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Issues

Volume 3, Issue 9
1 September 2004
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ISSN 1535-7163
EISSN 1538-8514
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ARTICLE

ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor with additional activity against epidermal growth factor receptor tyrosine kinase, inhibits orthotopic growth and angiogenesis of gastric cancer
Marya F. McCarty; Jane Wey; Oliver Stoeltzing; Wenbiao Liu; Fan Fan; Corazon Bucana; Paul F. Mansfield; Anderson J. Ryan; Lee M. Ellis
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Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease
Sukhdev S. Brar; Claude Grigg; Kimberly S. Wilson; Walter D. Holder, Jr.; Didier Dreau; Catherine Austin; Mareva Foster; Andrew J. Ghio; A. Richard Whorton; Grayson W. Stowell; Linda B. Whittall; Robert R. Whittle; David P. White; Thomas P. Kennedy
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Biological evaluation of cryptophycin 52 fragment A analogues: Effect of the multidrug resistance ATP binding cassette transporters on antitumor activity
Rima S. Al-awar; Thomas H. Corbett; James E. Ray; Lisa Polin; Joseph H. Kennedy; Margaret M. Wagner; Daniel C. Williams
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Structure-based design of a selective heparanase inhibitor as an antimetastatic agent
Keisuke Ishida; Go Hirai; Koji Murakami; Takayuki Teruya; Siro Simizu; Mikiko Sodeoka; Hiroyuki Osada
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In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities
Salvatore DeBonis; Dimitrios A. Skoufias; Luc Lebeau; Roman Lopez; Gautier Robin; Robert L. Margolis; Richard H. Wade; Frank Kozielski
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Gene expression changes induced by green tea polyphenol (−)-epigallocatechin-3-gallate in human bronchial epithelial 21BES cells analyzed by DNA microarray
Ragini Vittal; Zachariah E. Selvanayagam; Yi Sun; Jungil Hong; Fang Liu; Khew-Voon Chin; Chung S. Yang
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Effect of curcumin on normal and tumor cells: Role of glutathione and bcl-2
Christine Syng-ai; A. Leela Kumari; Ashok Khar
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Differential sensitivity of cancer cells to docosahexaenoic acid–induced cytotoxicity: The potential importance of down-regulation of superoxide dismutase 1 expression
Wei-Qun Ding; Joshua L. Vaught; Hanako Yamauchi; Stuart E. Lind
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Gefitinib reverses breast cancer resistance protein–mediated drug resistance
Kae Yanase; Satomi Tsukahara; Sakiyo Asada; Etsuko Ishikawa; Yasuo Imai; Yoshikazu Sugimoto
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Brain tumor cell lines resistant to O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations
Manny D. Bacolod; Stewart P. Johnson; Anthony E. Pegg; M. Eileen Dolan; Robert C. Moschel; Nancy S. Bullock; Qingming Fang; O. Michael Colvin; Paul Modrich; Darell D. Bigner; Henry S. Friedman
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Neuronal-associated microtubule proteins class III β-tubulin and MAP2c in neuroblastoma: Role in resistance to microtubule-targeted drugs
Sima Don; Nicole M. Verrills; Tracy Y.E. Liaw; Marjorie L.M. Liu; Murray D. Norris; Michelle Haber; Maria Kavallaris
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CHK1 and CHK2 are differentially involved in mismatch repair–mediated 6-thioguanine-induced cell cycle checkpoint responses
Tao Yan; Anand B. Desai; James W. Jacobberger; R. Michael Sramkoski; Tamalette Loh; Timothy J. Kinsella
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Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: Modulation of apoptosis, proliferation, and fractal dimension
Hemant K. Roy; Patrick Iversen; John Hart; Yang Liu; Jennifer L. Koetsier; Young Kim; Dhanajay P. Kunte; Madhavi Madugula; Vadim Backman; Ramesh K. Wali
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Chemoinducible gene therapy: A strategy to enhance doxorubicin antitumor activity
Carlos A. Lopez; Eric T. Kimchi; Helena J. Mauceri; James O. Park; Neil Mehta; Kevin T. Murphy; Michael A. Beckett; Samuel Hellman; Mitchell C. Posner; Donald W. Kufe; Ralph R. Weichselbaum
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Muscle-targeted interleukin-12 gene therapy of orthotopic hepatocellular carcinoma in mice using in vivo electrosonoporation
Yo-ichi Yamashita; Mitsuo Shimada; Ryosuke Minagawa; Eiji Tsujita; Norifumi Harimoto; Shinji Tanaka; Ken Shirabe; Jun-ichi Miyazaki; Yoshihiko Maehara
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