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Issues

Volume 3, Issue 3
1 March 2004
Issue Cover
All Issues
ISSN 1535-7163
EISSN 1538-8514
Issue Sections

ARTICLE

Nucleotide-based therapies targeting clusterin chemosensitize human lung adenocarcinoma cells both in vitro and in vivo
Laura V. July; Eliana Beraldi; Alan So; Ladan Fazli; Kenneth Evans; John C. English; Martin E. Gleave
View articletitled, Nucleotide-based therapies targeting clusterin chemosensitize human lung adenocarcinoma cells both <em>in vitro</em> and <em>in vivo</em>
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Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1α
Sarah Welsh; Ryan Williams; Lynn Kirkpatrick; Gillian Paine-Murrieta; Garth Powis
View articletitled, Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1α
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A new class of peroxisome proliferator-activated receptor γ (PPARγ) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes
Chunhua Qin; Derek Morrow; Jessica Stewart; Kyle Spencer; Weston Porter; Roger Smith, III; Timothy Phillips; Maen Abdelrahim; Ismael Samudio; Stephen Safe
View articletitled, A new class of peroxisome proliferator-activated receptor γ (PPARγ) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3′-indolyl)-1-(<em>p</em>-substituted phenyl)methanes
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Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity
James Turkson; Joon S. Kim; Shumin Zhang; Jing Yuan; Mei Huang; Matthew Glenn; Eric Haura; Said Sebti; Andrew D. Hamilton; Richard Jove
View articletitled, Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity
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Regulation of Vinca alkaloid-induced apoptosis by NF-κB/IκB pathway in human tumor cells
Yi Huang; Yong Fang; Jinmin Wu; Jennifer M. Dziadyk; Xueming Zhu; Meihua Sui; Weimin Fan
View articletitled, Regulation of <em>Vinca</em> alkaloid-induced apoptosis by NF-κB/IκB pathway in human tumor cells
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The proteasome inhibitor bortezomib synergizes with gemcitabine to block the growth of human 253JB-V bladder tumors in vivo
Ashish M. Kamat; Takashi Karashima; Darren W. Davis; Laura Lashinger; Menashe Bar-Eli; Randall Millikan; Yu Shen; Colin P. N. Dinney; David J. McConkey
View articletitled, The proteasome inhibitor bortezomib synergizes with gemcitabine to block the growth of human 253JB-V bladder tumors <em>in vivo</em>
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Antiproliferative effect of nitrosulindac (NCX 1102), a new nitric oxide-donating non-steroidal anti-inflammatory drug, on human bladder carcinoma cell lines
Sandra Huguenin; Francis Vacherot; Laurence Kheuang; Jocelyne Fleury-Feith; Marie-Claude Jaurand; Manlio Bolla; Jean-Pierre Riffaud; Dominique K. Chopin
View articletitled, Antiproliferative effect of nitrosulindac (NCX 1102), a new nitric oxide-donating non-steroidal anti-inflammatory drug, on human bladder carcinoma cell lines
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The cyclooxygenase-2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells
Tong Wu; Jing Leng; Chang Han; Anthony Jake Demetris
View articletitled, The cyclooxygenase-2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells
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Acyclic retinoid activates retinoic acid receptor β and induces transcriptional activation of p21CIP1 in HepG2 human hepatoma cells
Masumi Suzui; Masahito Shimizu; Muneyuki Masuda; Jin T. E. Lim; Naoki Yoshimi; I. Bernard Weinstein
View articletitled, Acyclic retinoid activates retinoic acid receptor β and induces transcriptional activation of p21<sup>CIP1</sup> in HepG2 human hepatoma cells
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Antitumor histone deacetylase inhibitors suppress cutaneous radiation syndrome: Implications for increasing therapeutic gain in cancer radiotherapy
Yih Lin Chung; Ae-June Wang; Lin-Fen Yao
View articletitled, Antitumor histone deacetylase inhibitors suppress cutaneous radiation syndrome: Implications for increasing therapeutic gain in cancer radiotherapy
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Down-regulation of Bcl-2 is associated with cisplatin resistance in human small cell lung cancer H69 cells
Swarajit Kumar Biswas; Jie Huang; Shalini Persaud; Alakananda Basu
View articletitled, Down-regulation of Bcl-2 is associated with cisplatin resistance in human small cell lung cancer H69 cells
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TNP-470 promotes initial vascular sprouting in xenograft tumors
Jianzhong Huang; Jason S. Frischer; Tamara New; Eugene S. Kim; Anna Serur; Alice Lee; Angela Kadenhe-Chiwishe; Daniel A. Pollyea; Akiko Yokoi; Jocelyn Holash; George D. Yancopoulos; Jessica J. Kandel; Darrell J. Yamashiro
View articletitled, TNP-470 promotes initial vascular sprouting in xenograft tumors
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Retinoic acid-induced CD38 antigen as a target for immunotoxin-mediated killing of leukemia cells
Kapil Mehta; Larry Ocanas; Fabio Malavasi; John W. Marks; Michael G. Rosenblum
View articletitled, Retinoic acid-induced CD38 antigen as a target for immunotoxin-mediated killing of leukemia cells
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Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesis
Florence I. Raynaud; Peter M. Fischer; Bernard P. Nutley; Phyllis M. Goddard; David P. Lane; Paul Workman
View articletitled, Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesis
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Commentary

Small molecule inhibition of hypoxia inducible factor-1α: A viable therapeutic approach?
Kenneth D. Tew
View articletitled, Small molecule inhibition of hypoxia inducible factor-1α: A viable therapeutic approach?
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Minireview

Cytochrome P450 enzymes: Novel options for cancer therapeutics
Morag C. E. McFadyen; William T. Melvin; Graeme I. Murray
View articletitled, Cytochrome <em>P</em>450 enzymes: Novel options for cancer therapeutics
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Calcitriol in cancer treatment: From the lab to the clinic
Tomasz M. Beer; Anne Myrthue
View articletitled, Calcitriol in cancer treatment: From the lab to the clinic
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Letters to the Editor

Correspondence re: DC Lev et al., Dacarbazine causes transcriptional up-regulation of interleukin 8 and vascular endothelial growth factor in melanoma cells: A possible escape mechanism from chemotherapy. Mol Cancer Ther, 2003;2(8):753–63.
Lucio Tentori; Grazia Graziani
View articletitled, Correspondence re: DC Lev <em>et al</em>., Dacarbazine causes transcriptional up-regulation of interleukin 8 and vascular endothelial growth factor in melanoma cells: A possible escape mechanism from chemotherapy. Mol Cancer Ther, 2003;2(8):753–63.
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