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Issues

Volume 4, Issue 10
1 October 2005
Issue Cover
All Issues
ISSN 1535-7163
EISSN 1538-8514
Issue Sections

ARTICLE

A role for PKCζ in potentiation of the topoisomerase II activity and etoposide cytotoxicity by wortmannin
Caroline Reis; Nicole Giocanti; Christophe Hennequin; Frédérique Mégnin-Chanet; Marie Fernet; Rodolphe Filomenko; Ali Bettaieb; Eric Solary; Vincent Favaudon
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Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1α and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells
Qunzhou Zhang; Xudong Tang; Qing Yi Lu; Zuo Feng Zhang; Jimmy Brown; Anh D. Le
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Sulindac sulfide–induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2
Frank A. Sinicrope; Robert C. Penington
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Down-regulation of DNA mismatch repair proteins in human and murine tumor spheroids: implications for multicellular resistance to alkylating agents
Giulio Francia; Shane K. Green; Guido Bocci; Shan Man; Urban Emmenegger; John M.L. Ebos; Adina Weinerman; Yuval Shaked; Robert S. Kerbel
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Docetaxel induces cell death through mitotic catastrophe in human breast cancer cells
David L. Morse; Heather Gray; Claire M. Payne; Robert J. Gillies
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Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer
Curtis Balch; Pearlly Yan; Teresa Craft; Suzanne Young; David G. Skalnik; Tim H-M. Huang; Kenneth P. Nephew
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Supplementary data
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Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2′-deoxycytidine
Jody C. Chuang; Christine B. Yoo; Jennifer M. Kwan; Tony W.H. Li; Gangning Liang; Allen S. Yang; Peter A. Jones
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Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity
Lindsay Stimson; Martin G. Rowlands; Yvette M. Newbatt; Nicola F. Smith; Florence I. Raynaud; Paul Rogers; Vassilios Bavetsias; Stephen Gorsuch; Michael Jarman; Andrew Bannister; Tony Kouzarides; Edward McDonald; Paul Workman; G. Wynne Aherne
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Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade
Yijiang Shi; Huajun Yan; Patrick Frost; Joseph Gera; Alan Lichtenstein
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Radiosensitization of MDA-MB-231 breast tumor cells by adenovirus-mediated overexpression of a fragment of the XRCC4 protein
Kara R. Jones; David A. Gewirtz; Steven M. Yannone; Shaoming Zhou; David G. Schatz; Kristoffer Valerie; Lawrence F. Povirk
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Counteracting tumor radioresistance by targeting DNA repair
Dörthe Schaue; William H. McBride
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Suppression of tumor cell invasion by cyclooxygenase inhibitors is mediated by thrombospondin-1 via the early growth response gene Egr-1
Yuseok Moon; Frank G. Bottone, Jr.; Michael F. McEntee; Thomas E. Eling
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Drugs aimed at targeting characteristic karyotypic phenotypes of cancer cells
Anders Wallqvist; Ruili Huang; David G. Covell; Anna V. Roschke; Kristen S. Gelhaus; Ilan R. Kirsch
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Supplementary data
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The anticancer activity of the fungal metabolite terrecyclic acid A is associated with modulation of multiple cellular stress response pathways
Thomas J. Turbyville; E.M. Kithsiri Wijeratne; Luke Whitesell; A.A. Leslie Gunatilaka
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Knockdown of c-Met by adenovirus-delivered small interfering RNA inhibits hepatocellular carcinoma growth in vitro and in vivo
Sheng-Zhou Zhang; Fei-Yan Pan; Jian-Feng Xu; Jun Yuan; Shi-Ying Guo; Gu Dai; Bin Xue; Wei-Gan Shen; Chuan-Jun Wen; Dong-Hong Zhao; Chao-Jun Li
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Role of p21waf1/cip1 in effects of oxaliplatin in colorectal cancer cells
Taishi Hata; Hirofumi Yamamoto; Chew Yee Ngan; Minoru Koi; Akimitsu Takagi; Bazarragchaa Damdinsuren; Masayoshi Yasui; Yujiro Fujie; Takeshi Matsuzaki; Hiromichi Hemmi; Xundi Xu; Kotaro Kitani; Yosuke Seki; Ichiro Takemasa; Masataka Ikeda; Mitsugu Sekimoto; Nariaki Matsuura; Morito Monden
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Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells
Roohangiz Safaei; Barrett J. Larson; Timothy C. Cheng; Michael A. Gibson; Shinji Otani; Wiltrud Naerdemann; Stephen B. Howell
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Genome-wide transcriptional analysis of carboplatin response in chemosensitive and chemoresistant ovarian cancer cells
David Peters; John Freund; Robert L. Ochs
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WMC-79, a potent agent against colon cancers, induces apoptosis through a p53-dependent pathway
Teresa Kosakowska-Cholody; W. Marek Cholody; Anne Monks; Barbara A. Woynarowska; Christopher J. Michejda
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YC-1 suppresses constitutive nuclear factor-κB activation and induces apoptosis in human prostate cancer cells
Yao-Ting Huang; Shiow-Lin Pan; Jih-Hwa Guh; Ya-Ling Chang; Fang-Yu Lee; Sheng-Chu Kuo; Che-Ming Teng
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Minireview

Using bioinformatics and genome analysis for new therapeutic interventions
David W. Mount; Ritu Pandey
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