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Issues

Volume 4, Issue 1
1 January 2005
Molecular Cancer Therapeutics Cover Image for Volume 4, Issue 1
All Issues
ISSN 1535-7163
EISSN 1538-8514
Issue Sections

ARTICLE

Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma
Risa Torkin; Jean-François Lavoie; David R. Kaplan; Herman Yeger
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Preclinical studies of a nonpeptidic small-molecule inhibitor of Bcl-2 and Bcl-XL [(−)-gossypol] against diffuse large cell lymphoma
Ramzi M. Mohammad; Shaomeng Wang; Amro Aboukameel; Ben Chen; Xihan Wu; Jianyong Chen; Ayad Al-Katib
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(−)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-XL-mediated apoptosis resistance
Christopher L. Oliver; Michelle B. Miranda; Sanjeev Shangary; Stephanie Land; Shaomeng Wang; Daniel E. Johnson
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The nuclear factor κB inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)–induced apoptosis in antiestrogen-resistant breast cancer cells
Rebecca B. Riggins; Alan Zwart; Ruchi Nehra; Robert Clarke
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Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by α-tocopheryl succinate in human prostate cancer cells
Ke Zu; Lesleyann Hawthorn; Clement Ip
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Selective inhibitors of MEK1/ERK44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells
Yunjie Sun; Frank A. Sinicrope
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Epigenetic regulation of O6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins
Rebecca P. Danam; Sherie R. Howell; Thomas P. Brent; Linda C. Harris
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Covalent binding of antitumor benzoacronycines to double-stranded DNA induces helix opening and the formation of single-stranded DNA: Unique consequences of a novel DNA-bonding mechanism
Marie-Hélène David-Cordonnier; William Laine; Amélie Lansiaux; Frédéric Rosu; Pierre Colson; Edwin de Pauw; Sylvie Michel; Francois Tillequin; Michel Koch; John A. Hickman; Alain Pierré; Christian Bailly
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Epigallocatechin-3-gallate induces apoptosis in estrogen receptor–negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation
Anshu M. Roy; Manjeshwar S. Baliga; Santosh K. Katiyar
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Anti-α4 integrin monoclonal antibody inhibits multiple myeloma growth in a murine model
Dian L. Olson; Linda C. Burkly; Diane R. Leone; Brian M. Dolinski; Roy R. Lobb
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Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition
Ranjit K. Goudar; Qing Shi; Mark D. Hjelmeland; Stephen T. Keir; Roger E. McLendon; Carol J. Wikstrand; Elizabeth D. Reese; Charles A. Conrad; Peter Traxler; Heidi A. Lane; David A. Reardon; Webster K. Cavenee; Xiao-Fan Wang; Darell D. Bigner; Henry S. Friedman; Jeremy N. Rich
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Roscovitine-induced up-regulation of p53AIP1 protein precedes the onset of apoptosis in human MCF-7 breast cancer cells
Józefa Węsierska-Gądek; Marieta Gueorguieva; Marcel Horky
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Metabolism and pharmacokinetics of the cyclin-dependent kinase inhibitor R-roscovitine in the mouse
Bernard P. Nutley; Florence I. Raynaud; Stuart C. Wilson; Peter M. Fischer; Angela Hayes; Phyllis M. Goddard; Steven J. McClue; Michael Jarman; David P. Lane; Paul Workman
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Role of phorbol ester localization in determining protein kinase C or RasGRP3 translocation: Real-time analysis using fluorescent ligands and proteins
Derek C. Braun; Yeyu Cao; Shaomeng Wang; Susan H. Garfield; Gang Min Hur; Peter M. Blumberg
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Distinct gene expression patterns in a tamoxifen-sensitive human mammary carcinoma xenograft and its tamoxifen-resistant subline MaCa 3366/TAM
Michael Becker; Anette Sommer; Jörn R. Krätzschmar; Henrik Seidel; Hans-Dieter Pohlenz; Iduna Fichtner
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A therapeutic model for advanced endometrial cancer: Systemic progestin in combination with local adenoviral-mediated progesterone receptor expression
Donghai Dai; Lina Albitar; Tan Nguyen; Laura L. Laidler; Meenakshi Singh; Kimberly K. Leslie
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Carotenoids activate the antioxidant response element transcription system
Anat Ben-Dor; Michael Steiner; Larisa Gheber; Michael Danilenko; Noga Dubi; Karin Linnewiel; Anat Zick; Yoav Sharoni; Joseph Levy
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NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale—within the United States—of Bavencio® (avelumab), a pharmaceutical owned by Merck.  None of these funds are being, or will be, used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.

  • Online ISSN 1538-8514
  • Print ISSN 1535-7163

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