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Volume 3, Issue 7
1 July 2004
Molecular Cancer Therapeutics Cover Image for Volume 3, Issue 7
All Issues
ISSN 1535-7163
EISSN 1538-8514
Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling
Nathan T. Ihle; Ryan Williams; Sherry Chow; Wade Chew; Margareta I. Berggren; Gillian Paine-Murrieta; Daniel J. Minion; Robert J. Halter; Peter Wipf; Robert Abraham; Lynn Kirkpatrick; Garth Powis
View articletitled, Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling
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Down-regulation of protein kinase Cη potentiates the cytotoxic effects of exogenous tumor necrosis factor–related apoptosis-inducing ligand in PC-3 prostate cancer cells
Jürgen Sonnemann; Volker Gekeler; Antje Sagrauske; Cornelia Müller; Hans-Peter Hofmann; James F. Beck
View articletitled, Down-regulation of protein kinase Cη potentiates the cytotoxic effects of exogenous tumor necrosis factor–related apoptosis-inducing ligand in PC-3 prostate cancer cells
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Lack of neurotoxicity of the vascular targeting agent ZD6126 following repeated i.v. dosing in the rat
Steve A. Horner; Sarah Gould; James P. Noakes; Niccola J. Rattray; Sandra L. Allen; Elena Zotova; Joseph C. Arezzo
View articletitled, Lack of neurotoxicity of the vascular targeting agent ZD6126 following repeated i.v. dosing in the rat
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A hybrid fibronectin motif protein as an integrin targeting selective tumor vascular thrombogen
Cheng Liu; Craig Dickinson; Justin Shobe; Fernando Doñate; Wolfram Ruf; Thomas Edgington
View articletitled, A hybrid fibronectin motif protein as an integrin targeting selective tumor vascular thrombogen
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Curcumin sensitizes prostate cancer cells to tumor necrosis factor–related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-κB through suppression of IκBα phosphorylation
Dorrah Deeb; Hao Jiang; Xiaohua Gao; Mikehl S. Hafner; Henry Wong; George Divine; Robert A. Chapman; Scott A. Dulchavsky; Subhash C. Gautam
View articletitled, Curcumin sensitizes prostate cancer cells to tumor necrosis factor–related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-κB through suppression of IκBα phosphorylation
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Polyamine catabolism in platinum drug action: Interactions between oxaliplatin and the polyamine analogue N1,N11-diethylnorspermine at the level of spermidine/spermine N1-acetyltransferase
Suzanne Hector; Carl W. Porter; Debora L. Kramer; Kimberly Clark; Joshua Prey; Nicholas Kisiel; Paula Diegelman; Ying Chen; Lakshmi Pendyala
View articletitled, Polyamine catabolism in platinum drug action: Interactions between oxaliplatin and the polyamine analogue <em>N</em><sup>1</sup>,<em>N</em><sup>11</sup>-diethylnorspermine at the level of spermidine/spermine <em>N</em><sup>1</sup>-acetyltransferase
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Role of the transcription factor Ets-1 in cisplatin resistance
Leigh A. Wilson; Hirotaka Yamamoto; Gurmit Singh
View articletitled, Role of the transcription factor Ets-1 in cisplatin resistance
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Inhibition of ABCB1 (MDR1) and ABCB4 (MDR3) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells
Zhenfeng Duan; Katherine A. Brakora; Michael V. Seiden
View articletitled, Inhibition of <em>ABCB1</em> (<em>MDR1</em>) and <em>ABCB4</em> (<em>MDR3</em>) expression by small interfering RNA and reversal of paclitaxel resistance in human ovarian cancer cells
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Activation of protein kinase C βII/ε-c-Jun NH2-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin
Yoshiki Miyata; Takashi Sato; Masamichi Yano; Akira Ito
View articletitled, Activation of protein kinase C βII/ε-c-Jun NH<sub>2</sub>-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin
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In vitro evaluation of dimethane sulfonate analogues with potential alkylating activity and selective renal cell carcinoma cytotoxicity
Susan D. Mertins; Timothy G. Myers; Susan L. Holbeck; Wilma Medina-Perez; Elaine Wang; Glenda Kohlhagen; Yves Pommier; Susan E. Bates
View articletitled, <em>In vitro</em> evaluation of dimethane sulfonate analogues with potential alkylating activity and selective renal cell carcinoma cytotoxicity
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Transcriptional signature of flavopiridol-induced tumor cell death
Xing Lü; William E. Burgan; Michael A. Cerra; Eric Y. Chuang; Mong-Hsun Tsai; Philip J. Tofilon; Kevin Camphausen
View articletitled, Transcriptional signature of flavopiridol-induced tumor cell death
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Gene profiling and the cyclin-dependent kinase inhibitor flavopiridol: What's in a name?
Steven Grant; Paul Dent
View articletitled, Gene profiling and the cyclin-dependent kinase inhibitor flavopiridol: What's in a name?
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A strategy for cancer prevention: Stimulation of the Nrf2-ARE signaling pathway
Yuesheng Zhang; Gary B. Gordon
View articletitled, A strategy for cancer prevention: Stimulation of the Nrf2-ARE signaling pathway
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Articles

Selenite-induced p53 Ser-15 phosphorylation and caspase-mediated apoptosis in LNCaP human prostate cancer cells
Cheng Jiang; Hongbo Hu; Barbara Malewicz; Zaisen Wang; Junxuan Lü
View articletitled, Selenite-induced p53 Ser-15 phosphorylation and caspase-mediated apoptosis in LNCaP human prostate cancer cells
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NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale—within the United States—of Bavencio® (avelumab), a pharmaceutical owned by Merck.  None of these funds are being, or will be, used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.

  • Online ISSN 1538-8514
  • Print ISSN 1535-7163

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