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Issues

Volume 3, Issue 5
1 May 2004
Molecular Cancer Therapeutics Cover Image for Volume 3, Issue 5
All Issues
ISSN 1535-7163
EISSN 1538-8514
Issue Sections

ARTICLE

Multiparametric evaluation of apoptosis: Effects of standard cytotoxic agents and the cyanoguanidine CHS 828
Henrik Lövborg; Peter Nygren; Rolf Larsson
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The insulin-like growth factor-I (IGF-I) receptor kinase inhibitor NVP-ADW742, in combination with STI571, delineates a spectrum of dependence of small cell lung cancer on IGF-I and stem cell factor signaling
G. Sakuntala Warshamana-Greene; Julie Litz; Elisabeth Buchdunger; Francesco Hofmann; Carlos Garcı́a-Echeverrı́a; Geoffrey W. Krystal
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Photodynamic therapy with indocyanine green complements and enhances low-dose cisplatin cytotoxicity in MCF-7 breast cancer cells
Elvira Crescenzi; Linda Varriale; Mariangela Iovino; Angela Chiaviello; Bianca Maria Veneziani; Giuseppe Palumbo
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Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma
Mustafa K. Ozvaran; Xiaobo X. Cao; Steven D. Miller; Brett A. Monia; Waun Ki Hong; W. Roy Smythe
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Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity
Edward G. Mimnaugh; Wanping Xu; Michele Vos; Xitong Yuan; Jennifer S. Isaacs; Kheem S. Bisht; David Gius; Len Neckers
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Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells
Dong Xiao; Candace S. Johnson; Donald L. Trump; Shivendra V. Singh
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DNA damage responses triggered by a highly cytotoxic monofunctional DNA alkylator, hedamycin, a pluramycin antitumor antibiotic
Lan Chun Tu; Thomas Melendy; Terry A. Beerman
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The novel estrogen 17α-20Z-21-[(4-amino)phenyl]-19-norpregna-1,3,5(10),20-tetraene-3,17β-diol induces apoptosis in prostate cancer cell lines at nanomolar concentrations in vitro
James A. Mobley; James O. L'Esperance; Mengchu Wu; Carolyn J. Friel; Robert H. Hanson; Shuk-Mei Ho
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Disulfide-constrained peptides that bind to the extracellular portion of the prostate-specific membrane antigen
Shawn E. Lupold; Ronald Rodriguez
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Methyl selenium metabolites decrease prostate-specific antigen expression by inducing protein degradation and suppressing androgen-stimulated transcription
Sung Dae Cho; Cheng Jiang; Barbara Malewicz; Yan Dong; Charles Y.F. Young; Kyung-Sun Kang; Yong-Soon Lee; Clement Ip; Junxuan Lü
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Different DNA lesions trigger distinct cell death responses in HCT116 colon carcinoma cells
Shaochun Bai; David W. Goodrich
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Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated–dependent and –independent mechanisms
Wai Yi Siu; Anita Lau; Talha Arooz; Jeremy P.H. Chow; Horace T.B. Ho; Randy Y.C. Poon
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Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy
Valerie Gouazé; Jing Y. Yu; Richard J. Bleicher; Tie-Yan Han; Yong-Yu Liu; Hongtao Wang; Michael M. Gottesman; Arie Bitterman; Armando E. Giuliano; Myles C. Cabot
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Identification of human polo-like kinase 1 as a potential therapeutic target in pancreatic cancer
Phillip J. Gray, Jr; David J. Bearss; Haiyong Han; Raymond Nagle; Ming-Sound Tsao; Nicholas Dean; Daniel D. Von Hoff
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Minireview

Hypoxia inducible factor-1α as a cancer drug target
Garth Powis; Lynn Kirkpatrick
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NOTICE: This notice serves to inform the reader that, in 2023, AACR received a donation by Pfizer of the rights to royalties from the sale—within the United States—of Bavencio® (avelumab), a pharmaceutical owned by Merck.  None of these funds are being, or will be, used to directly support any specific publication or author. If an individual article is published that deals with this particular drug, such article will include standard financial disclosures per AACR journal policy. For more detail regarding AACR’s established policies for authors, please go to https://aacrjournals.org/pages/editorial-policies#coi.

  • Online ISSN 1538-8514
  • Print ISSN 1535-7163

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