in pink or blue boxes. Genes in blue are down-regulated and genes in red are up-regulated. For details, see Frederick et al. in this issue. - PDF Icon PDF LinkTable of Contents
ISSN 1535-7163
EISSN 1538-8514
Issue Sections
Research Articles: Therapeutics, Targets, and Development
5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells
Tanyel Kiziltepe; Teru Hideshima; Laurence Catley; Noopur Raje; Hiroshi Yasui; Norihiko Shiraishi; Yutaka Okawa; Hiroshi Ikeda; Sonia Vallet; Samantha Pozzi; Kenji Ishitsuka; Enrique M. Ocio; Dharminder Chauhan; Kenneth C. Anderson
Suppression of pancreatic tumor growth by combination chemotherapy with sulindac and LC-1 is associated with cyclin D1 inhibition in vivo
Michele T. Yip-Schneider; Huangbing Wu; Matthew Ralstin; Constantin Yiannoutsos; Peter A. Crooks; Sundar Neelakantan; Stephen Noble; Harikrishna Nakshatri; Christopher J. Sweeney; C. Max Schmidt
The peroxisome proliferator-activated receptor-γ agonist troglitazone inhibits transforming growth factor-β–mediated glioma cell migration and brain invasion
Roland Coras; Annett Hölsken; Sebastian Seufert; Jan Hauke; Ilker Y. Eyüpoglu; Martin Reichel; Christian Tränkle; Florian A. Siebzehnrübl; Rolf Buslei; Ingmar Blümcke; Eric Hahnen
Wnt3/RhoA/ROCK signaling pathway is involved in adhesion-mediated drug resistance of multiple myeloma in an autocrine mechanism
Masayoshi Kobune; Hiroki Chiba; Junji Kato; Kazunori Kato; Kiminori Nakamura; Yutaka Kawano; Kohichi Takada; Rishu Takimoto; Tetsuji Takayama; Hirofumi Hamada; Yoshiro Niitsu
Antitumor activity of CTFB, a novel anticancer agent, is associated with the down-regulation of nuclear factor-κB expression and proteasome activation in head and neck squamous carcinoma cell lines
Sergej Skvortsov; Ira Skvortsova; Taras Stasyk; Natalia Schiefermeier; Andreas Neher; Andreas R. Gunkel; Guenther K. Bonn; Lukas A. Huber; Peter Lukas; Christopher M. Pleiman; Heinz Zwierzina
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