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Issues

Volume 4, Issue 8
1 August 2005
Molecular Cancer Therapeutics Cover Image for Volume 4, Issue 8
All Issues
ISSN 1535-7163
EISSN 1538-8514
Issue Sections

ARTICLE

Murine double minute 2 as a therapeutic target for radiation sensitization of lung cancer
Carolyn Cao; Eric T. Shinohara; Kenneth J. Niermann; Edwin F. Donnelly; Xinping Chen; Dennis E. Hallahan; Bo Lu
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Integrin-linked kinase is a potential therapeutic target for anaplastic thyroid cancer
Maher N. Younes; Seungwon Kim; Orhan G. Yigitbasi; Mahitosh Mandal; Samar A. Jasser; Yasemin Dakak Yazici; Bradley A. Schiff; Adel El-Naggar; Benjamin N. Bekele; Gordon B. Mills; Jeffrey N. Myers
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Competitive disruption of the tumor-promoting function of membrane type 1 matrix metalloproteinase/matrix metalloproteinase-14 in vivo
Takahiro Nonaka; Kunika Nishibashi; Yoshifumi Itoh; Ikuo Yana; Motoharu Seiki
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T315I-mutated Bcr-Abl in chronic myeloid leukemia and imatinib: insights from a computational study
Sabrina Pricl; Maurizio Fermeglia; Marco Ferrone; Elena Tamborini
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Hedamycin, a DNA alkylator, induces γH2AX and chromosome aberrations: Involvement of phosphatidylinositol 3-kinase–related kinases and DNA replication fork movement
Lan Chun Tu; Sei ichi Matsui; Terry A. Beerman
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Temporal quantitation of mutant Kit tyrosine kinase signaling attenuated by a novel thiophene kinase inhibitor OSI-930
Filippo Petti; April Thelemann; Jen Kahler; Siobhan McCormack; Linda Castaldo; Tony Hunt; Lydia Nuwaysir; Lynn Zeiske; Herbert Haack; Laura Sullivan; Andrew Garton; John D. Haley
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Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis
Michael R. D'Andrea; Jay M. Mei; Robert W. Tuman; Robert A. Galemmo; Dana L. Johnson
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The immunocytokine scFv23/TNF sensitizes HER-2/neu–overexpressing SKBR-3 cells to tumor necrosis factor (TNF) via up-regulation of TNF receptor-1
Mi-Ae Lyu; Michael G. Rosenblum
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Inhibition of insulin-like growth factor-I receptor (IGF-IR) signaling and tumor cell growth by a fully human neutralizing anti–IGF-IR antibody
Yan Wang; Judith Hailey; Denise Williams; Yaolin Wang; Philip Lipari; Michael Malkowski; Xiaoying Wang; Lei Xie; Guanghua Li; Deba Saha; Wai Lam W. Ling; Susan Cannon-Carlson; Robert Greenberg; Robert A. Ramos; Robert Shields; Leonard Presta; Peter Brams; W. Robert Bishop; Jonathan A. Pachter
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Histone deacetylase inhibitors induced caspase-independent apoptosis in human pancreatic adenocarcinoma cell lines
Pilar García-Morales; Angeles Gómez-Martínez; Alfredo Carrato; Isabel Martínez-Lacaci; Víctor M. Barberá; José L. Soto; Estefanía Carrasco-García; María P. Menéndez-Gutierrez; María D. Castro-Galache; José A. Ferragut; Miguel Saceda
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Cell cycle checkpoint signaling involved in histone deacetylase inhibition and radiation-induced cell death
Ragnhild V. Nome; Åse Bratland; Gunhild Harman; Øystein Fodstad; Yvonne Andersson; Anne Hansen Ree
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Selenium disrupts estrogen receptor α signaling and potentiates tamoxifen antagonism in endometrial cancer cells and tamoxifen-resistant breast cancer cells
Yatrik M. Shah; Mariam Al-Dhaheri; Yan Dong; Clement Ip; Frank E. Jones; Brian G. Rowan
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Mitochondria are the primary target in isothiocyanate-induced apoptosis in human bladder cancer cells
Li Tang; Yuesheng Zhang
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The antiproliferative agent MLN944 preferentially inhibits transcription
Sarah A. Byers; Blanca Schafer; Darshan S. Sappal; Jeffery Brown; David H. Price
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Increased expression of the large subunit of ribonucleotide reductase is involved in resistance to gemcitabine in human mammary adenocarcinoma cells
Lars Petter Jordheim; Olivier Guittet; Michel Lepoivre; Carlos M. Galmarini; Charles Dumontet
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Pristimerin induces caspase-dependent apoptosis in MDA-MB-231 cells via direct effects on mitochondria
Chin-Chung Wu; Mei-Ling Chan; Wen-Ying Chen; Ching-Yi Tsai; Fang-Rong Chang; Yang-Chang Wu
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NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale—within the United States—of Bavencio® (avelumab), a pharmaceutical owned by Merck.  None of these funds are being, or will be, used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.

  • Online ISSN 1538-8514
  • Print ISSN 1535-7163

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