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Issues

Volume 3, Issue 12
1 December 2004
Issue Cover
All Issues
ISSN 1535-7163
EISSN 1538-8514
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ARTICLE

Antisense oligonucleotides targeted to the human α folate receptor inhibit breast cancer cell growth and sensitize the cells to doxorubicin treatment
Mona S. Jhaveri; Antonina S. Rait; Koong-Nah Chung; Jane B. Trepel; Esther H. Chang
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The small-molecule Bcl-2 inhibitor HA14-1 interacts synergistically with flavopiridol to induce mitochondrial injury and apoptosis in human myeloma cells through a free radical–dependent and Jun NH2-terminal kinase–dependent mechanism
Xin-Yan Pei; Yun Dai; Steven Grant
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Erythropoietin induces cancer cell resistance to ionizing radiation and to cisplatin
Alexandre I. Belenkov; George Shenouda; Ekatarina Rizhevskaya; Denis Cournoyer; Jean-Philippe Belzile; Luis Souhami; Slobodan Devic; Terry Y.K. Chow
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Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity
James Turkson; Shumin Zhang; Jay Palmer; Heidi Kay; Joseph Stanko; Linda B. Mora; Said Sebti; Hua Yu; Richard Jove
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Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells
Im-Sook Song; Niramol Savaraj; Zahid H. Siddik; Peiman Liu; Yingjie Wei; Chun Jing Wu; Macus Tien Kuo
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Different proteome pattern of epidermal growth factor receptor–positive colorectal cancer cell lines that are responsive and nonresponsive to C225 antibody treatment
Sergej Skvortsov; Bettina Sarg; Judith Loeffler-Ragg; Ira Skvortsova; Herbert Lindner; Helmut Werner Ott; Peter Lukas; Karl Illmensee; Heinz Zwierzina
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A humanized monoclonal antibody to carcinoembryonic antigen, labetuzumab, inhibits tumor growth and sensitizes human medullary thyroid cancer xenografts to dacarbazine chemotherapy
Rhona Stein; David M. Goldenberg
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In vitro, in vivo, and in silico analyses of the antitumor activity of 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazoles
Chee Onn Leong; Marie Suggitt; David J. Swaine; Michael C. Bibby; Malcolm F.G. Stevens; Tracey D. Bradshaw
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Modulation of breast cancer resistance protein (BCRP/ABCG2) gene expression using RNA interference
P.L. Rachel Ee; Xiaolong He; Douglas D. Ross; William T. Beck
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Characterization of a novel cell line established from a patient with Herceptin-resistant breast cancer
Minna Tanner; Anita I. Kapanen; Teemu Junttila; Olayinka Raheem; Seija Grenman; Jussi Elo; Klaus Elenius; Jorma Isola
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Doxorubicin-formaldehyde conjugates targeting αvβ3 integrin
David J. Burkhart; Brian T. Kalet; Michael P. Coleman; Glen C. Post; Tad H. Koch
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Akt up-regulation increases resistance to microtubule-directed chemotherapeutic agents through mammalian target of rapamycin
David J. VanderWeele; Rixin Zhou; Charles M. Rudin
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Epidermal growth factor receptor–related peptide inhibits growth of PC-3 prostate cancer cells
Dorota J. Marciniak; Arun K. Rishi; Fazlul H. Sarkar; Adhip P.N. Majumdar
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Highly efficient delivery of p16 antitumor peptide into aggressive leukemia/lymphoma cells using a novel transporter system
Eisaku Kondo; Masao Seto; Kazuhiro Yoshikawa; Tadashi Yoshino
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The ex vivo characterization of XR5944 (MLN944) against a panel of human clinical tumor samples
Federica Di Nicolantonio; Louise A. Knight; Pauline A. Whitehouse; Stuart J. Mercer; Sanjay Sharma; Peter A. Charlton; David Norris; Ian A. Cree
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KRN633: A selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase that suppresses tumor angiogenesis and growth
Kazuhide Nakamura; Atsushi Yamamoto; Masaru Kamishohara; Kazumi Takahashi; Eri Taguchi; Toru Miura; Kazuo Kubo; Masabumi Shibuya; Toshiyuki Isoe
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Ingenol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor–related apoptosis-inducing ligand–induced apoptosis in melanoma cells
Susan K. Gillespie; Xu Dong Zhang; Peter Hersey
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Camptothecin- and etoposide-induced apoptosis in human leukemia cells is independent of cell death receptor-3 and -4 aggregation but accelerates tumor necrosis factor–related apoptosis-inducing ligand–mediated cell death
Stephane Bergeron; Myriam Beauchemin; Richard Bertrand
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Growth inhibitory effects of celecoxib in human umbilical vein endothelial cells are mediated through G1 arrest via multiple signaling mechanisms
Ho-Pi Lin; Samuel K. Kulp; Ping-Hui Tseng; Ya-Ting Yang; Chi-Cheng Yang; Chang-Shi Chen; Ching-Shih Chen
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Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor–induced hepatotoxicity is mediated by Kupffer cells
Marlena M. Westcott; Ralph J. Abi-Habib; Kimberley A. Cohen; Mark C. Willingham; Shihui Liu; Thomas H. Bugge; Stephen H. Leppla; Arthur E. Frankel
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Enhanced efficacy of therapy with antisense BCL-2 oligonucleotides plus anti-CD20 monoclonal antibody in scid mouse/human lymphoma xenografts
Mitchell R. Smith; Fang Jin; Indira Joshi
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Commentary

Confirmation and prevention of targeted toxicity by a recombinant fusion toxin
Robert J. Kreitman
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Correction

Article on anti-STAT3 and prostate cancer
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